Results 111 to 120 of about 356,021 (162)

Phosphatase control of cytokine-mediated overproduction of galactose-deficient IgA1, the main autoantigen in IgA nephropathy. [PDF]

J Autoimmun, 2022
Reily C, Rice T, Crossman DK, Rizk DV.
europepmc   +1 more source

Galactose-deficient IgA1 Is Involved in IgA Deposition in Renal Grafts Biopsied One Hour after Kidney Transplantation. [PDF]

Intern Med, 2023
Kuroyanagi Y, Takeda A, Kinashi H, Kuroyanagi Y, Murata M, Futamura K, Goto N, Watarai Y, Ishimoto T, Morozumi K, Ito Y.   +10 more
europepmc   +1 more source

Hydroxychloroquine sulfate for IgA nephropathy: mechanisms and therapeutic potential in improving proteinuria and alleviating disease progression - a literature review

BMC Nephrology
IgA nephropathy (IgAN), the most common form of glomerulonephritis worldwide, often progresses to chronic kidney failure within 10 to 15 years. Despite its clinical importance, effective disease-modifying therapies for IgAN remain limited. Proteinuria is
Liao Yilei, Du Yating, Fang Yaxuan, Liu Chenxuan, Cheng Tingzhu, Li Jinpu, Rao Xiangrong, Guo Chuan   +7 more
doaj   +1 more source

Glomerular deposition of galactose-deficient IgA1-containing immune complexes via glomerular endothelial cell injuries. [PDF]

Nephrol Dial Transplant, 2022
Makita Y, Suzuki H, Nakano D, Yanagawa H, Kano T, Novak J, Nishiyama A, Suzuki Y.   +7 more
europepmc   +1 more source

Glomerular Galactose-Deficient IgA1(KM55) Positive May Predict Poorer Prognosis in Coexisting Primary Membranous Nephropathy and IgA Nephropathy Patients. [PDF]

Cells, 2022
Cheng W, Wang G, Guo W, Sun L, Xu X, Dong H, Ye S, Geng Y, Cheng H.   +8 more
europepmc   +1 more source

Association of IgG co-deposition with serum levels of galactose-deficient IgA1 in pediatric IgA nephropathy

, 2012
Objective: To determine whether the absence of mesangial IgG deposits is associated with the absence of elevated blood levels of galactose-deficient IgA1 (Gd-IgA1) in pediatric patients with IgA nephropathy (IgAN).
Lau, Keith K., Julian, Bruce A., Novak, Jan, Moldoveanu, Zina, Sanders, John T., Walker, Patrick D., Gaber, Lillian, Hastings, M. Colleen, Wyatt, Robert J., Eison, T. Matthew   +9 more
core   +1 more source

Sialylation of IgG inhibits the formation of galactose-deficient IgA1-containing immune complexes and protects mesangial cells from injury in IgA nephropathy. [PDF]

BMC Nephrol, 2022
Liu Y, Li H, Yu H, Wang F, Jia J, Yan T.
europepmc   +1 more source

Serum levels of galactose-deficient IgA in children with IgA nephropathy and Henoch-Schönlein purpura

, 2007
IgA nephropathy and Henoch-Schönlein purpura nephritis (HSPN) are related diseases characterized by deposits of IgA1-containing immune complexes in the renal mesangium.
Lau, Keith K., Novak, Jan, Moldoveanu, Zina, Huang, Wen Qiang, Jeannette Y. Lee, Tomana, Milan, Wen-Qiang Huang, Ronald J. Hogg, Hogg, Ronald J., Jiri Mestecky, Robert J. Wyatt, Milan Tomana, Julian, Bruce A., Jan Novak, Zina Moldoveanu, Bruce A. Julian, Lee, Jeannette Y., Keith K. Lau, Wyatt, Robert J., Mestecky, Jiri   +19 more
core   +1 more source

Astragaloside IV Inhibits Galactose-Deficient IgA1 Secretion via miR-98-5p in Pediatric IgA Nephropathy. [PDF]

Front Pharmacol, 2021
Liu C, Li X, Shuai L, Dang X, Peng F, Zhao M, Xiong S, Liu Y, He Q.   +8 more
europepmc   +1 more source

Structural Studies of Catalysis and Processing in Galactose [PDF]

, 2007
The fungal copper containing enzyme galactose oxidase is one of the earliest examples of a protein derived radical cofactor. A covalent bond, formed between the active site cysteine and the Cc of a tyrosine act as a site for radical formation, allowing ...
Akumanyi, Nana
core