Results 41 to 50 of about 158,365 (141)
MicrobiologyOpen, 2019 Bacteria can utilize diverse sugars as carbon and energy source, but the regulatory mechanisms directing the choice of the preferred substrate are often poorly understood.
Tamara Aleksandrzak‐Piekarczyk +2 more
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Biomolecules, 2015 Studying the regulation of transcription of the gal operon that encodes the amphibolic pathway of d-galactose metabolism in Escherichia coli discerned a plethora of principles that operate in prokaryotic gene regulatory processes.
Dale E.A. Lewis, Sankar Adhya
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Translation Initiation Control of RNase E-Mediated Decay of Polycistronic gal mRNA
Frontiers in Molecular Biosciences, 2020 In bacteria, mRNA decay is a major mechanism for regulating gene expression. In Escherichia coli, mRNA decay initiates with endonucleolytic cleavage by RNase E. Translating ribosomes impede RNase E cleavage, thus providing stability to mRNA.
Heung Jin Jeon +6 more
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The functional mutational landscape of the lacZ gene
iScience, 2023 Summary: The lacZ gene of Escherichia coli encodes β-galactosidase (β-gal), a lactose metabolism enzyme of the lactose operon. Previous chemical modification or site-directed mutagenesis experiments have identified 21 amino acids that are essential for β-
Marc A. Beal +5 more
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A modified consumer inkjet for spatiotemporal control of gene expression.
PLoS ONE, 2009 This paper presents a low-cost inkjet dosing system capable of continuous, two-dimensional spatiotemporal regulation of gene expression via delivery of diffusible regulators to a custom-mounted gel culture of E. coli. A consumer-grade, inkjet printer was
Daniel J Cohen +2 more
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Development of a
Microbial Cell Factories, 2010 Background B. subtilis is an important organism in the biotechnological application. The efficient expression system is desirable in production of recombinant gene products in B. subtilis.
Ming Yang M +3 more
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The incoherent feed‐forward loop can generate non‐monotonic input functions for genes
Molecular Systems Biology, 2008 Gene regulation networks contain recurring circuit patterns called network motifs. One of the most common network motif is the incoherent type 1 feed‐forward loop (I1‐FFL), in which an activator controls both gene and repressor of that gene.
Shai Kaplan +3 more
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VIEW, EarlyView.We summarize the taxonomic characteristics, capabilities to adhere to and invade host cells, extra‐oral ectopic colonization pathways, and major pathogenic mechanisms of Fusobacterium nucleatum, and explore the regulation of F. nucleatum’s pathogenesis, aiming to provide references and assistance for the development of clinical interventions and future
Zhiwei Guan, Houbao Qi, Qiang Feng
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Molecular Microbiology, EarlyView.A novel TetR‐like regulator (EppR) has been identified to repress genes encoding DNA polymerase V in Acinetobacter baumannii through the direct binding of a conserved EppR motif in their promoters. EppR works with previously identified regulator UmuDAb to serve as co‐regulators of these genes. In response to DNA damage and/or environmental stress, both
Brian Nguyen +6 more
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Molecular Microbiology, EarlyView.COL is an unusual “model” strain of Staphylococcus aureus that exhibits slow growth and multidrug antibiotic tolerance. This phenotype is primarily due to a mutation in Prs, which synthesizes the core metabolite phosphoribosyl pyrophosphate (PRPP). Introduction of the COL Prs allele into the antibiotic‐susceptible strain Newman confers tolerance, while
Claire E. Stevens +5 more
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