Results 91 to 100 of about 12,328 (239)

The Changing Landscape of Maintenance Therapy in Newly Diagnosed Multiple Myeloma: A Systematic Review With Network Meta‐Analysis of the European Myeloma Network (EMN)

American Journal of Hematology, Volume 101, Issue 9, Page 2353-2370, September 2026.
Our meta‐analysis showed significant improvement of PFS with lenalidomide, proteasome inhibitors, and CD38‐based therapies. A significant OS benefit was noted only with lenalidomide in transplant‐eligible (TE) patients, while CD38‐directed therapy showed a trend toward improved OS.
Heinz Ludwig, Evangelos Terpos, Francesca Gay, Niels W. C. J. van de Donk, Sarah Bernhard, Monika Engelhardt, Gordon Cook, Fredrik Schjesvold, Hermann Einsele, Graham Jackson, Charlotte Pawlyn, María‐Victoria Mateos, Sonja Zweegman, Martin Schreder, Meral Beksaç, Christoph Driessen, Enrique M. Ocio, Rakesh Popat, Leo Rasche, Cyrille Touzeau, Pellegrino Musto, Annemiek Broijl, Meletios Dimopoulos, Roman Hajek, Mario Boccadoro, Pieter Sonneveld   +25 more
wiley   +1 more source

A Randomized Phase II Study of Subcutaneous Mosunetuzumab in Combination With Polatuzumab Vedotin Compared With Rituximab Plus Polatuzumab Vedotin in Patients With Relapsed or Refractory Large B‐Cell Lymphoma

American Journal of Hematology, Volume 101, Issue 9, Page 2177-2189, September 2026.
ABSTRACT Mosunetuzumab plus polatuzumab vedotin has shown promising activity versus rituximab plus polatuzumab vedotin (R‐Pola) in patients with relapsed/refractory (R/R) large B‐cell lymphoma (LBCL; NCT03671018). We present results from the Phase II randomized cohort, evaluating subcutaneous mosunetuzumab plus polatuzumab vedotin (Mosun‐Pola), with ...
Julio C. Chavez, Mariana Bastos‐Oreiro, Catherine Diefenbach, Izidore S. Lossos, Nirav Shah, Sarit Assouline, Adam J. Olszewski, Seema Naik, Nilanjan Ghosh, Song Pham, Michael C. Wei, Connie Batlevi, Iris To, Wahib Ead, Sneha Makadia, Elicia Penuel, Jing Jing, Lihua E. Budde   +17 more
wiley   +1 more source

The Milan Ultrasound Criteria (MUC) in Pediatric Ulcerative Colitis: A Pilot Study of the Correlation With Clinical, Endoscopic and Ultrasound Activity Scores

JCC Plus, Volume 1, Issue 5, September 2026.
ABSTRACT Background Non‐invasive monitoring tools are needed in pediatric ulcerative colitis (UC) to reduce reliance on invasive procedures. The Milan ultrasound criteria (MUC), validated in adults, has not been evaluated in children. Methods In this exploratory pilot study, 16 pediatric UC patients (< 18 years) from two Colombian centers underwent ...
Viviana Parra Izquierdo, Kenneth Ernest‐Suarez, Marjorie Argollo, Juan Sebastián Frías‐Ordoñez, Ginary Orduz, Melquicedec Vargas, Samuel Cubillos, Elisabeth Eggermont, Bram Verstockt   +8 more
wiley   +1 more source

Population Pharmacokinetics and Dose De‐Escalation Regimens of Subcutaneous Vedolizumab in Inflammatory Bowel Disease

JCC Plus, Volume 1, Issue 5, September 2026.
ABSTRACT Background Vedolizumab is a therapeutic antibody approved for the treatment of Crohn's disease and ulcerative colitis. The population pharmacokinetics (popPK) of intravenous (IV) administered vedolizumab have been described, but remain to be defined for subcutaneous (SC) administration.
S. I. Anjie, N. Vreman, K. B. Gecse, M. Löwenberg, G. R. D'Haens, R. A. A. Mathôt   +5 more
wiley   +1 more source

