Galactose Metabolism Plays a Crucial Role in Biofilm Formation by Bacillus subtilis [PDF]
Galactose is a common monosaccharide that can be utilized by all living organisms via the activities of three main enzymes that make up the Leloir pathway: GalK, GalT, and GalE.
Beauregard, Pascale+4 more
core +1 more source
An ABC transporter containing a forkhead-associated domain interacts with a serine-threonine protein kinase and is required for growth of Mycobacterium tuberculosis in mice [PDF]
Forkhead-associated (FHA) domains are modular phosphopeptide recognition motifs with a striking preference for phosphothreonine-containing epitopes. FHA domains have been best characterized in eukaryotic signaling pathways but have been identified in six
Buxton, RS+8 more
core +2 more sources
The incoherent feed‐forward loop can generate non‐monotonic input functions for genes
Gene regulation networks contain recurring circuit patterns called network motifs. One of the most common network motif is the incoherent type 1 feed‐forward loop (I1‐FFL), in which an activator controls both gene and repressor of that gene.
Shai Kaplan+3 more
doaj +1 more source
Unraveling the molecular basis of subunit specificity in P pilus assembly by mass spectrometry [PDF]
P pili are multisubunit fibers essential for the attachment of uropathogenic Escherichia coli to the kidney. These fibers are formed by the noncovalent assembly of six different homologous subunit types in an array that is strictly defined in terms of ...
A. E. Ashcroft+28 more
core +2 more sources
ABSTRACT Rhizorhabdus wittichii RW1 is known for its ability to degrade polycyclic aromatic hydrocarbons, such as dibenzo‐p‐dioxin (DD) and dibenzofuran (DF). We hypothesized that the R. wittichii RW1 benzoate 1,2‐dioxygenase shares electron transfer components with the DD/DF angular dioxygenase (DxnA1A2), similar to many aromatic hydrocarbon degrading
Igor Ivanovski+2 more
wiley +1 more source
Transcriptional control of the H-NS antagonists LeuO and RcsB-BglJ in Escherichia coli [PDF]
The bacterial nucleoid-associated protein (NAP) H-NS is involved in the organization and compaction of the bacterial chromatin and acts as a global respressor, mainly of genes that have been acquired by horizontal gene transfer and that are related to ...
Stratmann, Thomas
core
Revision and expansion of the genus Spirirestis (Tolypothrichaceae, Cyanobacteria)
Abstract Recent phylogenetic analyses of members of the Tolypothrichaceae (Nostocales, Cyanobacteria) based on 16S rRNA gene sequence data have demonstrated that the soil‐inhabiting members of the family belong to a clade separate from the aquatic and subaerial members of the family.
Jeffrey R. Johansen+14 more
wiley +1 more source
Biological Consequences of Tightly Bent DNA: The Other Life of a Macromolecular Celebrity [PDF]
The mechanical properties of DNA play a critical role in many biological functions. For example, DNA packing in viruses involves confining the viral genome in a volume (the viral capsid) with dimensions that are comparable to the DNA persistence length ...
Garcia, Hernan G.+8 more
core +3 more sources
COL is an unusual “model” strain of Staphylococcus aureus that exhibits slow growth and multidrug antibiotic tolerance. This phenotype is primarily due to a mutation in Prs, which synthesizes the core metabolite phosphoribosyl pyrophosphate (PRPP). Introduction of the COL Prs allele into the antibiotic‐susceptible strain Newman confers tolerance, while
Claire E. Stevens+5 more
wiley +1 more source
DASH: a versatile and high‐capacity gene stacking system for plant synthetic biology
Summary DNA assembly systems based on the Golden Gate method are popular in synthetic biology but have several limitations: small insert size, incompatibility with other cloning platforms, DNA domestication requirement, generation of fusion scars, and lack of post‐assembly modification.
Chengsong Zhao+2 more
wiley +1 more source