Results 81 to 90 of about 119 (117)

Senescent Human Liver Endothelial Cells Mediate CD4+ T Cell Recruitment via ICOSL

Immunology, EarlyView.
In this study, we detect senescent endothelial cells within chronically diseased human liver tissues. Next, we develop a novel protocol for the induction of paracrine senescence in primary human liver endothelial cells and explore their functionality.
Daniel A. Patten, Amy Lumley, Alex L. Wilkinson, Ayla O’Keeffe, Kelvin Yin, Niranjan Shirgaonkar, Ran Gao, Ramanuj DasGupta, Matthew Hoare, Shishir Shetty   +9 more
wiley   +1 more source

SlGRF1 mediates gibberellin signaling to control cut‐budding in tomato

Journal of Integrative Plant Biology, EarlyView.
Upon wounding, cytokinin increases to initiate callus formation. Gibberellin enhances this, but later blocks bud formation by suppressing SlGRF1. Wounding‐induced protein SlGRF1 triggers buds via NAM1, EPF4, and ER2. Hormonal shifts control cut‐budding phases.
Yaping Xu, Yinhuan Xie, Huimin Jia, Qianqian Li, Xinqin Liu, Ting Ma, Zhaobo Lang, Qingfeng Niu   +7 more
wiley   +1 more source

FcMAPK4‐phosphorylated FcNOR activates FcERF5 to promote fig fruit softening through activation of FcPG12 expression

Journal of Integrative Plant Biology, EarlyView.
In Ficus carica fruit, the MAP kinase FcMAPK4 phosphorylates the NAC transcription factor FcNOR, which cooperates with ethylene response factor FcERF5 to activate the pectin degradation gene FcPG12, thereby promoting rapid softening of fig fruit. ABSTRACT Rapid softening of fig (Ficus carica L.) fruit during ripening leads to extremely short shelf life;
Yuan Wang, Zhiyi Fan, Yining Wang, Alexander Vainstein, Yuexuan Qiu, Yinan Sun, Huiqin Ma   +6 more
wiley   +1 more source

Arabidopsis inositol polyphosphate kinase activities regulate COP9 deneddylation functions in phosphate homeostasis

Journal of Integrative Plant Biology, EarlyView.
Plant phosphate (Pi) homeostasis relies on coordinated activities of the inositol polyphosphate kinases IPK1 and ITPK1, which balance localized InsP7 biosynthesis to control COP9 signalosome (CSN)‐dependent deneddylation of cullin 1 (CUL1). Perturbation of this equilibrium affects the stability of SPX4, a key negative regulator of phosphate starvation ...
Yashika Walia, Medha Noopur, Ishana Bhattacharya, Bhaskar Chandra Sahoo, Mritunjay Kasera, Naga Jyothi Pullagurla, Smritikana Dutta, Guizhen Liu, Gabriel Schaaf, Henning Jessen, Debabrata Laha, Souvik Bhattacharjee, Saikat Bhattacharjee   +12 more
wiley   +1 more source

Regulation of the Yersinia pseudotuberculosis Type III Secretion System by the CpxAR Two‐Component System

Molecular Microbiology, EarlyView.
Host tissue cues including temperature, oxygen, and iron availability regulate expression of the Yersinia type III secretion system (T3SS) master regulator LcrF. We found that CpxR inhibits LcrF through an indirect, multi‐factorial mechanism and identified the osmolarity‐sensing OmpR/EnvZ system as an additional regulator of LcrF, highlighting ...
Karen Hug, Erin Mettert, Melissa Estrada Escobar, Cristina Vargas Vazquez, David Balderas, Sarvind Tripathi, Laya Ashley, Patricia J. Kiley, Victoria Auerbuch   +8 more
wiley   +1 more source

ERF transcription factor StPti5 is a regulator of endophyte community maintenance in potato

New Phytologist, EarlyView.
Summary We have recently identified an ethylene response factor, StPti5, as a susceptibility factor that negatively regulates immune responses to diverse pathogens. Here, we investigated the role of StPti5 in the processes involved in the colonization of potato with beneficial organisms.
Tjaša Lukan, Karmen Pogačar, Barbara Kraigher, Katja Stare, Teja Grubar Kovačič, Maja Zagorščak, Marko Petek, Polonca Stefanic, Anže Vozelj, Valentina Levak, Tjaša Mahkovec Povalej, Juan M. García, Maria J. Pozo, Eva Álvarez, José M. Franco‐Zorrilla, Maja Križnik, Špela Baebler, Ines Mandić‐Mulec, Kristina Gruden   +18 more
wiley   +1 more source

Natural variation in OsMYB305 downregulating cytokinin‐mediated inhibition of leaf senescence contributes to regional adaptation in rice

New Phytologist, EarlyView.
Proposed regulatory model of OsMYB305 in leaf senescence. Summary Accumulating evidence has identified transcription factors (TFs) as key regulators of the onset and progression of leaf senescence. However, the regulatory role of the rice myeloblastosis (MYB) TF OsMYB305 in this process remains largely unknown.
Boyeong Kim, Jinah Kim, Yejin Shim, Jinku Kang, Hyeryung Yoon, Sung‐Hwan Cho, Nam‐Chon Paek, Kiyoon Kang   +7 more
wiley   +1 more source

Porphyromonas gingivalis GroEL exacerbates orthotopic allograft transplantation vasculopathy via impairment of endothelial cell function

Molecular Oral Microbiology, EarlyView.
Abstract Orthotopic allograft transplantation (OAT) is a significant approach to addressing organ failure. However, persistent immune responses to the allograft affect chronic rejection, which induces OAT vasculopathy (OATV) and organ failure. Porphyromonas gingivalis can infiltrate remote organs via the bloodstream, thereby intensifying the severity ...
Chien‐Sung Tsai, Chun‐Yao Huang, Yi‐Ting Tsai, Chun‐Ming Shih, Ze‐Hao Lai, Chen‐Wei Liu, Yi‐Wen Lin, Feng‐Yen Lin   +7 more
wiley   +1 more source

Spatially Resolved ABA Signalling Reveals Dual Role in Tomato Yield

Plant Biotechnology Journal, EarlyView.
ABSTRACT Abscisic acid (ABA) is a central hormonal regulator of plant adaptation to stress and developmental progression. However, its contribution to agronomic traits such as yield remains unclear due to the pleiotropic nature of ABA signalling. To disentangle distinct physiological functions of ABA, we employed a receptor‐specific gain‐of‐function ...
Fu‐An Wen, Fu‐Dong Mai, Ji‐Bin Xiao, Hong Zhang, Xuan Zhou, Xin‐Yu Yang, Yelena Sterlin, David Karpovsky, Ke‐Ting Li, Juan Wang, Jia Liu, Shi‐Hao Su, Assaf Mosquna, Yu‐Fei Sun   +13 more
wiley   +1 more source

Iterative Genome Engineering Platform Enables Efficient Sucrose Biosynthesis From CO2 in Photosynthetic Synechococcus elongatus UTEX 2973

Plant Biotechnology Journal, EarlyView.
ABSTRACT The single crossover occurring via homologous recombination is a common phenomenon existing among microbes like Escherichia coli, Bacillus subtilis, Vibrio natriegens, Gluconobacter oxydans and most cyanobacteria species, threatening the stability of engineered strains and challenging iterative genetic engineering. Among them, we take the fast‐
Shubin Li, Tao Sun, Dailin Liu, Tong Zhang, Lei Chen, Weiwen Zhang   +5 more
wiley   +1 more source