Results 221 to 230 of about 14,424 (294)

Foxg1 and Retinoic Acid Signaling Regulate Zonal Patterning in the Developing Olfactory Epithelium

open access: yesDevelopment, Growth &Differentiation, EarlyView.
ABSTRACT Odor information processing begins in the olfactory epithelium (OE), which in mice is spatially divided into two zones: the dorsomedial zone (D‐zone), responsible for innate aversive behaviors, and the ventrolateral zone (V‐zone), associated with learning‐dependent behaviors.
Anzu Kuriyama, Carina Hanashima
wiley   +1 more source

Saccharomyces cerevisiae Mub1, a substrate adaptor of E3 ubiquitin ligase Ubr2, modulates sensitivity to cell wall stressors through multiple transcription factors

open access: yesThe FEBS Journal, EarlyView.
We show that Mub1 links cell wall robustness with the ubiquitin‐proteasome system. As an adaptor protein of the E3 ubiquitin ligase Ubr2, it facilitates the ubiquitination of various transcription factors, including Mcm1 and Swi4. Yeasts evolved a complex regulatory programme to build and maintain their cell wall, the primary structure through which ...
Nada Šupljika   +7 more
wiley   +1 more source

Mechanism of 2'-fucosyllactose degradation by human-associated Akkermansia. [PDF]

open access: yesJ Bacteriol
Padilla L   +7 more
europepmc   +1 more source

Exploring the roles of conserved context‐dependent cis‐regulatory elements (cdCREs) in multicellularity, human health and disease

open access: yesThe FEBS Journal, EarlyView.
Conserved context‐dependent cis‐regulatory elements act as a major reservoir of disease‐associated polymorphisms in the human genome and are also affected by epigenetic change. This ‘state‐of‐the‐art’ review explores the latest developments in studying these enigmatic elements and how the effects of disease‐associated polymorphisms and environmentally ...
Andrew McEwan   +5 more
wiley   +1 more source

The microbiome in endometrial cancer: vaginal milieu matters. [PDF]

open access: yesFront Med (Lausanne)
Govorov I   +11 more
europepmc   +1 more source

In vivo modeling of lethal congenital contracture syndrome 1 suggests pathomechanisms in cellular stress responses

open access: yesThe FEBS Journal, EarlyView.
Gle1 knockout mice fail to segregate cell lineages at the blastocyst stage, resulting in very early embryonic lethality. Gle1 knock‐in (KI) mice harboring a pathogenic variant giving rise to lethal congenital contracture syndrome 1 show both known and novel innervation defects, supportive of multiorgan pathology in human fetuses.
Tomáš Zárybnický   +22 more
wiley   +1 more source

Defining the Enterococcus faecalis Fatty Acid Kinase System of Exogeneous Fatty Acid Utilization

open access: yesMolecular Microbiology, EarlyView.
The enteric bacterium Enterococcus faecalis incorporates fatty acids from the medium and elongates any short chains to lengths suitable for membrane lipids. We have delineated the pathway. ABSTRACT Phospholipid synthesis in Firmicute bacteria differs markedly from that of the paradigm Escherichia coli pathway in that acyl phosphates are a key ...
Huijuan Dong, Qi Zou, John E. Cronan
wiley   +1 more source

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