Results 191 to 200 of about 14,424 (294)

BIOSYNTHESIS OF β-D-GALACTOSIDASE CONTROLLED BY PHAGE-CARRIED GENES. I. INDUCED β-D-GALACTOSIDASE BIOSYNTHESIS AFTER TRANSDUCTION OF GENE z ⁺ BY PHAGE [PDF]

, 1961
Helen R. Revel, S. E. Luria, Boris Rotman   +2 more
openalex   +1 more source

Senescence Alters Antimicrobial Peptide Expression and Induces Amyloid‐β Production in Retinal Pigment Epithelial Cells

Aging Cell, EarlyView.
Healthy RPE cells produce AMPs and AMP precursors, including amyloid precursor protein (APP) and chemerin, and protect the neuroretina from blood‐borne pathogens and maintain homeostasis. When RPE cells undergo senescence, the antibacterial activity declines, and APP undergoes amylogenesis, leading to Aβ deposition.
Jian Liu, Caijiao Yi, Jinyan Qi, Xuexue Cui, Xiangling Yuan, Wen Deng, Mei Chen, Heping Xu   +7 more
wiley   +1 more source

Quaternary stabilization of a GH2 β-galactosidase from the psychrophile A. ikkensis, a flexible and unstable dimeric enzyme. [PDF]

Protein Sci
Nowak JS, Kruuse N, Rasmussen HØ, Tian P, Astono J, Schultz-Nielsen S, Thøgersen MS, Stougaard P, Pedersen JS, Otzen DE.   +9 more
europepmc   +1 more source

Lysis of Escherichia coli by Ethylenediaminetetraacetate and Phospholipases as Measured by β-Galactosidase Activity [PDF]

, 1967
Milton W. Slein, Gerald F. Logan
openalex   +1 more source

Aging Adipose‐Derived Mesenchymal Stem Cells, Cultured on a Native Young Extracellular Matrix, Are Protected From Senescence and Apoptosis Along With Increased Expression of HLA‐DR and CD74 Associated With PI3K Signaling

Aging Cell, EarlyView.
The maintenance of aging mesenchymal stem cells (MSCs) on extracellular matrix synthesized by human amniotic fluid‐derived pluripotent stem cells (ECM Plus), a young microenvironment, remarkably restored their quantity and quality along with up‐regulating HLA‐DR and CD74.
Aaron O. Gonzalez, Parveez A. Abdul Azees, Jerry P. Chen, Milos Marinkovic, Brian Cao, Ting Liang, Peiqing Hu, Chih‐Ko Yeh, David D. Dean, Yidong Bai, Xiao‐Dong Chen   +10 more
wiley   +1 more source

Activity-based metaproteomics driven discovery and enzymological characterization of potential α-galactosidases in the mouse gut microbiome. [PDF]

Commun Chem
Jiang J, Czuchry D, Ru Y, Peng H, Shen J, Wang T, Zhao W, Chen W, Sui SF, Li Y, Li N.   +10 more
europepmc   +1 more source

L‐Tryptophan Produced by Bifidobacterium pseudocatenulatum NCU‐08 Delays Aging in SAMP8 Mice by Activating the Sirt1/P53/P21/Rb Signaling Pathway

Aging Cell, EarlyView.
Bifidobacterium pseudocatenulatum NCU‐08, isolated from the feces of centenarians, facilitated the entry of L‐tryptophan into hippocampal neurons of SAMP8 mice, where it was metabolized into NAD+. The increased NAD+ levels activated Sirt1 protein, thereby suppressing the expression of senescence‐associated proteins P53, P21, and Rb, ultimately delaying
Tangchang Xu, Xiaoyun Wu, Yifei Zhang, Yujie Cai, Xinfeng Zhang, Qingwei Zeng, Jie Luo, Jing Wei, Tingtao Chen   +8 more
wiley   +1 more source

Characterization of glycoside hydrolases involved in xyloglucan degradation in the thermophilic bacterium Thermotoga maritima. [PDF]

Sci Rep
Kawai Y, Kameyama A, Sakuraba H, Matsuzawa T.   +3 more
europepmc   +1 more source

Regulation of Gratuitous -Galactosidase Synthesis in Aerobacter Aerogenes during an Adaptive Process

, 1969
Nigel G. J. Richards
openalex   +1 more source

Senescent Microglia Mediate Neuroinflammation‐Induced Cognitive Dysfunction by Selective Elimination of Excitatory Synapses in the Hippocampal CA1

Aging Cell, EarlyView.
In the CA1, microglia are activated to be responsible for synaptic pruning. However, LPS induces a senescent phenotype in microglia, characterized by the elevated levels of p16, as well as the production of SASPs. These senescent microglia mediate the removal of excitatory synapses selectively, resulting in dendritic spine loss and LTP impairment ...
Kai Liu, Di Fan, Hai‐peng Wu, Xiao‐yi Hu, Qiu‐li He, Xin‐miao Wu, Cui‐na Shi, Jian‐jun Yang, Mu‐huo Ji   +8 more
wiley   +1 more source