Results 151 to 160 of about 2,290,618 (347)

Binding Selectivity Analysis from Alchemical Receptor Hopping and Swapping Free Energy Calculations [PDF]

arXiv
We present receptor hopping and receptor swapping free energy estimation protocols based on the Alchemical Transfer Method (ATM) to model the binding selectivity of a set of ligands to two arbitrary receptors. The receptor hopping protocol, where a ligand is alchemically transferred from one receptor to another in one simulation, directly yields the ...
arxiv  

Age-related decrease of GABAA receptor subunits and glutamic acid decarboxylase in the rat inferior colliculus [PDF]

, 1994
Antonia Gutiérrez, Zafar U. Khan, SJ Morris, AL de Blas   +3 more
openalex   +1 more source

Investigations in GABAA receptor antibody-associated encephalitis

Neurology, 2017
M. Spatola, Mar Petit-Pedrol, M. Simabukuro, T. Armangué, Fernanda J. Castro, M. I. Barceló Artigues, M. R. Julià Benique, L. Benson, M. Gorman, A. Felipe, Ruben L. Caparó Oblitas, M. Rosenfeld, F. Graus, J. Dalmau   +13 more
semanticscholar   +1 more source

Post‐exercise neural plasticity is augmented by adding blood flow restriction during low work rate arm cycling

Experimental Physiology, EarlyView.
Abstract Blood flow restriction (BFR) combined with low work rate exercise can enhance muscular and cardiovascular fitness. However, whether neural mechanisms mediate these enhancements remains unknown. This study examined changes in corticospinal excitability and motor cortical inhibition following arm cycle ergometry with and without BFR.
Mikaela L. Frechette, Summer B. Cook, Brendan R. Scott, Jane Tan, Ann‐Maree Vallence   +4 more
wiley   +1 more source

Amelioration of hepatic encephalopathy by pharmacologic antagonism of the GABAA-benzodiazepine receptor complex in a rabbit model of fulminant hepatic failure

, 1987
Mark L. Bassett, Kevin D. Mullen, Phil Skolnick, E. Anthony Jones   +3 more
openalex   +1 more source

Intraburst kinetic properties of the GABAA receptor main conductance state of mouse spinal cord neurones in culture. [PDF]

, 1990
Roy E. Twyman, Connie J. Rogers, Robert L. Macdonald   +2 more
openalex   +1 more source

Membrane progesterone and oestrogen receptors modulate GABAergic transmission in the prefrontal cortex of prepubertal male, but not female, mice

Experimental Physiology, EarlyView.
Abstract The sex hormones progesterone (P) and oestrogen (E) reorganize GABAergic transmission in the prefrontal cortex (PFC) during the transition from childhood to adolescence, generating a new excitatory–inhibitory balance necessary for the computational capacity of the mature PFC.
Aitana Vázquez‐Sola, Hortensia Torres‐Torrelo, Josué García Yagüe   +2 more
wiley   +1 more source

Kinetics of open channel block by penicillin of single GABAA receptor channels from mouse spinal cord neurones in culture. [PDF]

, 1992
Roy E. Twyman, R M Green, Robert L. Macdonald   +2 more
openalex   +1 more source

Translating physiology of the arterial chemoreflex into novel therapeutic interventions targeting carotid bodies in cardiometabolic disorders

The Journal of Physiology, EarlyView.
Abstract figure legend The carotid body develops aberrant high activity in chronic heart failure, resistant hypertension, obstructive sleep apnoea (OSA) and diabetes. Hyperactivity of the carotid body leads to both high tonicity and increased sensitivity of the arterial chemoreflex with resultant sympathoexcitation.
Tymoteusz Żera, Bartłomiej Paleczny, Maciej Siński, Sílvia V. Conde, Krzysztof Narkiewicz, Piotr Ponikowski, Julian F.R. Paton, Piotr Niewiński   +7 more
wiley   +1 more source

Immunocytochemical detection of astrocyte GABAA receptors in cat visual cortex. [PDF]

, 1993
A. M. Rosier, Lut Arckens, Guy A. Orban, Frans Vandesande   +3 more
openalex   +1 more source