Results 11 to 20 of about 59,850 (232)

Janus kinase 2 inhibition by pacritinib as potential therapeutic target for liver fibrosis

Hepatology, EarlyView., 2022
Diagram of the activation of the profibrotic and procontractile Janus kinase 2 (JAK2)/Ras homolog family member A/Rho‐kinase pathway and the inhibition of phosphorylated JAK2 by pacritinib to inhibit hepatic stellate cell activity. Abstract Background and Aims Janus kinase 2 (JAK2) signaling is increased in human and experimental liver fibrosis with ...
Sandra Torres, Cristina Ortiz, Nadine Bachtler, Wenyi Gu, Leon D. Grünewald, Nico Kraus, Robert Schierwagen, Christoph Hieber, Caroline Meier, Olaf Tyc, Maximilian Joseph Brol, Frank Erhard Uschner, Bart Nijmeijer, Christoph Welsch, Marie‐Luise Berres, Carmen Garcia‐Ruiz, Jose Carlos Fernandez‐Checa, Christian Trautwein, Thomas J. Vogl, Stefan Zeuzem, Jonel Trebicka, Sabine Klein   +21 more
wiley   +1 more source

Modelling the chemical evolution of the Galaxy halo [PDF]

, 2013
We study the chemical evolution and formation of the Galactic halo through the analysis of its stellar metallicity distribution function and some key elemental abundance patterns.
Brusadin, G., Matteucci, F., Romano, D.
core   +2 more sources

He abundances in disc galaxies. I. Predictions from cosmological chemodynamical simulations [PDF]

, 2019
Accepted for publication in A&AWe investigate how the stellar and gas-phase He abundances evolve as a function of time within simulated star-forming disc galaxies with different star formation histories.
Kobayashi, Chiaki, Mackereth, J. Ted, Miglio, Andrea, Montalban, Josefina, Vincenzo, Fiorenzo   +4 more
core   +5 more sources

A 30m Large Program: The CO Line Atlas of the Whirlpool Galaxy Survey (CLAWS) [PDF]

EPJ Web of Conferences, 2022
Robust knowledge of the distribution, amount, and physical/chemical state of the cold molecular (H2) gas is key to understanding galaxy evolution. With the help of multi-CO line observations, it is possible to study the molecular gas distribution and ...
den Brok Jakob, Bigiel Frank
doaj   +1 more source

Chemical evolution of local galaxies

, 2022
We show the results of a study using the spectral synthesis technique study to measure the chemical evolution of local galaxies. The main parameters measured are the chemical enrichment history (ChEH) and the evolution of the stellar mass-metallicity relation (MZR) over cosmic time.
Fariña, Artemi Camps, Blázquez, Patricia Sánchez, Sánchez, Sebastián F.   +2 more
openaire   +1 more source

The Chemical Evolution of the Galaxy [PDF]

Symposium - International Astronomical Union, 1985
Over the last few years, our picture of the chemical evolution of the Galaxy has changed substantially. These changes are of interest because chemical evolution provides a common point of contact for most astrophysical processes of importance to galaxy evolution.
openaire   +1 more source

Effects of thermohaline instability and rotation-induced mixing on the evolution of light elements in the Galaxy : D, 3He and 4He [PDF]

, 2012
Recent studies of low- and intermediate-mass stars show that the evolution of the chemical elements in these stars is very different from that proposed by standard stellar models.
Asplund, Balser, Balser, Balser, Bania, Bennett, Boothroyd, Burles, C. Charbonnel, C. Chiappini, Charbonnel, Charbonnel, Charbonnel, Charbonnel, Charbonnel, Chiappini, Chiappini, Chiappini, Coc, Costa, Cyburt, D. Romano, Dearborn, Denissenkov, Denissenkov, Edmunds, Eggleton, Eggleton, Ekström, Epstein, F. Matteucci, Frogel, Galli, Galli, Geiss, Geiss, Geiss, Gloeckler, Grevesse, Groenewegen, Hirschi, Hirschi, Hogan, Hébrard, Hébrard, Iben, Iwamoto, Jenkins, Kobayashi, Krishnamurti, Lagarde, Larson, Linsky, M. Tosi, Maeder, Marigo, Matteucci, Meynet, N. Lagarde, Oliveira, Palla, Peebles, Pettini, Prantzos, Prodanović, Prodanović, Reeves, Rogers, Romano, Romano, Romano, Rood, Rood, Rood, Rosenblum, Serenelli, Songaila, Sonneborn, Spergel, Steigman, Steigman, Tosi, Traxler, Truran, Ulrich, Vidal-Madjar, Wagoner, Weiss, Zahn   +88 more
core   +3 more sources

On the α/Fe Bimodality of the M31 Disks

The Astrophysical Journal Letters, 2023
An outstanding question is whether the α /Fe bimodality exists in disk galaxies other than in the Milky Way. Here we present a bimodality using our state-of-the-art galactic chemical evolution models that can explain various observations in the Andromeda
Chiaki Kobayashi, Souradeep Bhattacharya, Magda Arnaboldi, Ortwin Gerhard   +3 more
doaj   +1 more source

The building up of the disk galaxy M33 and the evolution of the metallicity gradient

, 2007
The evolution of radial gradients of metallicity in disk galaxies and its relation with the disk formation are not well understood. Theoretical models of galactic chemical evolution make contrasting predictions about the time evolution of metallicity ...
Aller, Arnett, Aubert, Beaulieu, Block, Block, Brooks, Bullock, Chabrier, Chang, Chiappini, Chiappini, Chiappini, Chieffi, Ciardullo, Ciardullo, Corbelli, Corbelli, Crockett, D. Galli, Davidge, de Boer, Devereux, Diaz, E. Corbelli, Elmegreen, Engargiola, Ferrini, Ferrini, Ferrini, Ferrini, Freedman, Freeman, Friel, Gallagher, Galletti, Garnett, Gavilán, Goetz, Henry, Henry, Henry, Herrero, Herwig, Heyer, Hippelein, Hirschi, Holmberg, Hoopes, Hou, Israel, Kennicutt, Kennicutt, Kennicutt, Keres, Kim, Koeppen, Kroupa, Kroupa, Kwitter, L. Magrini, Maciel, Maciel, Maciel, Maciel, Magrini, Magrini, Magrini, Marigo, McCarthy, McConnachie, Mollà, Mollà, Mollà, Monteverde, Monteverde, Naab, Newton, Portinari, Portinari, Regan, Richer, Romano, Rowe, Salpeter, Sandage, Scalo, Scalo, Smith, Stanghellini, Stephens, Talbot, Thielemann, Tiede, Tinsley, Tosi, Urbaneja, Venn, Vílchez, Wakker, Westmeier, Willner, Woosley, Wyse, Young   +104 more
core   +1 more source

Galaxy Formation and Chemical Evolution

International Journal of Astronomy and Astrophysics, 2014
14 pages, 5 ...
openaire   +3 more sources