Results 211 to 220 of about 184,426 (243)

Conserved dimerization architecture in C‐type lectins from virus‐vector mosquitoes

The FEBS Journal, EarlyView.
C‐type lectins (CTLs) are involved in the detection of viral/microbial carbohydrates. We studied a family of soluble CTLs in the mosquito Aedes aegypti, which acts as a vector for viruses like dengue and Zika. Using crystallography, biophysics, and structure prediction approaches, we found that these proteins consistently pair together in the same ...
Mattia Bertinelli, Rupesh Balaji Jayachandran, Jack Whitehead, Cédric Leyrat, Annabel v. Clanner, Guido C Paesen, Max Renner   +6 more
wiley   +1 more source

Functional and transcriptomic analyses in Neurospora crassa reveal a crucial role for the N‐glycoprotein deglycosylation process in fungal homeostasis

The FEBS Journal, EarlyView.
In Neurospora crassa, a cytosolic GH18 endo‐β‐n‐acetylglucosaminidase (ENGase) functions as an active deglycosylating enzyme. Deletion of this severely alters tolerance to multiple stress conditions and causes extensive transcriptomic reprogramming, including upregulation of a GH20 exo‐β‐n‐acetylhexosaminidase under ER stress, indicating that N. crassa
Anastasios Samaras, Tanim Jabid Hossain, Magnus Karlsson, Georgios Tzelepis   +3 more
wiley   +1 more source

Inhibition of Mitochondrial Fission by Mdivi-1 Alleviates Doxorubicin-Induced Nephrotoxicity in a Rat Model of D-Galactose-Induced Accelerated Renal Aging. [PDF]

Biomolecules
Kobroob A, Maneechote C, Sivasinprasasn S, Chattipakorn N, Wongmekiat O.   +4 more
europepmc   +1 more source

Structural insights into xyloglucan recognition by an ABC transporter from a Gram‐positive, thermophilic bacterium

The FEBS Journal, EarlyView.
Athe_2052 is an ABC transporter substrate‐binding protein that recognizes xyloglucan heptasaccharide (XXXG), a soluble breakdown product of plant xyloglucan. The crystal structure of Athe_2052, together with binding assays and computational modeling, shows how XXXG is recognized by this sugar transporter.
Hansen Tjo, Virginia Jiang, Philip D. Jeffrey, Angela Zhu, A. James Link, Jerelle A. Joseph, Jonathan M. Conway   +6 more
wiley   +1 more source

Microplastics and IgA nephropathy: a novel environmental hypothesis of immune dysregulation. [PDF]

Ren Fail
Shah J, Wells-Gatnik W, Palmer BF, Clegg DJ.   +3 more
europepmc   +1 more source

Integrative transcriptomic and experimental analyses prioritize TPT1 as a PANoptosis-associated candidate molecular marker in sarcopenia. [PDF]

Front Cell Dev Biol
Dong S, Wang M, Liang C, Xu P, Ye Z, Yao J, Tang Z, Ou T, Zhao X, Dai X, Li Y, Ji G.   +11 more
europepmc   +1 more source

Protective Effects of Policosanol and Atorvastatin Co-Supplementation Against High-Cholesterol and High-Galactose Diet-Induced Metabolic and Organ Dysfunction in Zebrafish. [PDF]

Int J Mol Sci
Cho KH, Jeon C, Bahuguna A, Kim JE, Lee SH, Lee Y, Baek SH.   +6 more
europepmc   +1 more source

Allergenicity of α‐Gal‐Containing Products

Allergy, EarlyView.
Frederik Bloch Mangaard, Esben Eller, Per Stahl Skov, Charlotte G. Mørtz, Carsten Bindslev‐Jensen   +4 more
wiley   +1 more source

Multi-omics-guided metabolic engineering of Limosilactobacillus reuteri for high-level 3-hydroxypropionaldehyde production from glucose. [PDF]

Microb Cell Fact
Liu Z, Yin Q, Li L, Wu H, Fang Y, Cheng F, Guo T.   +6 more
europepmc   +1 more source

Dynamic Metabolomic Landscape of the Murine Brain Across Acute to Chronic Stages of <i>Borrelia garinii</i> Infection. [PDF]

Biomolecules
Zhai B, Niu Q, Yang H, Guo KF, Liu Y, Bao B, Zhou Y, Li B, Yin H, Zhang J.   +9 more
europepmc   +1 more source