Results 161 to 170 of about 184,426 (243)

Ginsenoside Rh1 Attenuates Alzheimer's Disease‐Like Deficits by Modulating Oxidative Stress and Mitochondrial Dysfunction via SIRT1‐Related Signaling

Phytotherapy Research, EarlyView.
Rh1 attenuates oxidative stress and mitochondrial dysfunction through SIRT1‐related signaling. ABSTRACT Alzheimer's disease (AD) remains a progressive neurodegenerative disorder with limited therapeutic options. Ginsenoside Rh1 has been reported to possess neuroprotective properties, yet its specific role and underlying mechanisms in AD are not fully ...
Shi‐Lu Li, Tao Lin, Wan‐chen Zou, Ya‐jun Wang, Jing‐tian Zhang, Zi Wang, Hong‐yuan Li, Long Chen, Li‐chun Zhao, Shen Ren, Wei Li   +10 more
wiley   +1 more source

Emerging Evidence Suggests That N-Glycosylation Pathway Perturbation Has a Greater Impact than Microbial Depletion on α-Gal Antigen Biogenesis in Lone Star Tick (<i>Amblyomma americanum</i>) Salivary Glands. [PDF]

Microorganisms
Sharma SR, Karim S.
europepmc   +1 more source

Salidroside Alleviates AlCl3/D‐galactose‐Induced Alzheimer's Disease‐Like Mice Neuronal Damage and Synaptic Dysfunction Through Keap1/Nrf2/GSH Signaling Axis

Phytotherapy Research, EarlyView.
Salidroside alleviates AlCl3/D‐galactose‐induced neuronal injury and synaptic dysfunction in AD‐like mice via regulation of the Keap1/Nrf2/GSH signaling axis. ABSTRACT Alzheimer's disease (AD) is associated with glutathione (GSH) depletion and redox imbalance in the brain, contributing to hippocampal neuronal damage and synaptic dysfunction and ...
Heying Cui, Yihua Han, Yanzhu Lu, Shuhua Zheng, Ruijing Zhang, Xianjing Zhang, Zheng Nan, Xiangdan Li, Songbiao Cui, Dongyuan Xu   +9 more
wiley   +1 more source

P2X7 Receptor Antagonist A740003 Mitigates Cardiac Senescence by Inhibiting Inflammaging Through the NF-κB Pathway. [PDF]

Pharmaceuticals (Basel)
Bin Dayel AF, Alonazi AS, Alhajjari AZ, Alwakail DA, Alamin MA, Alrajeh HM, Alameen AA, Elnagar DM, Alrasheed NM.   +8 more
europepmc   +1 more source

Deciphering Branched Galactomannan Structures via Multistage Ion Mobility MS and MSn Fragmentation (Multistage IMSn)

Rapid Communications in Mass Spectrometry, EarlyView.
ABSTRACT Rationale Hemicelluloses are abundant carbohydrate components in plant cell walls. They play a crucial structural role in binding cellulose microfibrils, in addition to other biological functions. Their high structural variability directly influences their biological properties, making it important to establish a structure–function ...
Rania Benazza, Mathieu Fanuel, Hélène Rogniaux, David Ropartz   +3 more
wiley   +1 more source

Pollenless endeavour: loss of a glyoxal/galactose oxidase causes male sterility in rice. [PDF]

Plant Physiol
Sharma G.
europepmc   +1 more source

Responsive nanoheterojunctions for built‐in electric field‐promoted cascade tumor targeting and cuproptosis‐based therapy

Responsive Materials, EarlyView.
Nanoheterojunctions have been synthesized as responsive biomaterials for cascade targeting of tumor cells and mitochondria, ROS‐mediated apoptosis and Cu‐promoted cuproptosis. And drug‐device‐field integration as an advanced paradigm of tumor treatment was employed for photo‐triggered tumor cell elimination in vitro and lesion eradication in vivo ...
Zhe Liu, Yandai Lin, Xuehui Li, Fengqi Xuan   +3 more
wiley   +1 more source

Advances in galactose-based small-molecule hepatocyte-targeting probes for detecting biomarkers in hepatocellular carcinoma. [PDF]

Front Chem
Li X, Fu J, Wang M, Zhu Z.
europepmc   +1 more source

Binder Design in Extrusion‐Based 3D Printing of Electrodes: Enhancing Printability and Electrochemical Performance in Energy Storage Devices

Small, EarlyView.
Binder design plays a pivotal role in extrusion‐based 3D printing of energy storage electrodes by simultaneously governing ink printability and electrochemical performance. This review examines how diverse binder materials and design strategies are employed to enable printability while addressing key electrochemical challenges in energy storage devices,
Akesh Manimendra Badalge, Timothy J. Biddle, Huynh Tam Minh Nguyen, Eric Campbell, Munkhbayar Batmunkh, Tak Kim, Stefanie Feih, Yu Lin Zhong   +7 more
wiley   +1 more source

Apelin-13 prevents GATA4-mediated neuronal senescence by restoring autophagy through mTORC1 inhibition. [PDF]

Cell Death Dis
Han SJ, Cho JH, Lim JR, Yoon JH, Park JY, Chang HS, Kim SY, Kim HJ, Lee SG, Mun SJ, Yun JH, Chae CW, Jung YH, Han HJ.   +13 more
europepmc   +1 more source