Results 71 to 80 of about 904,948 (308)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

What can eye movements tell about students’ interpretations of contextual graphs? A methodological study on the use of the eye-mind hypothesis in the domain of functions

Frontiers in Education, 2022
IntroductionThe use of eye tracking (ET) in mathematics education research has increased in recent years. Eye tracking is a promising research tool in the domain of functions, especially in graph interpretation. It promises to gain insights into learners’
Aylin Thomaneck, Maike Vollstedt, Maike Schindler   +2 more
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

DHPV: a distributed algorithm for large-scale graph partitioning

Journal of Big Data, 2020
Big graphs are part of the movement of “Not Only SQL” databases (also called NoSQL) focusing on the relationships between data, rather than the values themselves.
Wilfried Yves Hamilton Adoni, Tarik Nahhal, Moez Krichen, Abdeltif El byed, Ismail Assayad   +4 more
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Occupancy probabilities in superintegrable bosonic networks

Nuclear Physics B
We associate a bosonic network to each complete bipartite graph. A Hamiltonian is defined with hopping terms on the edges of the graph, and a global interaction term depending on the vertex sets.
Lachlan Bennett, Angela Foerster, Phillip S. Isaac, Jon Links   +3 more
doaj   +1 more source

Graph-Based Divide and Conquer Method for Parallelizing Spatial Operations on Vector Data

Remote Sensing, 2014
In computer science, dependence analysis determines whether or not it is safe to parallelize statements in programs. In dealing with the data-intensive and computationally intensive spatial operations in processing massive volumes of geometric features ...
Xiaochen Kang, Xiangguo Lin
doaj   +1 more source

Distance matrices for conjugate skew gain graphs

Discrete Mathematics, Algorithms and Applications
A conjugate skew gain graph is a skew gain graph with the labels (also called, the conjugate skew gains) from the field of complex numbers on the oriented edges such that they get conjugated when we reverse the orientation. In this paper, we introduce distance matrices for conjugate skew gain graphs and characterize balanced conjugate skew gain graphs
K. Shahul Hameed, K. O. Ramakrishnan, K. Biju   +2 more
openaire   +3 more sources

On the Characteristic Polynomial of Skew Gain Graphs

, 2020
Gain graphs are graphs where the edges are given some orientation and labeled with the elements (called gains) from a group so that gains are inverted when we reverse the direction of the edges. Generalizing the notion of gain graphs, skew gain graphs have the property that the gain of a reversed edge is the image of edge gain under an anti-involution.
Hameed, K. S., Roy, Roshni T., Soorya, P., Germina, K. A.   +3 more
openaire   +3 more sources

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source