In diabetic condition the oxygen free radical and reduced glutathione level are the important risk factor for cataract formation. The preventive effect of antioxidant and increased cellular glutathione level on cataract formation reported in experimental
H Fallah Huseini+3 more
doaj
Impact of Ig-Therasorb (R) immunoapheresis on stability of xenogeneic ex vivo porcine liver perfusion - Value of aminotransferases and flow rates for the assessment of metabolic graft viability [PDF]
Due to growing shortage of donor organs, the concept of extracorporeal pig liver perfusion in the treatment of acute liver failure has been rediscovered.
Dietz, Oliver+4 more
core +1 more source
Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq+4 more
wiley +1 more source
Targeting CYP450 modulation to decrease the risk of induced cataract in the experimental model
Background: Diabetes is one of the major causes of cataract. Some drugs prescribed for the treatment of diabetes are the modulators of CYP450, which may alter the risk of cataract.
Patel D+4 more
doaj
Role of anterior segment optical coherence tomogram in Descemet′s membrane detachment
Descemet′s membrane detachment (DD) is a rare but serious complication of intraocular surgery. In rare cases where corneal edema is severe and we may not be able to visualize DD on slit-lamp examination, anterior segment optical coherence tomogram (AS ...
Sonia Kothari+2 more
doaj +1 more source
Nanoparticles Based on Novel Carbohydrate-Functionalized Polymers
Polymeric nanoparticles can be used for drug delivery systems in healthcare. For this purpose poly(lactic-co-glycolic acid) (PLGA) and poly(ethylene glycol) (PEG) offer an excellent polymeric matrix.
Cláudia D. Raposo+2 more
doaj +1 more source
Galacto-oligosaccharides formation during manufacture of different varieties of yogurt. Stability through storage [PDF]
Galacto-oligosaccharides (GOS) have interest in the food industry due to their recognized functional properties. In this work, we studied the effect of a commercial β-galactosidase enzyme from Kluyveromyces lactis (YNL-2, GODO) and Lactobacillus ...
Bergamini, Carina Viviana+3 more
core +1 more source
Interfacial Yield Stress Response in Synthetic Mucin Solutions
The solution rheology of novel synthetic mucins mimicking natural mucin domains is studied. Like many natural mucin solutions, apparent solid‐like rheology is seen. However, no bulk structural features are found to explain it. Interfacial rheology and robust modelling reveal that this arises from molecular associations at the air–water interface ...
Sumit Sunil Kumar+7 more
wiley +1 more source
Influence of galactose cataract on erythrocytic and lenticular glutathione metabolism in albino rats
Context: Glutathione depletion has been postulated to be the prime reason for galactose cataract. The current research seeks the prospect of targeting erythrocytes to pursue the lens metabolism by studying the glutathione system.
M Jyothi, R Sanil, S Shashidhar
doaj +1 more source
Discovering transcriptional modules by Bayesian data integration [PDF]
Motivation: We present a method for directly inferring transcriptional modules (TMs) by integrating gene expression and transcription factor binding (ChIP-chip) data.
Antoniak+38 more
core +2 more sources