Results 141 to 150 of about 18,981 (340)

Transcriptional repression of SOX2 by p53 in cancer cells regulates cell identity and migration

open access: yesInternational Journal of Cancer, EarlyView.
What's New? SOX2 is one of the key developmental genes with a reported altered expression in many tumors. The mechanisms underlying SOX2 regulation in cancer, however, remain elusive. This study shows that TP53 transcriptionally regulates SOX2 through binding to its promoter and the SRR2 enhancer.
Patricia Lado‐Fernández   +13 more
wiley   +1 more source

History, synthesis, properties, applications and regulatory issues of prebiotic oligosaccharides [PDF]

open access: yes, 2014
In this chapter, the health promoting effects of carbohydrate prebiotics are addressed. A brief description of their synthesis, thermo-physical properties, mechanisms of action, technological applications and current regulatory issues are ...
Costa, Maria do Céu   +4 more
core  

Construction of Reporter Phage T4::Nluc and Its Application in the Detection of Escherichia coli in Urinary Tract Infections

open access: yesiLABMED, EarlyView.
A reporter phage T4::Nluc was constructed using the CRISPR/Cas9 system combined with homologous recombination and was applied for the detection of clinical Escherichia coli in urinary tract infections (UTIs). T4::Nluc exhibited superior sensitivity and specificity, and had a short detection time, making it a powerful tool for diagnosing UTIs.
Zhiyun Hao   +6 more
wiley   +1 more source

Maternal gut microbiota‐derived daidzein prevents osteoporosis in female offspring following prenatal prednisone exposure

open access: yesiMeta, EarlyView.
Prenatal prednisone therapy (PPT)/prenatal prednisone exposure (PPE) induces long bone dysplasia, reduced peak bone mass (PBM), and increased osteoporosis susceptibility in female offspring. Maternal gut microbiota metabolite daidzein (DAI) mediates PPE‐induced osteoporosis susceptibility in female adult offspring.
Chi Ma   +13 more
wiley   +1 more source

Development and sensory evaluation of soy milk based yoghurt

open access: yesArchivos Latinoamericanos de Nutrición, 2001
Yoghurts were prepared by fermentation of soy milk using a mixed starter culture containing Lactobacillus bulgaricus and Streptococcus thermophilus. Soy milk at 9(0) Brix was homogenised under pressure (17 MPa) and fermented with and without addition of ...
C . S Fávaro Trindade   +4 more
doaj  

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