Results 51 to 60 of about 26,227 (179)

An ABC transporter containing a forkhead-associated domain interacts with a serine-threonine protein kinase and is required for growth of Mycobacterium tuberculosis in mice [PDF]

, 2005
Forkhead-associated (FHA) domains are modular phosphopeptide recognition motifs with a striking preference for phosphothreonine-containing epitopes. FHA domains have been best characterized in eukaryotic signaling pathways but have been identified in six
Buxton, RS, Colston, MJ, Curry, JM, Gohil, K, Hunt, DM, Rickman, L, Smerdon, SJ, Strom, M, Whalan, R   +8 more
core   +2 more sources

Galactose Metabolism Plays a Crucial Role in Biofilm Formation by Bacillus subtilis [PDF]

, 2014
Galactose is a common monosaccharide that can be utilized by all living organisms via the activities of three main enzymes that make up the Leloir pathway: GalK, GalT, and GalE.
Beauregard, Pascale, Chai, Yunrong, Kolter, Roberto Guillermo, Losick, Richard M., Vlamakis, Hera C   +4 more
core   +1 more source

The incoherent feed‐forward loop can generate non‐monotonic input functions for genes

Molecular Systems Biology, 2008
Gene regulation networks contain recurring circuit patterns called network motifs. One of the most common network motif is the incoherent type 1 feed‐forward loop (I1‐FFL), in which an activator controls both gene and repressor of that gene.
Shai Kaplan, Anat Bren, Erez Dekel, Uri Alon   +3 more
doaj   +1 more source

Analysis of Benzoate 1,2‐Dioxygenase Identifies Shared Electron Transfer Components With DxnA1A2 in Rhizorhabdus wittichii RW1

Journal of Basic Microbiology, EarlyView.
ABSTRACT Rhizorhabdus wittichii RW1 is known for its ability to degrade polycyclic aromatic hydrocarbons, such as dibenzo‐p‐dioxin (DD) and dibenzofuran (DF). We hypothesized that the R. wittichii RW1 benzoate 1,2‐dioxygenase shares electron transfer components with the DD/DF angular dioxygenase (DxnA1A2), similar to many aromatic hydrocarbon degrading
Igor Ivanovski, Suha Eleya, Gerben J. Zylstra   +2 more
wiley   +1 more source

Identification of EppR, a Second Repressor of Error‐Prone DNA Polymerase Genes in Acinetobacter baumannii

Molecular Microbiology, EarlyView.
A novel TetR‐like regulator (EppR) has been identified to repress genes encoding DNA polymerase V in Acinetobacter baumannii through the direct binding of a conserved EppR motif in their promoters. EppR works with previously identified regulator UmuDAb to serve as co‐regulators of these genes. In response to DNA damage and/or environmental stress, both
Brian Nguyen, Carly Ching, Ashley MacGuire, Pranav Casula, Connor Newman, Faith Finley, Veronica G. Godoy   +6 more
wiley   +1 more source

Transcriptional control of the H-NS antagonists LeuO and RcsB-BglJ in Escherichia coli [PDF]

, 2012
The bacterial nucleoid-associated protein (NAP) H-NS is involved in the organization and compaction of the bacterial chromatin and acts as a global respressor, mainly of genes that have been acquired by horizontal gene transfer and that are related to ...
Stratmann, Thomas
core  

Unraveling the molecular basis of subunit specificity in P pilus assembly by mass spectrometry [PDF]

, 2008
P pili are multisubunit fibers essential for the attachment of uropathogenic Escherichia coli to the kidney. These fibers are formed by the noncovalent assembly of six different homologous subunit types in an array that is strictly defined in terms of ...
A. E. Ashcroft, Benesch, Choudhury, D. Verger, Dodson, E. Paci, G. Waksman, Gong, H. Remaut, Jacob-Dubuisson, Jacob-Dubuisson, Jones, R. J. Rose, Remaut, Remaut, Roberts, Rose, S. E. Radford, Sauer, Sauer, Sauer, Saulino, Soto, Stathopoulos, T. Daviter, Thanassi, Thanassi, Verger, Zavialov   +28 more
core   +2 more sources

Staphylococcus aureus COL: An Atypical Model Strain of MRSA That Exhibits Slow Growth and Antibiotic Tolerance due to a Mutation in PRPP Synthetase

Molecular Microbiology, EarlyView.
COL is an unusual “model” strain of Staphylococcus aureus that exhibits slow growth and multidrug antibiotic tolerance. This phenotype is primarily due to a mutation in Prs, which synthesizes the core metabolite phosphoribosyl pyrophosphate (PRPP). Introduction of the COL Prs allele into the antibiotic‐susceptible strain Newman confers tolerance, while
Claire E. Stevens, Ashley T. Deventer, Paul R. Johnston, Phillip T. Lowe, Alisdair B. Boraston, Joanne K. Hobbs   +5 more
wiley   +1 more source

DASH: a versatile and high‐capacity gene stacking system for plant synthetic biology

Plant Biotechnology Journal, EarlyView.
Summary DNA assembly systems based on the Golden Gate method are popular in synthetic biology but have several limitations: small insert size, incompatibility with other cloning platforms, DNA domestication requirement, generation of fusion scars, and lack of post‐assembly modification.
Chengsong Zhao, Anna N. Stepanova, Jose M. Alonso   +2 more
wiley   +1 more source

Molecular Distributions in Gene Regulatory Dynamics [PDF]

, 2010
We show how one may analytically compute the stationary density of the distribution of molecular constituents in populations of cells in the presence of noise arising from either bursting transcription or translation, or noise in degradation rates ...
Acar, Arnold, Berg, Blake, Blake, Bobrowski, Cai, Chubb, Elowitz, Feistel, Fraser, Friedman, Gardiner, Gardner, Gillespie, Golding, Goodwin, Griffith, Griffith, Hawkins, Hierro, Horsthemke, Jacob, Kaern, Kepler, Lasota, Lipniacki, Lipshtat, Mackey, Mariani, Marta Tyran-Kamińska, Michael C. Mackey, Ochab-Marcinek, Ochab-Marcinek, Oppenheim, Othmer, Pichór, Polynikis, Raj, Raj, Raser, Romain Yvinec, Scott, Selgrade, Shahrezaei, Shahrezaei, Shahrezaei, Sigal, Smith, Song, Swain, Titular, Wilemski, Yildirim, Yu, Zacharioudakis   +55 more
core   +5 more sources