Results 171 to 180 of about 14,424 (294)

Division of the large and multifunctional glycoside hydrolase family 2: high functional specificity and biochemical assays in the uncharacterized subfamilies. [PDF]

open access: yesBiotechnol Biofuels Bioprod
Lebreton A   +9 more
europepmc   +1 more source

Cell‐Surface LAMP1 is a Senescence Marker in Aging and Idiopathic Pulmonary Fibrosis

open access: yesAging Cell, EarlyView.
We have validated the selective upregulation of LAMP1 in SEN in culture, and the percentage of Lamp1+ cells increases in various tissues with age, as well as in fibrotic lungs following BLM instillation. The RNA‐Sequencing analysis of the Lamp1‐enriched populations confirmed the enrichment of senescence‐related genes.
Gabriel Meca‐Laguna   +8 more
wiley   +1 more source

Patient‐Derived Cortical Organoids Reveal Senescence of Neural Progenitor Cells in Hutchinson‐Gilford Progeria Syndrome

open access: yesAging Cell, EarlyView.
HGPS patient‐derived cortical organoids exhibit progerin accumulation, nuclear abnormalities, and increased senescence in rosette structures, leading to impaired neuronal differentiation and altered gene expression. ABSTRACT Hutchinson‐Gilford progeria syndrome (HGPS) is a rare genetic disorder characterized by premature aging and primarily caused by ...
Seeun Jeon   +6 more
wiley   +1 more source

Carbohydrate-active enzymes from Akkermansia muciniphila break down mucin O-glycans to completion. [PDF]

open access: yesNat Microbiol
Bakshani CR   +11 more
europepmc   +1 more source

CD38‐Targeting Peptide Vaccine Ameliorates Aging‐Associated Phenotypes in Mice

open access: yesAging Cell, EarlyView.
Shangcheng Yu et al. revealed that CD38‐targeting peptide vaccine ameliorated aging‐associated physical and cognitive phenotypes in mice. CD38‐vaccine selectively depletes CD38+ myeloid cells, improves glucose tolerance, and enhances oxygen consumption.
Shangcheng Yu   +10 more
wiley   +1 more source

Recombinant production of Paenibacillus wynnii β-galactosidase with Komagataella phaffii. [PDF]

open access: yesMicrob Cell Fact
Bechtel A   +5 more
europepmc   +1 more source

Novel Microbial Enzymes with Industrial Applications. [PDF]

open access: yesMicroorganisms, 2023
González-Siso MI, Becerra M.
europepmc   +1 more source

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