Results 101 to 110 of about 10,260 (172)

A Concise Synthesis of O-6 and Hydroxylated Analogues of α-Galactosylceramide from D-Lyxose

, 2014
α-Galactosylceramides (α-GalCers)系列化合物因其具重要的免疫調節特，在近幾年來受到關注，並有許多相關合成方法陸續被提出。我們以D-來蘇醣衍生物做為起始物，經九步驟與六步驟得到α-Galactosylceramide O-6衍生物與α-Galactosylceramide 羥基化衍生物，總產率為7%-29%與10%-18%。α-Galactosylceramides are well known as immunostimulating agents having ...
陳吉川, Chen, Ji-Chuan
core  

Probiotic treatment with viable α‐galactosylceramide‐producing Bacteroides fragilis reduces diabetes incidence in female nonobese diabetic mice

Journal of Diabetes
Background We aimed to investigate whether alpha‐galactosylceramide (α‐GalCer)‐producing Bacteroides fragilis could induce natural killer T (NKT) cells in nonobese diabetic (NOD) mice and reduce their diabetes incidence.
Camilla H. F. Hansen, Danica Jozipovic, Line F. Zachariassen, Dennis S. Nielsen, Axel K. Hansen, Karsten Buschard   +5 more
doaj   +1 more source

Activation of human invariant natural killer T cells with a thioglycoside analogue of ?-galactosylceramide

, 2011
Activation of CD1d-restricted invariant NKT (iNKT) cells with the glycolipid ?-galactosylceramide (?-GalCer) confers protection against disease in murine models, however, clinical trials in humans have had limited impact.
O\u27FARRELLY, CLIONA, AMU, SYLVIE, Dunne, Margaret, DOHERTY, DEREK, ZENG, SHIJUAN GRACE, FALLON, PADRAIC, O\u27REILLY, VINCENT   +6 more
core  

Invariant Natural Killer T Cell-Based Immunotherapy Using α-Galactosylceramide-Pulsed CD14⁺ Monocytes for Advanced Gallbladder Cancer. [PDF]

Eur J Case Rep Intern Med
Hanada K, Kobayashi K.
europepmc   +1 more source

<i>In vivo</i> stimulation of natural killer T cells and downstream regulatory T cells to reduce acute graft-versus-host disease. [PDF]

Ann Transl Med
Sluyter R, McErlean G.
europepmc   +1 more source

Glycosphingolipids are essential entry factors for non-influenza orthomyxoviruses. [PDF]

J Gen Virol
Lozano-Montalbá L, Denis Z, Courgnaud V, Moreno-García J, Majzoub K, Sanjuán R, Dufloo J.   +6 more
europepmc   +1 more source

GAL3ST1-Mediated Histone Tyrosine Sulfation Induced by Cancer-Associated Fibroblasts Promotes Gastric Cancer Metastasis. [PDF]

Cancer Res
Lu Y, Wu X, Li B, Yao L, Hou J, Yu B, Li J, Li C, Yan M, Yang Z, Yan C, Zhu Z, Liu B, Tang K, Pan T, Yu Z, Jin Z, Su L.   +17 more
europepmc   +1 more source

Oxygen-responsive bacterial glycosphingolipid links symbiont fitness and immune development in neonatal host. [PDF]

Cell
Heo K, Jung DJ, Yoo JS, Goh B, Kasper DL, Oh SF.   +5 more
europepmc   +1 more source

Preclinical efficacy of combination therapy with allogeneic induced pluripotent stem cell-derived invariant natural killer T and α-galactosylceramide-pulsed antigen-presenting cells. [PDF]

Stem Cell Res Ther
Aoki T, Kobayashi M, Okoshi M, Yamaguchi M, Okura H, Sasaki S, Sasako Y, Kira S, Chang YH, Yakushiji-Kaminatsui N, Sharif J, Matsuda M, Kiuchi M, Hirahara K, Kimura MY, Motohashi S, Koseki H.   +16 more
europepmc   +1 more source

Validating a Human Cell Model of Null Galactosylceramidase (GALC) Enzyme Activity That Recapitulates Krabbe Disease. [PDF]

J Inherit Metab Dis
Starosta RT, Khatoon N, Roberts MS, Le SQ, Austin G, Cui X, Strout G, Schmidt RE, Jiang X, Sands MS, Dickson PI.   +10 more
europepmc   +1 more source