Results 111 to 120 of about 113,439,941 (280)

EV71 viruses propagated from galectin-1 silenced cells do not carry galectin-1.

, 2015
(A) Galectin-1 is silenced by lentiviral vector-based shRNA. SK-N-SH cells were infected with lentiviruses encoding a galectin-1 shRNA for 48 h. The silencing of galectin-1 in SK-N-SH cells was determined by Western blotting.
Chih-Peng Chang (193745), Yi-Che Tsai (695125), Ai-Li Shiau (695128), Tzong-Shiann Ho (695124), Pei-Huan Lee (695122), Shih-Min Wang (461256), Ya-Fang Wang (439058), Yuh-Ling Chen (695127), Chia-Ming Liu (695123), Chi-Cheng Lin (695126), Chun-Keung Yu (198414), Huan-Yao Lei (193750), Ching-Chuan Liu (461257)   +12 more
core   +1 more source

FOXC1: A Key Transcription Factor of VSMC‐Derived Foam Cell Formation in Atherosclerotic Plaque Instability

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT The instability of atherosclerotic plaques, particularly intraplaque hemorrhage (IPH), drives life‐threatening cardiovascular events, a process in which vascular smooth muscle cell (VSMC)‐derived foam cells play a significant role. We aim to identify key biomarkers associated with VSMC‐derived foam cells and IPH by analyzing data from human ...
Ling‐Lin Qian, Xue‐Ling Li, Li‐Hong Wang, Wei Yang, Yu Jiang   +4 more
wiley   +1 more source

Induction of galectin-1 expression by HTLV-I Tax and its impact on HTLV-I infectivity

Retrovirology, 2008
Background Cell-free Human T-cell Leukemia Virus type I (HTLV-I) virions are poorly infectious and cell-to-cell contact is often required to achieve infection. Other factors might thus importantly contribute in increasing infection by HTLV-I.
Sato Sachiko, Tremblay Michel J, Vargas Amandine, Ouellet Michel, Pelletier Isabelle, Gauthier Sonia, Barbeau Benoit   +6 more
doaj   +1 more source

Mucolipin TRP Cation Channel 1 Depletion Promotes Gastric Cancer Cell Ferroptosis Through the AKT Pathway

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Mucolipin TRP cation channel 1 (MCOLN1), also called TRPML1, drives the progression of various cancers and inhibits ferroptosis in a number of diseases. This study aimed to investigate whether MCOLN1 depletion regulates ferroptosis in gastric cancer and its molecular regulatory crosstalk with the AKT pathway.
Jing Wang, Jun‐Chen Ge, Jian Ma, Xin Wang, Wen Jia, Li Zhu   +5 more
wiley   +1 more source

Therapeutic Targeting of the Galectin-1/miR-22-3p Axis Regulates Cell Cycle and EMT Depending on the Molecular Subtype of Breast Cancer

Cells
Breast cancer is a highly heterogeneous disease; hence, it is crucial to understand its biology and identify new targets for the development of effective treatments. Galectin-1 is known to play an oncogenic role in breast cancer progression.
Ju Yeon Kim, Jun Ho Lee, Eun Jung Jung, Young Sim Son, Hee Jin Park, Jae Myung Kim, Taejin Park, Sang-Ho Jeong, Jinkwon Lee, Tae Han Kim, Seon Min Lee, Jeong Doo Heo   +11 more
doaj   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Effect of galectin‐1 on prognosis and responsiveness of immune checkpoint plus tyrosine kinase inhibition in renal cell carcinoma

Cancer Medicine
Background In renal cell carcinoma (RCC), no clinically available biomarker has been utilized for checkpoint inhibitor immunotherapy (IO) + tyrosine kinase inhibitor (TKI) combinations.
Jiajun Wang, Sihong Zhang, Ying Wang, Yanjun Zhu, Xianglai Xu, Jianming Guo   +5 more
doaj   +1 more source

Mass Spectrometry Insights Into Post‐Translational Modifications in Extracellular Vesicles

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐enclosed structures secreted by virtually all living cells, serving as essential mediators of intercellular communication in both physiological and pathological processes. There is growing interest in their potential applications as biomarkers, therapeutic targets, and drug delivery systems, which ...
Dávid Virág, Krisztián Márk Karvaly, Alexandra Molnár, Mirjam Balbisi, Júlia Németh, Lilla Turiák   +5 more
wiley   +1 more source

Cardiorespiratory fitness and the association with galectin-1 in middle-aged individuals.

PLoS ONE
Galectin-1 plays a functional role in human metabolism and the levels are altered in obesity and type 2 diabetes (T2D). This study investigates the association of cardiorespiratory fitness (CRF) with galectin-1 and the interconnection with body fatness ...
Daniel Arvidsson, Vagner Ramon Rodrigues Silva, Örjan Ekblom, Elin Ekblom-Bak, Emanuel Fryk, Per-Anders Jansson, Mats Börjesson   +6 more
doaj   +1 more source

Electrical Modalities in the Rehabilitation of Peripheral Nerve Injuries: State of the Literature and Current Clinical Applications

Muscle &Nerve, EarlyView.
ABSTRACT Peripheral nerve injuries (PNIs) are a common cause of long‐term motor and sensory disability despite advances in microsurgical repair. Functional recovery following PNI depends not only on axonal regeneration, but also on preservation of distal nerve pathways, maintenance of neuromuscular junction integrity, prevention of irreversible muscle ...
Sarah M. Smith, Kirsten M. Schlosser, Ranee Munaim, Stephanie H. Vu, JulieAnn H. Uh, Yusha K. Liu   +5 more
wiley   +1 more source