Results 201 to 210 of about 184,426 (243)

Uridine Bisphosphonate-Carbagalactose: A Stabilized α-1,4-Galactosyltransferase Inhibitor. [PDF]

open access: yesOrg Lett
Guo J   +9 more
europepmc   +1 more source

IgE‐Binding Bacterial Components Not Yet Documented in the Allergen Databases and Their Allergenic Mechanisms: An EAACI Position Paper

open access: yesAllergy, EarlyView.
ABSTRACT Among bacteria that are associated with the development and/or exacerbation of allergic/atopic diseases, several have been described to produce IgE‐binding components. However, only one bacterial protein, Bac s 1, is currently listed in the official database of the World Health Organization/International Union of Immunological Societies (WHO ...
Uta Jappe   +24 more
wiley   +1 more source

A self-assembled Dendrobium polysaccharide hydrogel with anti-aging activity via the FOXO signaling pathway. [PDF]

open access: yesNat Prod Bioprospect
Zhang Y   +9 more
europepmc   +1 more source

Protective role of Galectin‐3 in prion disease through regulation of microglial PrPSc uptake

open access: yesBrain Pathology, EarlyView.
Galectin‐3 (Gal3) is induced in reactive microglia during prion disease and promotes microglial uptake of PrPSc. Gal3 deficiency reduces prion sequestration and accelerates disease progression, revealing a protective role for Gal3. Abstract Microglia constitute a major innate defense mechanism against prion infection; however, the molecular pathways ...
Natallia Makarava   +8 more
wiley   +1 more source

Purpurin Alleviates Meniscal Senescence and Osteoarthritis by Blocking the Non‐Metabolic Function of Hexokinase 2

open access: yesCell Proliferation, EarlyView.
HK2 is upregulated in osteoarthritis and accelerates disease progression via a glycolysis‐independent non‐metabolic mechanism. It recruits PRKN to degrade MYH10, reducing COL1A1 mRNA stability and inducing senescence. Purpurin disrupts this pathogenic pathway with therapeutic potential.
Zhencan Lin   +9 more
wiley   +1 more source

Blacklegged Ticks, Ixodes scapularis, Respond to Sex‐Attractant Semiochemicals of Male Deer Mice, Peromyscus maniculatus

open access: yesEntomologia Experimentalis et Applicata, EarlyView.
Ticks are obligate ectoparasites that blood‐feed on a variety of vertebrate hosts including rodents such as deer mice, Peromyscus maniculatus bairdii. Female blacklegged ticks, Ixodes scapularis—but not female lone star ticks, Amblyomma americanum, or American dog ticks, Dermacentor variabilis—were attracted to urine‐ and feces‐soiled bedding of male ...
Claire E. Gooding   +4 more
wiley   +1 more source

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