Results 221 to 230 of about 18,981 (340)

SQSTM1/p62 Orchestrates Skin Aging via USP7 Degradation

Aging Cell, EarlyView.
p62 exhibits diminished expression in aging skin and senescent cells. p62 serves to inhibit the accumulation of USP7 during senescence induction. The Tyr‐67 residue within the PB1 domain or Gln‐418 within the UBA domain of p62 forms a hydrogen bond with Ala‐993 of the Ubl5 domain of USP7.
Liu Chen, Xiaoping Wang, Yuchen Wang, Qingxin Yao, Yunyao Liu, Yongcheng Zhu, He Huang, Hedan Yang, Yin Yang, Yuan He, Lei Qiang   +10 more
wiley   +1 more source

Enzymes for production of whey protein hydrolysates and other value-added products. [PDF]

Appl Microbiol Biotechnol
Irazoqui JM, Santiago GM, Mainez ME, Amadio AF, Eberhardt MF.   +4 more
europepmc   +1 more source

Activity of β-galactosidase in homogenates and isolated microvilli fraction of jejunal mucosa from suckling rats [PDF]

, 1965
O. Koldovský, R. Noack, George H. Schenk, V. Jirsová, A. Heringová, H. Braná, Frank Chytil, M Fridrich   +7 more
openalex   +1 more source

TFEB Orchestrates Stress Recovery and Paves the Way for Senescence Induction in Human Dermal Fibroblasts

Aging Cell, EarlyView.
TFEB dynamics during oxidative stress‐induced premature senescence. The tBHP treatment undermines GSH‐dependent antioxidant mechanisms, leading to increased ROS production and lysosomal damage. In the stress phase, we observed the concomitant inhibition of Akt along with activation of AMPK, together leading to mTOR inhibition and subsequent ...
Lena Guerrero‐Navarro, Pablo Monfort‐Lanzas, Vinzenz Krichbaumer, Mariana E. G. De Araújo, Jlenia Monfregola, Lukas A. Huber, Andrea Ballabio, Pidder Jansen‐Dürr, Maria Cavinato   +8 more
wiley   +1 more source

Quaternary stabilization of a GH2 β-galactosidase from the psychrophile A. ikkensis, a flexible and unstable dimeric enzyme. [PDF]

Protein Sci
Nowak JS, Kruuse N, Rasmussen HØ, Tian P, Astono J, Schultz-Nielsen S, Thøgersen MS, Stougaard P, Pedersen JS, Otzen DE.   +9 more
europepmc   +1 more source

Editorial: Carbon allocation, volume II. [PDF]

Front Plant Sci, 2023
Tanvir R, Gibson SI, Wurtele ES, Li L.
europepmc   +1 more source

Carbohydrases of the rumen ciliate Epidinium ecaudatum (Crawley). 2. α-Galactosidase and isomaltase [PDF]

, 1963
RW BAILEY, BH HOWARD
openalex   +1 more source

TLR7 Mediates HIV‐1 Tat‐Induced Cellular Senescence in Human Astrocytes

Aging Cell, EarlyView.
Once internalized into endolysosomes, HIV‐1 Tat interacts and activates TLR7, causing endolysosome damage. Such interaction between HIV‐1 Tat and TLR7 also leads to a senescence‐like phenotype in astrocytes, including cell cycle arrest, elevated levels of p21 and p16 proteins, increased SA‐β‐gal activity, and enhanced secretion of SASP factors ...
Neda Rezagholizadeh, Gaurav Datta, Wendie A. Hasler, Erica C. Nguon, Elise V. Smokey, Xuesong Chen   +5 more
wiley   +1 more source

Activity-based metaproteomics driven discovery and enzymological characterization of potential α-galactosidases in the mouse gut microbiome. [PDF]

Commun Chem
Jiang J, Czuchry D, Ru Y, Peng H, Shen J, Wang T, Zhao W, Chen W, Sui SF, Li Y, Li N.   +10 more
europepmc   +1 more source

Novel Microbial Enzymes with Industrial Applications. [PDF]

Microorganisms, 2023
González-Siso MI, Becerra M.
europepmc   +1 more source