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Does p‐lactate increase in patients with GSD1 after ingesting a meal with common‐size sources of fructose and galactose? Observations from a prospective, non‐blinded, crossover pilot study [PDF]

open access: yesJIMD Reports
Ingestion of fructose and galactose may result in elevated lactate concentrations in patients with glycogen storage disease type 1 (GSD1). In this randomized cross‐over pilot study, 7 patients with GSD 1a (6) and GSD1b (1) orally consumed a common‐size ...
Camilla Diana B. Caroee, Allan M. Lund
doaj   +2 more sources

Galactose Enhances Chondrogenic Differentiation of ATDC5 and Cartilage Matrix Formation by Chondrocytes

open access: yesFrontiers in Molecular Biosciences, 2022
Galactose, an important carbohydrate nutrient, is involved in several types of cellular metabolism, participating in physiological activities such as glycosaminoglycan (GAG) synthesis, glycosylation, and intercellular recognition.
Zhongrun Yuan   +20 more
doaj   +1 more source

Experimental and Kinetic Modeling of Galactose Valorization to Levulinic Acid

open access: yesBulletin of Chemical Reaction Engineering & Catalysis, 2022
Levulinic acid, a versatile chemical building block, was derived from C6-sugar galactose using sulfuric acid as the catalyst. Galactose is monosaccharide of polysaccharides constituent that is mostly contained in third generation biomass, macro ...
Retno Ringgani   +3 more
doaj   +1 more source

Predicting Concentrations of Mixed Sugar Solutions with a Combination of Resonant Plasmon-Enhanced SEIRA and Principal Component Analysis

open access: yesSensors, 2022
The detection and quantification of glucose concentrations in human blood or in the ocular fluid gain importance due to the increasing number of diabetes patients.
Diana Pfezer   +3 more
doaj   +1 more source

Macrophage galactose lectin is critical for Kupffer cells to clear aged platelets

open access: yesJournal of Experimental Medicine, 2020
Deppermann et al. investigate how aged platelets are removed from circulation. Using intravital microscopy they observe rapid accumulation of desialylated platelets on Kupffer cells through collaboration of macrophage galactose lectin and Ashwell-Morell ...
C. Deppermann   +10 more
semanticscholar   +1 more source

Galactosylated Prodrugs: A Strategy to Improve the Profile of Nonsteroidal Anti-Inflammatory Drugs

open access: yesPharmaceuticals, 2022
Carbohydrates are one of the most abundant and important classes of biomolecules. The variety in their structures makes them valuable carriers that can improve the pharmaceutical phase, pharmacokinetics and pharmacodynamics of well-known drugs.
Federica Sodano   +8 more
doaj   +1 more source

Galactose‐modified duocarmycin prodrugs as senolytics

open access: yesAging Cell, 2020
Senescence is a stable growth arrest that impairs the replication of damaged, old or preneoplastic cells, therefore contributing to tissue homeostasis. Senescent cells accumulate during ageing and are associated with cancer, fibrosis and many age‐related
Ana Guerrero   +7 more
semanticscholar   +1 more source

Insulin Regulation of Escherichia coli Abiotic Biofilm Formation: Effect of Nutrients and Growth Conditions

open access: yesAntibiotics, 2021
Escherichia coli plays an important role in biofilm formation across a wide array of disease and ecological settings. Insulin can function as an adjuvant in the regulation of biofilm levels.
Nina Patel   +2 more
doaj   +1 more source

Galactose-Induced Skin Aging: The Role of Oxidative Stress

open access: yesOxidative Medicine and Cellular Longevity, 2020
Skin aging has been associated with a higher dietary intake of carbohydrates, particularly glucose and galactose. In fact, the carbohydrates are capable of damaging the skin's vital components through nonenzymatic glycation, the covalent attachment of ...
B. Umbayev   +5 more
semanticscholar   +1 more source

Detection of Carrageenan in Meat Products Using Lectin Histochemistry

open access: yesFoods, 2021
Carrageenan is a polysaccharide that is widely used in the food industry. Due to its water holding capacity, there is a higher risk of adulteration for economic reasons related to it.
Marie Bartlová   +3 more
doaj   +1 more source

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