Results 51 to 60 of about 168,620 (305)

Beyond the Dilemmas: Design of PLA-PEG Assemblies Based on pH-Reversible Boronic Ester for the Synchronous PEG De-Shielding and Ligand Presentation to Hepatocytes

Applied Sciences, 2022
A new polymeric construct is proposed as a starting material for a liver-targeted delivery system in the present communication. The polymeric material has been designed to be sensitive to pH variations and potentially loaded with hydrophobic antitumoral ...
Carla Sardo, Carmela Tommasino, Giulia Auriemma, Tiziana Esposito, Rita Patrizia Aquino   +4 more
doaj   +1 more source

Integration of Spatiotemporal Multi‐Omics in Peach Fruit Unravels a Metabolic Niche and the Genetic Basis of Trichome‐Mediated Stress Adaptation

Advanced Science, EarlyView.
This study constructed the first spatiotemporal multi‐omics map of peach fruit and discovered a key candidate gene that synergistically regulates trichome development and drought tolerance through the jasmonic acid signaling pathway, providing insights into the coupling mechanism between development and stress resistance.
Zhixin Liu, Ke Cao, Liping Guan, Aizhi Qin, Yong Li, Zihao Zhao, Yinpeng Zhang, Yaping Zhou, Lirong Wang, Xuwu Sun   +9 more
wiley   +1 more source

Streptavidins Coordinate Biotin Sequestration and Self‐Resistance Within a Biotin‐Pathway Antibiotic Network

Advanced Science, EarlyView.
A conserved genomic region between two streptavidin genes in Streptomyces packages biosynthetic gene clusters for diverse biotin‐pathway antibiotics: acidomycin, stravidin, the new non‐proteinogenic amino acid ANDA, and the new BioA inhibitor α‐methyl‐KAPA.
Sumire Kurosawa, Jingjun Mo, Xiaotong Diao, Feng Xie, Tingting Wang, Haowen Zhao, Dalei Wu, Rolf Müller, Chengzhang Fu   +8 more
wiley   +1 more source

Crystal structures of four thioglycosides involving carbamimidothioate groups

Acta Crystallographica Section E: Crystallographic Communications
The compounds 2′,3′,4′,6′-tetra-O-acetyl-β-D-glucopyranosyl N′-cyano-N-phenylcarbamimidothioate (C22H25N3O9S, 5a), 2′,3′,4′,6′-tetra-O-acetyl-β-D-galactopyranosyl N′-cyano-N-phenylcarbamimidothioate, (C22H25N3O9S, 5b), 2′,3′,4′,6′-tetra-O-acetyl-β-D ...
Mamdouh A. Abu-Zaied, Galal A. Nawwar, Galal H. Elgemeie, Peter G. Jones   +3 more
doaj   +1 more source

A living vector field reveals constraints on galactose network induction in yeast

Molecular Systems Biology, 2017
When a cell encounters a new environment, its transcriptional response can be constrained by its history. For example, yeast cells in galactose induce GAL genes with a speed and unanimity that depends on previous nutrient conditions.
Sarah R Stockwell, Scott A Rifkin
doaj   +1 more source

Galactose-Functionalized, Colloidal-Fluorescent Nanoparticle from Aggregation-Induced Emission Active Molecule via Polydopamine Coating for Cancer Cell Targeting

, 2018
Aggregation-induced emission (AIE) active molecules emerge as new generation fluorescent probes, and their transformation to functional nanoparticle can greatly extend the application potential.
Kuheli Mandal (2399146), Nikhil R. Jana (1268586)   +1 more
core   +1 more source

Trophic Diversity in Duckweed: Mixotrophy, More Than the Sum of its Extremes

Advanced Science, EarlyView.
In the context of rising DOC in aquatic environments, mixotrophic duckweed may impact carbon cycling by acting as either a carbon sink, as they absorb CO2 through photosynthesis, or a carbon source, as they release CO2 through respiration of absorbed DOC, which depends on DOC concentration, light availability, temperature, and other environmental ...
Zuoliang Sun, Yan Chen, Fajun Li, Xuyao Zhao, Qingxiang Han, Hongwei Hou   +5 more
wiley   +1 more source

The effect of Herbal medicine Silybum marianum (L.) Gaertn. seed extract on galactose induced cataract formation in rat

Journal of Medicinal Plants, 2004
In diabetic condition the oxygen free radical and reduced glutathione level are the important risk factor for cataract formation. The preventive effect of antioxidant and increased cellular glutathione level on cataract formation reported in experimental
H Fallah Huseini, AB Zaree, A Babaei Zarch, R Heshmat   +3 more
doaj  

Síntese e caracterização de novos complexos de cobre(ii) e zinco(ii) de relevância bioinorgânica [PDF]

, 2008
TCC (graduação) - Universidade Federal de Santa Catarina. Centro de Ciências Físicas e Matemáticas. Curso de Química.Dentre as metaloenzimas de cobre pode-se citar a galactose oxidase, responsável pela oxidação de uma gama de álcoois primários a aldeídos
PASSOS, Fernando dos
core  

A Microgel Platform Enables Site‐Specific Intestinal Delivery of Lactoferrin, Improving its Bioavailability for Targeted Alleviating Liver Injury and Colitis

Advanced Science, EarlyView.
This work first time reports an eco‐friendly desert plant food‐based polysaccharide ASKP microgels which have intestinal site‐specific release properties which can achieve small‐intestine or colon targeting capability via different cross‐linking chemistry.
Huiling Yan, Yixuan Li, Shanan Chen, Pengcheng Du, Kaiwen Wu, Hui Zhang, Kasper Hettinga, Lina Zhang, Gergely Toldi, Fazheng Ren, Yuan Li   +10 more
wiley   +1 more source