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Synthesis and evaluation of photoaffinity labeling reagents for identifying binding sites of sulfated neurosteroids on NMDA and GABAA receptors. [PDF]
RSC AdvQian M +8 more
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Lactobacillus brevis M2-Fermented Whey Protein Hydrolysate Increases Slow-Wave Sleep via GABAA Receptors in Rodent Models. [PDF]
FoodsLee H +6 more
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Thalamic extrasynaptic GABAA receptors are required for typical absence seizures
, 2009 Giuseppe Di Giovanni +5 more
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Pharmacological modulation of GABAA receptors
Current Opinion in Pharmacology, 2021Ligand-gated ion channels are integral membrane proteins that activate through a change in conformation upon transmitter binding and were identified as key players of brain function. GABAA receptors are major inhibitory ligand-gated ion channels of this protein family.
Frédéric, Knoflach, Daniel, Bertrand
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Pharmacology & Therapeutics, 1995
gamma-Aminobutyric acid (GABA)A receptors for the inhibitory neurotransmitter GABA are likely to be found on most, if not all, neurons in the brain and spinal cord. They appear to be the most complicated of the superfamily of ligand-gated ion channels in terms of the large number of receptor subtypes and also the variety of ligands that interact with ...
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gamma-Aminobutyric acid (GABA)A receptors for the inhibitory neurotransmitter GABA are likely to be found on most, if not all, neurons in the brain and spinal cord. They appear to be the most complicated of the superfamily of ligand-gated ion channels in terms of the large number of receptor subtypes and also the variety of ligands that interact with ...
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Brain Research Reviews, 1999
Recent advances in molecular biology and complementary information derived from neuropharmacology, biochemistry and behavior have dramatically increased our understanding of various aspects of GABAA receptors. These studies have revealed that the GABAA receptor is derived from various subunits such as alpha1-alpha6, beta1-beta3, gamma1-gamma3, delta ...
A K, Mehta, M K, Ticku
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Recent advances in molecular biology and complementary information derived from neuropharmacology, biochemistry and behavior have dramatically increased our understanding of various aspects of GABAA receptors. These studies have revealed that the GABAA receptor is derived from various subunits such as alpha1-alpha6, beta1-beta3, gamma1-gamma3, delta ...
A K, Mehta, M K, Ticku
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Neurosteroid modulation of GABAA receptors
Progress in Neurobiology, 2003Certain metabolites of progesterone and deoxycorticosterone are established as potent and selective positive allosteric modulators of the gamma-aminobutyric acid type A (GABA(A)) receptor. Upon administration these steroids exhibit clear behavioural effects that include anxiolysis, sedation and analgesia, they are anticonvulsant and at high doses ...
Lambert, Jeremy J. +4 more
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Trends in Neurosciences, 1996
In a recent issue, a review addressed the important question of which GABAA-receptor subtypes occur in our brain1xMcKernan, R.M. and Whiting, P.J. Trends Neurosci. 1996; 19: 139–143Abstract | Full Text PDF | PubMed | Scopus (939)See all References1.
Erwin Sigel, Kai Kannenberg
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In a recent issue, a review addressed the important question of which GABAA-receptor subtypes occur in our brain1xMcKernan, R.M. and Whiting, P.J. Trends Neurosci. 1996; 19: 139–143Abstract | Full Text PDF | PubMed | Scopus (939)See all References1.
Erwin Sigel, Kai Kannenberg
openaire +1 more source