Results 111 to 120 of about 346,213 (330)

Reviewing HIV-1 Gag Mutations in Protease Inhibitors Resistance: Insights for Possible Novel Gag Inhibitor Designs

open access: yesMolecules, 2019
HIV protease inhibitors against the viral protease are often hampered by drug resistance mutations in protease and in the viral substrate Gag. To overcome this drug resistance and inhibit viral maturation, targeting Gag alongside protease rather than ...
Chinh Tran-To Su   +2 more
doaj   +1 more source

Live-cell observation of cytosolic HIV-1 assembly onset reveals RNA-interacting Gag oligomers [PDF]

open access: bronze, 2015
Jelle Hendrix   +8 more
openalex   +1 more source

4D Printing of Magnetically Responsive Shape Memory Polymers: Toward Sustainable Solutions in Soft Robotics, Wearables, and Biomedical Devices

open access: yesAdvanced Science, EarlyView.
Merging 4D printing with magneto‐responsive shape memory polymers opens new avenues for intelligent, reconfigurable systems. This review navigates cutting‐edge fabrication techniques, magnetic fillers, and smart polymer matrices, unveiling their potential in soft robotics, biomedical devices, and wearable tech.
Kiandokht Mirasadi   +7 more
wiley   +1 more source

Susceptibility of Human Immunodeficiency Virus Type 1 to the Maturation Inhibitor Bevirimat Is Modulated by Baseline Polymorphisms in Gag Spacer Peptide 1 [PDF]

open access: bronze, 2009
Kurt Van Baelen   +9 more
openalex   +1 more source

Increased Blood Flow and Tendon Swelling Precedes Vascular Expansion and Tissue Matrix Changes In Early Human Tendinopathy: A Potential Window for Superior Treatment Response

open access: yesAdvanced Science, EarlyView.
Human participants with early‐ or chronic‐stage tendinopathy and healthy controls are investigated using ultrasound Doppler, 3T and 7T MRI, and tendon biopsies. Tendon swelling and hyperperfusion are evident early, while vascular growth and extracellular matrix changes are most pronounced in chronic tendinopathy. Early intervention may provide superior
Max F. R. Merkel   +11 more
wiley   +1 more source

Le Gag

open access: yesLmM, 2015
La notion de gag n'appartient pas en propre à la bande dessinée. Il y a des gags au cinéma, ils caractérisent même un genre de cinéma, le cinéma burlesque. Il y a des gags à la télévision, pensez aux « vidéo-gags ». Il y a, depuis beaucoup plus longtemps, des gags au théâtre et dans tous les arts vivants qui mettent en scène le corps d'un acteur, le ...
openaire   +4 more sources

In-vivo mutation rates and fitness landscape of HIV-1

open access: yes, 2016
Mutation rates and fitness costs of deleterious mutations are difficult to measure in vivo but essential for a quantitative understanding of evolution. Using whole genome deep sequencing data from longitudinal samples during untreated HIV-1 infection, we
Albert, Jan   +4 more
core   +1 more source

5′tRF‐GlyGCC Promotes Breast Cancer Progression via LDHA‐Mediated Glycolysis and Macrophage Polarization

open access: yesAdvanced Science, EarlyView.
5’tRF‐GlyGCC promotes breast cancer malignancy by binding to LDHA. This interaction, facilitated by FGFR1 and LDHA phosphorylation, enhances glycolysis. Additionally, 5’tRF‐GlyGCC/LDHA signaling recruits and polarizes macrophages into a pro‐tumor M2 state via CCL7, thus remodeling the tumor microenvironment.
Cheng Yi   +17 more
wiley   +1 more source

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