Division of the large and multifunctional glycoside hydrolase family 2: high functional specificity and biochemical assays in the uncharacterized subfamilies. [PDF]
Lebreton A+9 more
europepmc +1 more source
Towards an understanding of the enzymatic degradation of complex plant mannan structures. [PDF]
Mafa MS, Malgas S.
europepmc +1 more source
Cell‐Surface LAMP1 is a Senescence Marker in Aging and Idiopathic Pulmonary Fibrosis
We have validated the selective upregulation of LAMP1 in SEN in culture, and the percentage of Lamp1+ cells increases in various tissues with age, as well as in fibrotic lungs following BLM instillation. The RNA‐Sequencing analysis of the Lamp1‐enriched populations confirmed the enrichment of senescence‐related genes.
Gabriel Meca‐Laguna+8 more
wiley +1 more source
Advances in Liposomal Drug Delivery: Multidirectional Perspectives on Overcoming Biological Barriers. [PDF]
Sobol Ż+2 more
europepmc +1 more source
Tissue fractionation studies. 15. Intracellular distribution and properties of β-N-acetylglucos-aminidase and β-galactosidase in rat liver [PDF]
OZ Sellinger+4 more
openalex +1 more source
HGPS patient‐derived cortical organoids exhibit progerin accumulation, nuclear abnormalities, and increased senescence in rosette structures, leading to impaired neuronal differentiation and altered gene expression. ABSTRACT Hutchinson‐Gilford progeria syndrome (HGPS) is a rare genetic disorder characterized by premature aging and primarily caused by ...
Seeun Jeon+6 more
wiley +1 more source
Carbohydrate-active enzymes from Akkermansia muciniphila break down mucin O-glycans to completion. [PDF]
Bakshani CR+11 more
europepmc +1 more source
CD38‐Targeting Peptide Vaccine Ameliorates Aging‐Associated Phenotypes in Mice
Shangcheng Yu et al. revealed that CD38‐targeting peptide vaccine ameliorated aging‐associated physical and cognitive phenotypes in mice. CD38‐vaccine selectively depletes CD38+ myeloid cells, improves glucose tolerance, and enhances oxygen consumption.
Shangcheng Yu+10 more
wiley +1 more source
Recombinant production of Paenibacillus wynnii β-galactosidase with Komagataella phaffii. [PDF]
Bechtel A+5 more
europepmc +1 more source
Novel Microbial Enzymes with Industrial Applications. [PDF]
González-Siso MI, Becerra M.
europepmc +1 more source