Bronchiectasis as an Underrecognized Extraintestinal Manifestation of Inflammatory Bowel Disease

JCC Plus, Volume 1, Issue 5, September 2026.
ABSTRACT Introduction Inflammatory bowel diseases (IBD) are chronic inflammatory diseases of the gastrointestinal tract, often presenting with extraintestinal manifestations (EIMs). The most prevalent pulmonary EIM is IBD‐associated bronchiectasis (IBD‐BE), which is often overlooked.
Lynn te Slaa, Josje Altenburg, Mark Löwenberg   +2 more
wiley   +1 more source

Optimizing Patient‐Reported Outcome Measurement in an Inflammatory Bowel Disease Care Pathway: Results of the PROMOTION Study

JCC Plus, Volume 1, Issue 5, September 2026.
PROM completion rates in IBD remained largely unchanged after a single patient empowerment intervention, despite a significant short‐term increase immediately after implementation. Sustained and tailored engagement efforts are required to achieve lasting improvements in patient participation and PROM‐based disease monitoring.
Nikki Lembrechts, Stephanie Louis, Karel Van Brantegem, Kurt Geerts, Peter Bossuyt, Lieven Pouillon   +5 more
wiley   +1 more source

Preliminary insights of the genetic diversity and invasion pathways of Cedrela odorata in the Galapagos Islands, Ecuador

Ecology and Evolution
Cedrela odorata is considered the second most invasive tree species of the Galapagos Islands. Although it is listed in CITES Appendix II and there are population losses in mainland Ecuador, in Galapagos it is paradoxically a species of concern due to its
Martina Albuja‐Quintana, Gonzalo Rivas‐Torres, Karla E. Rojas López, Pacarina Asadobay, Walter Palacios Cuenca, Génesis Vinueza, Maria de Lourdes Torres   +6 more
doaj   +1 more source

Patient Experiences and Preliminary Effects of Virtual Reality Based Pain Treatment in Rheumatoid Arthritis Patients With Persistent Pain Despite Low Disease Activity: A Mixed Method Pilot Study

Musculoskeletal Care, Volume 24, Issue 3, September 2026.
ABSTRACT Objective This study aimed to examine the acceptability, usability, patient perceptions and preliminary effects of a virtual reality (VR) based pain management programme for people with rheumatoid arthritis with persistent pain despite low disease activity.
Stijn J. M. Temmink, Marlou A. Bakker, Demy D. Gerritsen, Mirjam C. Hegeman, Liza de Vries, Peter M. ten Klooster, Christina Bode, Harald E. Vonkeman   +7 more
wiley   +1 more source

The Global South's OCBIL Theory Helps Elucidate Evolution, Ecology, and Conservation in Biological and Cultural Diversity

New Zealand Journal of Zoology, Volume 53, Issue 3, September 2026.
Ecological theory has been shaped disproportionately by studies conducted in young, disturbance‐prone, relatively fertile landscapes (YODFELs), mostly in the Global North. Yet, many megadiverse regions in the Global South are dominated by old, climatically buffered, infertile landscapes (OCBILs), resulting in fundamentally different patterns that ...
Stephen D. Hopper, Fernando A. O. Silveira   +1 more
wiley   +1 more source

Undetection of vector-borne viruses in equids of Galapagos Islands

Frontiers in Veterinary Science
Domestic species, including equids, were introduced in the Galapagos Islands in the XIX century. Equine vector-borne diseases are circulating in South America but their occurrence in the Galapagos Island was unknown.
Gina Zanella, Cécile Beck, José-Carlos Valle-Casuso, José-Carlos Valle-Casuso, Madeline Anthony, Madeline Anthony, Marilyn Cruz, Alberto Vélez, Rommel Lenin Vinueza, Gaëlle Gonzalez   +9 more
doaj   +1 more source