Results 231 to 240 of about 261,281 (306)

Concentration-dependent mutational scanning probes the cellular folding landscape of α-synuclein in yeast. [PDF]

Protein Sci
Noh D, Newberry RW.
europepmc   +1 more source

Brain viral reservoir seeding and neurological metabolic dysregulation in early‐life immunodeficiency virus infection

Brain Pathology, EarlyView.
Brain viral reservoirs were undetectable in neonatal SIV during the first 3 days post infection; antiretroviral therapy (ART) at 3 dpi prevented brain reservoir seeding and normalized metabolic function, highlighting the necessity of very early treatment to protect the developing CNS.
Li Ma, Robert Blair, Yao‐Zhong Liu, Xiaolei Wang, Eunice Vincent, Christopher Yu, Lara A. Doyle‐Meyers, Cissy Zhang, Ahmad Saied, Anne Le, Ronald S. Veazey, Qigui Yu, Huanbin Xu   +12 more
wiley   +1 more source

Glycolytic metabolism of CD8+ T‐cells affects susceptibility to human leukocyte antigen‐mediated abacavir‐induced hypersensitivity

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Drug hypersensitivity reactions (DHRs) associated with a specific human leukocyte antigen (HLA) allotype do not manifest uniformly in all individuals within an HLA model population. This scenario highlights the complexity of predicting drug hypersensitivity reaction risk without considering additional factors ...
Takeshi Susukida, Yuchen Sun, Noriaki Arakawa, Takuya Hirao, Tadahaya Mizuno, Shigeki Aoki, Kousei Ito, Yoshihiro Hayakawa   +7 more
wiley   +1 more source

ROS-mediated apoptosis in colon cancer cells induced by sulfated polysaccharides from Gracilaria corticata. [PDF]

PLoS One
Falihzadeh Z, Roomiani L.
europepmc   +1 more source

Abnormal cleavage patterns in equine in vitro‐produced embryos lead to higher early pregnancy loss

Equine Veterinary Journal, EarlyView.
Summary Background Despite significant advances, in vitro production (IVP) of equine embryos continues to lack standardised embryo classification criteria and is associated with increased rates of early pregnancy loss compared with in vivo‐derived blastocysts.
Soledad Martin‐Pelaez, Alejandro de la Fuente, Kazuki Takahashi, Hugo Monteiro, Mauricio Mendes, Stuart Meyers, Pouya Dini   +6 more
wiley   +1 more source

TCA cycle intermediates as an adjunct strategy for human iPSC-derived cardiomyocyte maturation. [PDF]

BBA Adv
Alagarsamy KN, Bueckert E, Gupta M, Aliani M, Dhingra S.   +4 more
europepmc   +1 more source

Ligand‐specific tuning of CLEC10A signalling strength and dendritic cell responses through engagement of different GalNAc‐containing glycan structures

The FEBS Journal, EarlyView.
The authors investigated the effects of various glycan ligands for CLEC10A, a lectin receptor expressed on dendritic cells (DCs). Monocyte‐derived DCs were stimulated with glycan‐conjugated dendrimers in combination with the TLR1/2 ligand Pam3CysK4, and responses were investigated at the mRNA and protein level.
Nadia L. van der Meijs, Remi Hatinguais, Mike de Kok, R. J. Eveline Li, Tesfay M. Godefa, Victor L. J. L. Thijssen, Yvette van Kooyk, Sandra J. van Vliet   +7 more
wiley   +1 more source

A genetic interaction between DED1 and HAT1 in Saccharomyces cerevisiae reveals a role for Hat1p in cytoplasmic RNA granule accumulation. [PDF]

G3 (Bethesda)
Panko AJ, Winters A, Rothbard NR, Hilliker AK.   +3 more
europepmc   +1 more source

Plant organelle C‐to‐U RNA editing factors can operate successfully in yeast (Saccharomyces cerevisiae) as an easily amenable eukaryotic system for their functional analysis

The FEBS Journal, EarlyView.
Plant‐type pentatricopeptide repeat proteins capable of C‐to‐U RNA editing perform faithfully when expressed in a new heterologous system, the yeast Saccharomyces cerevisiae. They were tested with constitutive and inducible expression and with a set of different solubility tags. PPR56, PPR65, and PPR78 from P.
Shyam Ramanathan, Annika Hanraths, Jingchan Xie, Mareike Schallenberg‐Rüdinger, Volker Knoop   +4 more
wiley   +1 more source

<i>Inonotus obliquus</i> Polysaccharides: Preparation, Structural Characteristics, Structure-Activity Relationships, Biological Activities and Applications. [PDF]

Nutrients
Zhang S, Zhang W, Wu X, Li S, Shi D, Li H, Liu T, Gong A.   +7 more
europepmc   +1 more source