Temporal Drivers of Opioid-Related ED Visits: An Ensemble Machine Learning Study With Consensus-Based Feature Attribution. [PDF]
Dixon RJ, Price ET.
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The evolving treatment landscape of restless legs syndrome. [PDF]
Mogavero MP +4 more
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Treatment of neuropathic pain in diabetic rats with synergistic combinations of nortriptyline + tramadol and nortriptyline + ibuprofen. [PDF]
Pérez-Hernández MG +7 more
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Gabapentin to achieve HIV viral load suppression in people with risky drinking in Mbarara, Uganda: study protocol for a randomized, double-blinded, placebo-controlled trial (GRAIL). [PDF]
Truong V +11 more
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Gabapentsal ameliorate cisplatin-induced vomiting in pigeons: neurochemical evidences and the involvement of serotonin and dopamine modulation. [PDF]
Ahmad M +8 more
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Losmapimod, an Oral Anti-p38 MAP Kinase, Demonstrates Anti-Neuropathic and Anti-Inflammatory Effects in Rat Acute Pain. [PDF]
Soued M +4 more
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Summary: The amino acid antiepileptic drug (AED) gabapentin (GBP) is indicated for adjunctive use in the treatment of partial seizures with or without becoming secondarily generalized in individuals older than 12 years. GBP was about as potent as phenytoin in the maximal electroshock test, but had a different profile of efficacy than standard ...
A, Beydoun +2 more
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Gabapentin is a structural analogue of the neurotransmitter gamma-aminobutyric acid (GABA) approved for use in adults with postherpetic neuralgia. Gabapentin does not bind to GABA(A) or GABA(B) receptors. Its mechanism of action in humans is unclear, but may involve binding to alpha2delta calcium channel subunits in animal models.
Monique P, Curran, Antona J, Wagstaff
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Gabapentin [or 1-(aminomethyl)cyclohexaneacetic acid], C(9)H(17)NO(2), exists as a zwitterion [1-(ammoniomethyl)cyclohexaneacetate] in the solid state. The crystal structures and bonding networks of two new monoclinic polymorphs (beta-gabapentin and gamma-gabapentin) are studied and compared with a previously reported gabapentin polymorph [alpha ...
Hayley A, Reece, Demetrius C, Levendis
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