Results 161 to 170 of about 2,290,618 (347)

GABAA receptor: Positive and negative allosteric modulators

Neuropharmacology, 2018
R. Olsen
semanticscholar   +1 more source

Changes in the cortical GABAergic inhibitory system with ageing and ageing‐related neurodegenerative diseases

The Journal of Physiology, EarlyView.
Abstract figure legend With ageing and age‐related neurodegenerative diseases, the amount of GABA and GABAergic inhibition as well as the modulation (indicated by sine wave) of GABAergic inhibition is reduced, whereas excitation is increased. In many parts of the brain, this leads to a mismatch of facilitatory (green neurons) and inhibitory (red ...
Wolfgang Taube, Benedikt Lauber
wiley   +1 more source

MRI Characteristics of Autoimmune Encephalitis With Autoantibodies to GABAA Receptor: A Case Series. [PDF]

Neurol Neuroimmunol Neuroinflamm, 2022
Deng B, Cai M, Qiu Y, Liu X, Yu H, Zhang X, Huang H, Zhao X, Yang W, Dong S, Jin L, Chu S, Chen X.   +12 more
europepmc   +2 more sources

Properties of a Novel GABAA Receptor γ2 Subunit Mutation Associated With Seizures

Journal of Pharmacological Sciences, 2013
We recently identified a novel missense mutation of the γ2 subunit at position 40 with serine (N40S) of the GABAA receptor from a patient with epilepsy. Here, we report properties of the mutant receptor using the whole cell patch clamp technique.
Keisuke Migita, Junko Yamada, Yoshikazu Nikaido, XiuYu Shi, Sunao Kaneko, Shinichi Hirose, Shinya Ueno   +6 more
doaj  

Possible involvement of GABAA receptor in relaxation of rat stomach longitudinal muscle by activating nonadrenergic-noncholinergic neuron

, 1987
Fumiyoshi Kobayashi, Shingo Yano, Kazuo Watanabe   +2 more
openalex   +1 more source

Synaptic communication within the microcircuits of pyramidal neurons and basket cells in the mouse prefrontal cortex

The Journal of Physiology, EarlyView.
Abstract figure legend Basket cells represent critical building blocks of neuronal circuits in cortical regions by providing GABAergic innervation to the perisomatic region of their postsynaptic partners. In the mouse prelimbic cortex, the two basket cell types expressing parvalbumin or cholecystokinin/type I cannabinoid receptor receive unitary ...
Zsuzsanna Fekete, Filippo Weisz, Mária Rita Karlócai, Judit M. Veres, Tibor Andrási, Norbert Hájos   +5 more
wiley   +1 more source

Cloning of GABAA/benzodiazepine receptor subunit cDNAs

, 1987
N Fujita, David Burt, MG Darlison, T. Gleneorse, Anne Stephenson, E.A. Barnard, Peter W. Schofield, P. H. Seeburg, Henrique Rodrigues, J. Ramachandran   +9 more
openalex   +1 more source

Membrane trafficking of synaptic adhesion molecules

The Journal of Physiology, EarlyView.
Abstract figure legend Synaptic cellular adhesion molecules are surface transmembrane receptors that have been shown to internalize via endocytosis, and possibly also recycle, in a process that has been linked to the function and the turnover of the synaptic contact site.
Cristian A. Bogaciu, Silvio O. Rizzoli
wiley   +1 more source

α5-GABAA Receptor Modulation Reverses Behavioral and Neurophysiological Correlates of Psychosis in Rats with Ventral Hippocampal Alzheimer's Disease-like Pathology. [PDF]

Int J Mol Sci, 2023
Eassa NE, Perez SM, Boley AM, Elam HB, Sharmin D, Cook JM, Lodge DJ.   +6 more
europepmc   +1 more source

Neurochemical studies on γ-aminobutyric acid(GABA) receptor.(XV) Pharmacological properties of purified GABAA/benzodiazepine receptor complex from bovine cerebral cortex and its co-purification with [35S]t-butylbicyclophosphorothionate binding site by benzodiazepine affinity column chromatography

, 1986
Junichi Taguchi, Kinya Kuriyama
openalex   +1 more source