Results 81 to 90 of about 27,037 (204)

Staphylococcus aureus COL: An Atypical Model Strain of MRSA That Exhibits Slow Growth and Antibiotic Tolerance due to a Mutation in PRPP Synthetase

open access: yesMolecular Microbiology, Volume 124, Issue 3, Page 189-203, September 2025.
COL is an unusual “model” strain of Staphylococcus aureus that exhibits slow growth and multidrug antibiotic tolerance. This phenotype is primarily due to a mutation in Prs, which synthesizes the core metabolite phosphoribosyl pyrophosphate (PRPP). Introduction of the COL Prs allele into the antibiotic‐susceptible strain Newman confers tolerance, while
Claire E. Stevens   +5 more
wiley   +1 more source

The dual transcriptional regulator CysR in Corynebacterium glutamicum ATCC 13032 controls a subset of genes of the McbR regulon in response to the availability of sulphide acceptor molecules [PDF]

open access: yes, 2008
Background: Regulation of sulphur metabolism in Corynebacterium glutamicum ATCC 13032 has been studied intensively in the last few years, due to its industrial as well as scientific importance.
Albersmeier, Andreas   +5 more
core   +3 more sources

DASH: a versatile and high‐capacity gene stacking system for plant synthetic biology

open access: yesPlant Biotechnology Journal, Volume 23, Issue 9, Page 3697-3712, September 2025.
Summary DNA assembly systems based on the Golden Gate method are popular in synthetic biology but have several limitations: small insert size, incompatibility with other cloning platforms, DNA domestication requirement, generation of fusion scars, and lack of post‐assembly modification.
Chengsong Zhao   +2 more
wiley   +1 more source

Analysis of Benzoate 1,2‐Dioxygenase Identifies Shared Electron Transfer Components With DxnA1A2 in Rhizorhabdus wittichii RW1

open access: yesJournal of Basic Microbiology, Volume 65, Issue 8, August 2025.
ABSTRACT Rhizorhabdus wittichii RW1 is known for its ability to degrade polycyclic aromatic hydrocarbons, such as dibenzo‐p‐dioxin (DD) and dibenzofuran (DF). We hypothesized that the R. wittichii RW1 benzoate 1,2‐dioxygenase shares electron transfer components with the DD/DF angular dioxygenase (DxnA1A2), similar to many aromatic hydrocarbon degrading
Igor Ivanovski   +2 more
wiley   +1 more source

Evaluation of Engineering Potential in Undomesticated Microbes With VECTOR

open access: yesMicrobial Biotechnology, Volume 18, Issue 8, August 2025.
Undomesticated microbes hold vast genetic potential for synthetic biology but are difficult to engineer due to unique physiological traits and inefficient plasmid delivery. This study develops VECTOR (Versatile Engineering and Characterisation of Transferable Origins and Resistance), a high‐throughput pipeline using modular vectors to improve plasmid ...
Riley Williamson   +4 more
wiley   +1 more source

Role of methylotrophy during symbiosis between Methylobacterium nodulans and Crotalaria podocarpa [PDF]

open access: yes, 2005
Some rare leguminous plants of the genus Crotalaria are specifically nodulated by the methylotrophic bacterium Methylobacterium nodulans. In this study, the expression and role of bacterial methylotrophy were investigated during symbiosis between M ...
Dreyfus, Bernard   +7 more
core   +3 more sources

Revision and expansion of the genus Spirirestis (Tolypothrichaceae, Cyanobacteria)

open access: yesJournal of Phycology, Volume 61, Issue 4, Page 966-988, August 2025.
Abstract Recent phylogenetic analyses of members of the Tolypothrichaceae (Nostocales, Cyanobacteria) based on 16S rRNA gene sequence data have demonstrated that the soil‐inhabiting members of the family belong to a clade separate from the aquatic and subaerial members of the family.
Jeffrey R. Johansen   +14 more
wiley   +1 more source

A Serratia marcescens PigP Homolog Controls Prodigiosin Biosynthesis, Swarming Motility and Hemolysis and Is Regulated by cAMP-CRP and HexS [PDF]

open access: yes, 2013
Swarming motility and hemolysis are virulence-associated determinants for a wide array of pathogenic bacteria. The broad host-range opportunistic pathogen Serratia marcescens produces serratamolide, a small cyclic amino-lipid, that promotes swarming ...
Arena, KE   +7 more
core   +1 more source

Identification of EppR, a Second Repressor of Error‐Prone DNA Polymerase Genes in Acinetobacter baumannii

open access: yesMolecular Microbiology, Volume 124, Issue 1, Page 20-39, July 2025.
A novel TetR‐like regulator (EppR) has been identified to repress genes encoding DNA polymerase V in Acinetobacter baumannii through the direct binding of a conserved EppR motif in their promoters. EppR works with previously identified regulator UmuDAb to serve as co‐regulators of these genes. In response to DNA damage and/or environmental stress, both
Brian Nguyen   +6 more
wiley   +1 more source

A Sucrose‐Utilisation Gene Cluster Contributes to Colonisation of Horse Chestnut by Pseudomonas syringae pv. aesculi

open access: yesMolecular Plant Pathology, Volume 26, Issue 7, July 2025.
We show that a sucrose gene cluster enhances the fitness and pathogenicity of Pseudomonas syringae pv. aesculi on horse chestnut, highlighting sucrose metabolism as important for tree colonisation. ABSTRACT Pseudomonas syringae pathovar aesculi (E‐Pae) causes bleeding canker disease in the woody tissue of European horse chestnut (HC).
Sabrine Dhaouadi   +8 more
wiley   +1 more source

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