Results 111 to 120 of about 4,197 (261)

Peptide‐based antibacterial nanoplatforms: Design principles, stimuli‐regulated behaviors, and applications

Responsive Materials, EarlyView.
Peptide‐based antibacterial nanoplatforms, encompassing self‐assembled peptides and peptide‐engineered inorganic, polymeric, and lipid nanocarriers, are systematically reviewed. The article highlights design principles and stimuli‐responsive regulation for improving peptide stability, delivery efficiency, and antibacterial performance.
Peng Tan, Chenlong Zhou, Shuaikang Yang, Zhenduo Chen, Guanghui Zhao, Qi Tang, Haoyu Yan, Feng Li, Xi Ma   +8 more
wiley   +1 more source

Natural antibacterial silk produced by feeding silkworms with human hair derived carbon dots

Responsive Materials, EarlyView.
Blue‐fluorescent and antibacterial carbon dots, prepared from Crinis Carbonisatus (a traditional Chinese medicine made by calcinating human hair), are fed to silkworms to produce multifunctional silk, which retains its inherent mechanical properties, exhibits blue fluorescence, possesses antibacterial activity, and promotes the wound healing of rats as
Zhao‐Fan Wu, Xiao‐Feng Shi, Xiao‐Xiao Luo, Xi‐Rong Zhang, Yuan‐Qing Mao, Huan‐Ming Xiong   +5 more
wiley   +1 more source

A GH42 β‑Galactosidase from the Human Isolate <i>Bifidobacterium breve</i> DSM 20213: Biochemical and Transgalactosylation Properties Reveal the Potential for Galacto-oligosaccharides Synthesis. [PDF]

ACS Omega
Vu-Le KT, Phirom-On K, Sripattanakul S, Chu DB, Hann S, Blaukopf M, Suetzl L, Oostenbrink C, Haltrich D, Nguyen TH.   +9 more
europepmc   +1 more source

Osmotic Remodeling of Extracellular Vesicles for Precision Nanomedicine

Small, EarlyView.
Hypotonic lysis in bidistilled water is used to remodel B lymphocyte–derived extracellular vesicles into cargo‐depleted, structurally preserved nanovesicles. The process reduces intraluminal proteins and nucleic acids, reshapes membrane composition, and enhances tumor‐cell uptake in vitro, while allowing proof‐of‐concept reloading with exogenous agents,
Francesca Susa, Lorenzo Arnaboldi, Veronica De Giorgis, Marco Ghirimoldi, Elettra Barberis, Marco Brucale, Francesco Valle, Mario Malerba, Marta Vallino, Angelo Musicò, Roberto Frigerio, Alessandro Gori, Vera Mugoni, Claudia Voena, Roberto Pisano, Fabrizio Pirri, Silvia Arpicco, Marcello Manfredi, Tania Limongi   +18 more
wiley   +1 more source

Unveiling the Transgalactosylation Switch of a GH42 β‑Galactosidase from the Infant Isolate <i>Bifidobacterium breve</i> DSM20213. [PDF]

ACS Catal
Phirom-On K, Vu-Le KT, Sützl L, Lehner B, Whelan D, Guerent L, Pasini I, Schuh M, de Ruiter A, Blaukopf M, Haltrich D, Oostenbrink C, Nguyen TH.   +12 more
europepmc   +1 more source

Epac1 Alleviates Senescence in Auditory Hair Cells via the Ferroptosis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objectives The aim of this study was to investigate the changes in Epac1 and ferroptosis‐related proteins in aged mice and the House Ear Institute‐Organ of Corti 1 (HEI‐OC1) cells, with the goal of elucidating their potential role in age‐related hearing loss. Methods The expression of Epac1 in the cochlea of C57BL/6J mice was examined by using
Wen‐Jun An, Chen‐Yu Xu, Meng‐Ya Shen, Xiao‐Tao Guo, Chun‐Chen Pan, Jing‐Wu Sun, Xiao‐Min Tang, Jia‐Qiang Sun   +7 more
wiley   +1 more source

Microbial and Metabolic Correlates of Endometrial Dysfunction in Polycystic Ovary Syndrome: A Translational Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective Women with polycystic ovary syndrome (PCOS) exhibit a substantially increased risk of miscarriage, yet the underlying mechanisms remain inadequately understood. This study aimed to investigate whether specific gut microbial dysbiosis and metabolic disturbance are associated with and may potentially contribute to endometrial ...
Mengyu Jing, Xi Chen, Meiyan Jiang, Huiya Fang, Xiaoming Zhu, Xuejing Jin, Yonghui Jiao, Ningning Hou, Weiwei Gong, Aixia Liu   +9 more
wiley   +1 more source

Discovery and Preliminary Characterization of Lactose-Transforming Enzymes in <i>Ewingella americana</i> L47: A Genomic, Biochemical, and In Silico Approach. [PDF]

Int J Mol Sci
Rivero K, Valenzuela R, Rivero I, General P, Neira N, Contreras F, Alzate-Morales J, Muñoz-Villagrán C, Vera C, Arenas-Salinas M, Arenas F.   +10 more
europepmc   +1 more source

Amphibian‐Derived Peptide OA‐AL14 Alleviates UVB‐Induced Skin Photoaging via Autophagy Activation Mediated by the AMPK/mTOR Pathway

Integrative Zoology, EarlyView.
The schematic diagram illustrates that the amphibian‐derived peptide OA‐AL14 protects against UVB‐induced skin photoaging through a dual mechanism: activating the Nrf2 pathway to counteract oxidative stress and modulating the AMPK/mTOR axis to induce protective autophagy. ABSTRACT Skin photoaging, primarily driven by ultraviolet B (UVB) radiation, is a
Ying Peng, Yutong Wu, Zhe Fu, Zijian Kang, Qiuye Jia, Wenbi Zhao, Ziyi Wang, Yuexi Liu, Ruijie Zhang, Yuansheng Li, Zeqiong Ru, Wenrou Su, Naixin Liu, Yilin Li, Saige Yin, Ying Wang, Xinwang Yang   +16 more
wiley   +1 more source

Immobilized Enzymes for ABO-Independent Blood Cell Transfusions. [PDF]

Chembiochem
Möller C, Pohlschröder F, Wesche J, Schmiade P, Baselau M, Wende K, Stloukalová B, Böttcher D, Greinacher A, Bornscheuer UT, Terholsen H, Aurich K.   +11 more
europepmc   +1 more source