Results 271 to 280 of about 242,958 (298)

Conformational Profile of Galactose-α-1,3-Galactose (α-Gal) and Structural Basis of Its Immunological Response. [PDF]

Chemistry
Santra G, Pantazis DA.
europepmc   +1 more source

Leveraging core enzyme structures for microbiota targeted functional regulation: Urease as an example

iMeta, EarlyView.
We present an innovative methodology that integrates core enzyme identification, protein structural characterization, regulator virtual screening, and functional validation to achieve precise microbiome functional regulation. As a proof of concept, we focused on the regulation of urea decomposition by the rumen microbiota in ruminants. This methodology
Shengguo Zhao, Huiyue Zhong, Yue He, Xiaojiao Li, Li Zhu, Zhanbo Xiong, Xiaoyin Zhang, Nan Zheng, Diego P. Morgavi, Jiaqi Wang   +9 more
wiley   +1 more source

Influence of Produced Water and Light Irradiation on the Composition of Exopolysaccharide Produced by L. amnigena Evaluated by Raman Spectroscopy. [PDF]

Biopolymers
da Silva APLT, Soares LGP, Gulberg LD, Crugeira PJL, de Almeida PF, Fernandes AU, Silveira L, Pinheiro ALB.   +7 more
europepmc   +1 more source

Single‐microbe RNA sequencing uncovers unexplored specialized metabolic functions of keystone species in the human gut

iMeta, EarlyView.
The human body is inhabited by trillions of microorganisms that play a crucial role in health and diseases. Although our understanding of the species and functional composition of the human gut microbiome is rapidly expanding, species–function heterogeneity and dynamic activities in human microecosystem niches remain unclear.
Yifei Shen, Wenxin Qu, Mengdi Song, Tianyu Zhang, Chang Liu, Xiaofeng Shi, Xinxin Xu, Jingjing Jiang, Liguo Ding, Fangyu Mo, Zheying Mao, Mingzhu Huang, Ziye Xu, Jiaye Chen, Enhui Shen, Jian Ruan, Jiong Liu, Michael P. Timko, Yu Chen, Longjiang Fan, Shufa Zheng, Yongcheng Wang   +21 more
wiley   +1 more source

An eczematous eruption with features of prurigo nodularis: An unexpected presentation of alpha-gal syndrome. [PDF]

JAAD Case Rep
Wu S, Nadelmann ER, Koschitzky M, Balagula Y, Halverstam C, Klar T.   +5 more
europepmc   +1 more source

Research progress of antibody coupling technique in targeted drug delivery

Interdisciplinary Medicine, EarlyView.
Abstract Antibody‐drug conjugates are a cutting‐edge biotechnology recently attracting wide attention in the medical field. Binding antibodies to drug molecules could deliver drugs precisely to the site of the lesion, which shows great potential in the treatment of tumors and immune diseases.
Meng Li, Tiantian Wang, Dan Tan, Mengqi Wang, Changhai Lei, Yuqing Wang, Shi Hu   +6 more
wiley   +1 more source

Diminazine protects against cardiac aging through the improvement of mitophagy and apoptosis in aging rats induced by D-galactose. [PDF]

BMC Cardiovasc Disord
Velayati E, Sarihi A, Zarei M, Komaki A, Ramezani-Aliakbari F.   +4 more
europepmc   +1 more source

Engineered strategies for the allergic disease therapy

Interdisciplinary Medicine, EarlyView.
Allergic diseases exist widely across the globe and now there are very limited therapeutics for the treatment of these diseases. In this review, we summarize the recent advances in engineering strategies including nanoemulsion and hydrogel to improve the therapeutic efficacy of allergen‐specific immunotherapy with decreased side effects and long‐term ...
Yun Tian, Xin Wu, Xiaoqi Sun, Lei Rong, Kai Han   +4 more
wiley   +1 more source

Correction for Li et al., Recurrent DNA nicks drive massive expansions of (GAA)_n repeats. [PDF]

Proc Natl Acad Sci U S A
europepmc   +1 more source

Yeast mutation rates in alternative carbon sources reflect the influence of reactive oxygen species. [PDF]

MicroPubl Biol
Thota K, Fredette-Roman JD, Sharp NP.
europepmc   +1 more source