Results 201 to 210 of about 242,958 (298)

Exploiting Activated Alkyne Chemistry for the Synthesis of Tailored Amphiphilic Janus Dendrimers with Aggregation‐Induced Emission and Their Assemblies for Cell Imaging

open access: yesChemistry – A European Journal, EarlyView.
Amphiphilic Janus dendrimers (AJDs) synthesized via activated alkyne‐hydroxyl “click” chemistry exhibit aggregation‐induced emission (AIE) properties and self‐assemble into fluorescent nanostructures, including dendrimersomes and micelles. These assemblies, with excellent biocompatibility and efficient cellular uptake, demonstrate potential for live ...
Hossein Rasoulmosaedi   +4 more
wiley   +1 more source

Honeybees fed D-galactose exhibit aging signs with changes in gut microbiota and metabolism. [PDF]

open access: yesmSystems
Zhou G   +11 more
europepmc   +1 more source

Immunological and Toxicological Assessment of Triterpenoid Saponins Bearing Lewis‐X‐ and QS‐21‐Based Trisaccharides

open access: yesChemistry – A European Journal, EarlyView.
The synthesis of betulinic acid and echinocystic acid saponins featuring QS‐21 minimal immunogenic motif is reported. These chimeric saponins, together with previously synthesized Lewis‐X‐containing triterpenoid saponins and a rhamnose‐modified saponin, were assessed for their toxicological and immunological profiles in wild‐type and/or hDC‐SIGN ...
Oscar Javier Gamboa Marin   +9 more
wiley   +1 more source

Structural Insights Into Galectin‐3 Recognition of a Selenoglycomimetic

open access: yesChemMedChem, EarlyView.
Galectin‐3, a β‐galactoside‐binding protein, plays a pivotal role in fibrosis and carcinogenesis. We explore the molecular recognition of a seleno‐digalactoside, modified with a benzyl group (SeDG‐Bn), as a potent Gal‐3 inhibitor. Using nuclear magnetic resonance and molecular dynamics simulations, we present a 3D model of the SeDG‐Bn/Gal‐3 complex ...
Maria Pia Lenza   +12 more
wiley   +1 more source

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