Results 91 to 100 of about 914,049 (192)

A GABAergic projection from the zona incerta to cortex promotes cortical neuron development

Science, 2015
Circuits for brain building The brain is made up of circuits. Chen and Kriegstein analyzed how one particular circuit functions differently in developing and mature mouse brains (see the Perspective by Spitzer).
Jiadong Chen, A. Kriegstein
semanticscholar   +1 more source

Defined co-cultures of glutamatergic and GABAergic neurons with a mutation in DISC1 reveal aberrant phenotypes in GABAergic neurons

BMC Neuroscience
Abstract Background Mutations in the gene DISC1 are associated with increased risk for schizophrenia, bipolar disorder and major depression. The study of mutated DISC1 represents a well-known and comprehensively characterized approach to understand neuropsychiatric disease mechanisms.
Heider, Johanna, Stahl, Aaron, Sperlich, Denise, Hartmann, Sophia-Marie, Vogel, Sabrina, Breitmeyer, Ricarda, Templin, Markus F., Volkmer, Hansjürgen   +7 more
openaire   +4 more sources

Excitatory neuron-prone prion propagation and excitatory neuronal loss in prion-infected mice

Frontiers in Molecular Neuroscience
The accumulation of a disease-specific isoform of prion protein (PrPSc) and histopathological lesions, such as neuronal loss, are unevenly distributed in the brains of humans and animals affected with prion diseases. This distribution varies depending on
Temuulen Erdenebat, Yusuke Komatsu, Nozomi Uwamori, Misaki Tanaka, Takashi Hoshika, Takeshi Yamasaki, Ayano Shimakura, Akio Suzuki, Akio Suzuki, Toyotaka Sato, Toyotaka Sato, Motohiro Horiuchi, Motohiro Horiuchi, Motohiro Horiuchi   +13 more
doaj   +1 more source

Striatal function scrutinized through the PAN-TAN-FSI triumvirate

Frontiers in Cellular Neuroscience
Understanding the information encoded by distinct components of the neuronal circuitry in the striatum represents an avenue for elucidating the role of this subcortical region in adaptive behavior and its dysfunction in pathological conditions.
Paul Apicella, Anne-Caroline Martel, Kevin Marche   +2 more
doaj   +1 more source

Transcriptomic insights into fate choice of pallial versus subpallial GABAergic neurons

Nature Communications
The activity of the telencephalon is shaped by pallial and subpallial GABAergic neurons, two large populations produced in the embryonic ganglionic eminence.
Lijuan Sun, Feng Xiong, Feier Huang, Shuangshuang Dong, Pei Zhu, Pengfei Jiang, Baoshen Zhang, Xinxin Zhang, Jie Sun, Hanchuan Peng, Chunjie Zhao   +10 more
doaj   +1 more source

Thyroid hormone action during GABAergic neuron maturation: The quest for mechanisms. [PDF]

Front Endocrinol (Lausanne), 2023
Richard S, Ren J, Flamant F.
europepmc   +1 more source

Activation of DMH GABAergic neurons, but not local GABAergic AgRP neurons, attenuates chronic stress-induced POMC neuron hyperactivity

ABSTRACT Identifying the neural circuits engaged and reshaped by chronic stress is critical for understanding how adaptive responses shift to maladaptive behaviors that contribute to stress-related disorders. Our previous work demonstrates that chronic unpredictable stress (CUS) induces a persistent increase in the ...
Chen, Yuting, Moghaddam, Amin Karimi, Du, Quansheng, Lei, Yun, Lu, Xin-Yun   +4 more
openaire   +2 more sources

GABAergic synapses from the ventral lateral septum to the paraventricular nucleus of hypothalamus modulate anxiety

Frontiers in Neuroscience
Emotional disorders, such as anxiety and depression, represent a major societal problem; however, the underlying neurological mechanism remains unknown. The ventral lateral septum (LSv) is implicated in regulating processes related to mood and motivation.
Ying-Juan Liu, Yan Wang, Jiao-Wen Wu, Jie Zhou, Bai-Lin Song, Yi Jiang, Lai-Fu Li   +6 more
doaj   +1 more source

Corrigendum to: Propofol differentially induces unconsciousness and respiratory depression through distinct interactions between GABAA receptor and GABAergic neuron in corresponding nuclei. [PDF]

Acta Biochim Biophys Sin (Shanghai), 2023
Jiang J, Jiao Y, Gao P, Yin W, Zhou W, Zhang Y, Liu Y, Wen D, Wang Y, Zhou L, Yu T, Yu W.   +11 more
europepmc   +1 more source

Ventral Pallidal GABAergic Neuron Calcium Activity Encodes Cue-Driven Reward Seeking and Persists in the Absence of Reward Delivery. [PDF]

J Neurosci, 2023
Scott A, Palmer D, Newell B, Lin I, Cayton CA, Paulson A, Remde P, Richard JM.   +7 more
europepmc   +1 more source