Results 191 to 200 of about 4,197 (261)

Synthesis of an N-Galactosyl Norbornane Aziridine and its Potent Mixed Inhibition of Aspergillus oryzae β-Galactosidase. [PDF]

Chembiochem
McCormack A, Gavin R, Bols M, Murphy PV.
europepmc   +1 more source

Fragmentation of Vancoresmycin Reveals a Strong Dependence on Global Molecular Architecture for Antibacterial Activity

ChemMedChem, Volume 21, Issue 15, 14 August 2026.
Fragmentation of the natural product vancoresmycin reveals an essential role of global architecture for biological potency. Vancoresmycin is a structurally complex tetramic‐acid‐containing natural product with potent activity against Gram‐positive bacteria, yet its structure–activity relationships remain poorly defined.
Max Schönenbroicher, Florian Heppner, Maximilian Seul, Simon Morgenschweis, Aia Ali Abdelrahman, Eva Fahr, Niklas Holstein, Anna Müller, Dirk Menche   +8 more
wiley   +1 more source

Enzymes for production of whey protein hydrolysates and other value-added products. [PDF]

Appl Microbiol Biotechnol
Irazoqui JM, Santiago GM, Mainez ME, Amadio AF, Eberhardt MF.   +4 more
europepmc   +1 more source

FUCA2 Sustains AKT Signaling and Suppresses Senescence by Antagonizing FUT3‐Mediated ErbB3 Fucosylation in Lung Adenocarcinoma

Advanced Science, Volume 13, Issue 44, 7 August 2026.
ABSTRACT While targeted therapies have improved outcomes in lung adenocarcinoma (LUAD), many patients still lack targetable mutations. Here, we identified alpha‐L‐fucosidase 2 (FUCA2) as a crucial driver of LUAD by preventing cellular senescence. Mechanistically, through the restriction of fucosyltransferase 3 (FUT3)‐mediated α‐1,3‐fucosylation of ...
Lu Chen, Jintao Guo, Fei Li, Mingjie Gao, Runyang Li, Zhaozhang Huang, Yaolin Zheng, Chunyi Gao, Jihuan Hou, Qiang Yu, Bowen Zheng, Xuemei Chen, Wenqing Zhang, Xiaoting Hong, Yali Zheng, Daxuan Wang, Qiyuan Li, Tianhui Hu, Yan‐yan Zhan   +18 more
wiley   +1 more source

Mucin-driven ecological interactions in an in vitro synthetic community of human gut microbes. [PDF]

Glycobiology
Berkhout MD, Ioannou A, de Ram C, Boeren S, Plugge CM, Belzer C.   +5 more
europepmc   +1 more source

Targeting Golgi–STING Signaling to Reprogram Innate and Adaptive Immunity for the Treatment of Implant‐Associated Infections

Advanced Science, Volume 13, Issue 43, 3 August 2026.
This study presents an ultrasound‐responsive nanoplatform, CS‐BT@MZ@NEs, with a BaTiO3/Mn‐Zif‐8 core and a chondroitin sulfate coating for Golgi targeting. By leveraging neutrophil hitchhiking, it enables targeted delivery to infection sites. Under ultrasound stimulation, CS‐BT@MZ@NEs generates ROS and modulates Golgi pH to activate cGAS–STING ...
Shicheng Huo, Naifeng Zhu, Zhuocheng Lyu, Yifei Liu, Zhenjiang Xu, Chun Zhou, Yaochao Zhao, Changgui Shi   +7 more
wiley   +1 more source

Task shifting from general practitioners to nurses and the association with patient flow and resource use in out-of-hours primary care clinics: a descriptive register-based study. [PDF]

Scand J Prim Health Care
Bomholt KB, Nebsbjerg MA, Vestergaard CH, Mygind A, Burau V, Christensen MB, Huibers L.   +6 more
europepmc   +1 more source

Comparative Genomic Analysis of Lactiplantibacillus plantarum: Insights into Its Genetic Diversity, Metabolic Function, and Antibiotic Resistance. [PDF]

Genes (Basel)
Li R, Bi C.
europepmc   +1 more source

Bacterial pathogen deploys the iminosugar glycosyrin to manipulate plant glycobiology. [PDF]

Science
Sanguankiattichai N, Chandrasekar B, Sheng Y, Hardenbrook N, Tabak WWA, Drapal M, Kaschani F, Grünwald-Gruber C, Krahn D, Buscaill P, Yamamoto S, Kato A, Nash R, Fleet G, Strasser R, Fraser PD, Kaiser M, Zhang P, Preston GM, van der Hoorn RAL.   +19 more
europepmc   +1 more source

Mannans as Multifunctional Biopolymers: Structure, Properties, and Applications in Health and Industry. [PDF]

Polymers (Basel)
Karimi I, Mohammed LJ, Amshawee AM, Makki NF, Nazari K, Schiöth HB.   +5 more
europepmc   +1 more source