Results 191 to 200 of about 18,981 (340)

Requirements for Macromolecular Synthesis in the Establishment of β-Galactosidase Repression in Zygotes [PDF]

, 1968
John H. Caster, Norman E. Melechen
openalex   +1 more source

BRD4/MAP2K7/PGF Signaling Axis Promotes Senescence and Extracellular Matrix Metabolism of Nucleus Pulposus Cells in Intervertebral Disk Degeneration

Aging Cell, EarlyView.
This study identifies BRD4 as a key regulator in intervertebral disk degeneration (IDD), linking its upregulation to NP cell senescence and disrupted ECM metabolism through the BRD4/MAP2K7/PGF signaling cascade, offering a potential therapeutic target for IDD treatment.
Guangzhi Zhang, Lei Li, Zhili Yang, Zhenyu Cao, Xuchang Hu, Yonggang Wang, Xuewen Kang   +6 more
wiley   +1 more source

Identification and Protein Engineering of Galactosidases for the Conversion of Blood Type B to Blood Type O. [PDF]

Chembiochem
Möller C, Terholsen H, Schmöker O, Lê TLA, Wesche J, Schmiade P, Eppendorfer E, Rimkus N, Girbardt B, Böttcher D, Palm GJ, Hoppen J, Lammers M, Greinacher A, Aurich K, Bornscheuer UT.   +15 more
europepmc   +1 more source

Linkage-specific α-D-galactosidases from Trichomonas foetus: Characterisation of the blood-group B-destroying enzyme as A 1,3-α-galactosidase and the blood-group P1-destroying enzyme as A 1,4-α-galactosidase [PDF]

, 1975
Morgan, W.T.J., Watkins, Winifred M., Yates, A.D.   +2 more
core   +1 more source

THE GENETIC BASIS OF HYPER-SYNTHESIS OF ß-GALACTOSIDASE [PDF]

, 1963
Tadao Horiuchi, Sumiko Horiuchi, Aaron Novick   +2 more
openalex   +1 more source

Compressive Forces Induce Epigenetic Activation of Aged Human Dermal Fibroblasts Through ERK Signaling Pathway

Aging Cell, EarlyView.
Direct activation and rejuvenation of aged fibroblasts through the application of mechanical forces in a 3D spheroid culture model. The ERK signaling pathway was revealed as a key underlying mechanism. ABSTRACT Age‐related changes in human dermal fibroblasts (HDFs) contribute to impaired wound healing and skin aging.
Hui Liu, Luezhen Yuan, Lucrezia Baldi, Trinadha Rao Sornapudi, G. V. Shivashankar   +4 more
wiley   +1 more source

Prebiotic Effects of α- and β-Galactooligosaccharides: The Structure-Function Relation. [PDF]

Molecules
Ignatova I, Arsov A, Petrova P, Petrov K.   +3 more
europepmc   +1 more source

Age‐Dependent Regulation of Hippocampal Inflammation by the Mitochondrial Translocator Protein in Mice

Aging Cell, EarlyView.
The role of mitochondrial translocator protein (TSPO) in hippocampal inflammation is age‐dependent, with TSPO deletion drastically exacerbating inflammation in aged mice, while dampening it in young mice. This TSPO–aging interaction was linked to NF‐kβ and interferon regulatory transcriptional networks. TSPO deletion exacerbated age‐dependent depletion
Kei Onn Lai, Jia Hui Wong, Nevin Tham, Lauren Fairley, Roshan Ratnakar Naik, Yulan Wang, Sarah R. Langley, Anna M. Barron   +7 more
wiley   +1 more source

Diversity and enzymatic activity of Polish beehive products microbiota, and characterization of a novel β-galactosidase from Paenibacillus sp. 8. [PDF]

Sci Rep
Rosińska A, Wanarska M, Kozłowska-Tylingo K, Jurkowski M.   +3 more
europepmc   +1 more source

Structural insight into the hydrolase and synthase activities of an alkaline α-galactosidase from Arabidopsis from complexes with substrate/product. [PDF]

Acta Crystallogr D Struct Biol, 2023
Chuankhayan P, Lee RH, Guan HH, Lin CC, Chen NC, Huang YC, Yoshimura M, Nakagawa A, Chen CJ.   +8 more
europepmc   +1 more source