Results 81 to 90 of about 50,260 (281)

Increased Risk for Liver Disease in Patients With Chronic Hepatitis B Virus Infection and Low‐Level Viraemia

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
We used an administrative claims dataset to evaluate the relationship between hepatitis B virus (HBV) low‐level viraemia and subsequent liver‐related outcomes in patients with chronic HBV. We found that individuals with HBV low‐level viraemia have an increased risk for liver‐related events (i.e., cirrhosis, decompensation, and hepatocellular carcinoma)
Paul Y. Kwo   +11 more
wiley   +1 more source

One‐Year Effectiveness of Upadacitinib in Perianal Crohn's Disease: A Real‐World GETAID Study

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
In a real‐world cohort of patients with highly refractory perianal Crohn's disease, upadacitinib induced clinical remission at 12 months in 26% of patients with fistulizing disease and 25% of those with isolated anal ulcerations. ABSTRACT Introduction Upadacitinib (UPA) is effective for treating luminal Crohn's disease (CD), but data on perianal CD ...
Nicolas Richard   +13 more
wiley   +1 more source

Urban Land Cover Change in Ecologically Fragile Environments: The Case of the Galapagos Islands

open access: yesLand, 2018
The Galapagos Islands are a unique sanctuary for wildlife and have gone through a fluctuating process of urbanization in the three main inhabited islands. Despite being colonized since the 1800s, it is during the last 25 years that a dramatic increase in
Fátima L. Benítez   +2 more
doaj   +1 more source

An annotated checklist of freshwater copepoda (crustacea, hexanauplia) from continental Ecuador and the Galapagos archipelago [PDF]

open access: yes, 2019
An annotated checklist of the free-living freshwater Copepoda recorded in different regions in Ecuador (including the Amazon, the Andes, the coastal region, and the Galapagos Islands) is here provided.
Corgosinho P. H. C.   +6 more
core   +1 more source

A Care Pathway for the Treatment of IBD Reduces Healthcare Costs and Is Cost‐Effective: Results of the Multicentre IBD Value Study

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
This study provides real‐world evidence that implementing an advanced therapy care pathway for patients with IBD leads to significant healthcare cost savings without compromising quality of life. These findings support broader implementation of care pathways in the management of patients with chronic conditions to optimise care delivery and resource ...
Elyke H. Visser   +12 more
wiley   +1 more source

News from Academy Bay [PDF]

open access: yes, 1983
Planning. A Galapagos marine park. The feral animals on Santiago Island. Can the Hawaiian Petrel be saved? Education and training programmes. Visitors and events at the Charles Darwin Station (May - October 1982)

core  

Novel approaches for drug development against chronic primary pain: A systematic review

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus   +5 more
wiley   +1 more source

A practical, adaptive compliance management framework for improving marine protected area effectiveness

open access: yesConservation Biology, EarlyView.
Abstract Noncompliance regularly undermines the effectiveness of marine protected areas (MPAs) worldwide. The reasons for and drivers of noncompliance depend on the context (e.g., insufficient funding, capacity, neocolonialism, historical conflict), but the prevalent solution offered to curtail noncompliance tends to be more or better enforcement.
B. Bergseth   +10 more
wiley   +1 more source

A review of participatory mapping in conservation science and practice

open access: yesConservation Science and Practice, EarlyView.
There has been a recent increase and diversification in the use of participatory mapping in the field of conservation, however, methodological standards remain both disjointed and confounding. We conducted a comprehensive review of the conservation participatory mapping literature and synthesized geographical, temporal, and topical trends across a ...
Michael B. Kowalski   +3 more
wiley   +1 more source

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