Results 121 to 130 of about 21,276,578 (296)

Glycosylation pattern of brush border-associated glycoproteins in enterocyte-like cells: involvement of complex-type N-glycans in apical trafficking [PDF]

open access: yes, 2009
We have previously reported that galectin-4, a tandem repeat-type galectin, regulates the raft-dependent delivery of glycoproteins to the apical brush border membrane of enterocyte-like HT-29 cells.
Huet, Guillemette   +8 more
core   +1 more source

Unveiling the roles of extracellular vesicles in hematologic malignancies: Pathogenesis, diagnostic tools, and clinical translation

open access: yesInterdisciplinary Medicine, EarlyView.
Extracellular vesicles play pivotal roles in both healthy hematopoiesis and hematologic malignancies. They not only regulate hematopoietic stem cell fitness but also drive cancer progression and drug resistance. Their clinical potential spans from serving as non‐invasive biomarkers to acting as innovative therapeutic platforms and drug delivery ...
Fengyu Chen   +5 more
wiley   +1 more source

Galectin-1 is expressed in early-type neural progenitor cells and down-regulates neurogenesis in the adult hippocampus

open access: yesMolecular Brain, 2011
Background In the adult mammalian brain, neural stem cells (NSCs) proliferate in the dentate gyrus (DG) of the hippocampus and generate new neurons throughout life.
Imaizumi Yoichi   +6 more
doaj   +1 more source

Serum Apelin‐13 and Galectin‐3 in COVID‐19: Associations With Routine Biochemical Parameters and Diagnostic Performance in a Case–Control Study

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Serum Apelin‐13 and Galectin‐3 levels were measured by ELISA in COVID‐19–positive patients and controls and evaluated alongside routine biochemical parameters. COVID‐19 patients showed significant alterations in liver, renal, inflammatory, and metabolic markers.
İsmail Uğurlu
wiley   +1 more source

Galectin-3 Gene (Lgals3) +292c Allele Is a Genetic Predisposition Factor for Rheumatoid Arthritis in Taiwan

open access: yes, 2012
Galectin-3 is a beta-galactoside-binding lectin which is involved in modulating inflammation and apoptosis. Elevated expression of galectin-3 has been demonstrated in synovium of rheumatoid arthritis (RA).
HU, CHUNG-YI;CHANG, SHENG-KAI;WU, CHIEN-SHENG;TSAI, WEI-I;HSU, PING-NING   +1 more
core   +1 more source

SPROUTS_DB: An Implemented Database of Contaminants for Extracellular Vesicle Proteomics Studies

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Current proteomics techniques allow rapid identification and quantification of proteins within any given biological source. However, LC–MS/MS proteomics is vulnerable to laboratory and sample‐associated contaminants. Therefore, accurate identification and annotation of such contaminants is crucial for development of reliable databases ...
Maria Gaetana Giovanna Pittalà   +10 more
wiley   +1 more source

EV71 viruses propagated from galectin-1 silenced cells do not carry galectin-1.

open access: yes, 2015
(A) Galectin-1 is silenced by lentiviral vector-based shRNA. SK-N-SH cells were infected with lentiviruses encoding a galectin-1 shRNA for 48 h. The silencing of galectin-1 in SK-N-SH cells was determined by Western blotting.
Chih-Peng Chang (193745)   +12 more
core   +1 more source

From cytokine storm to renal scarring in diabetic kidney disease: Biomarkers, risk stratification, and precision therapeutics

open access: yesPrecision Medical Sciences, EarlyView.
Hyperglycemia‐driven cytokine activation initiates a sustained inflammatory cascade in diabetic kidney disease, promoting cellular injury and fibrogenic signaling. Integrating cytokine‐based biomarkers with risk stratification enables precision therapeutics that target inflammation and fibrosis, ultimately aiming to halt progression from early renal ...
Emmanuel Ifeanyi Obeagu
wiley   +1 more source

CD38 regulates chronic lymphocytic leukemia proliferation via CD45 phosphatase activity

open access: yesMolecular Therapy: Oncology
Chronic lymphocytic leukemia (CLL) growth is dependent on both B cell receptor (BCR) signaling and signals from microenvironmental T helper (Th) cells.
John F. Imbery   +11 more
doaj   +1 more source

Recent Advances in Photocatalyst‐Driven Protein Labeling and Proximity Mapping

open access: yesThe Chemical Record, EarlyView.
Photocatalyst‐driven protein labeling and proximity mapping have rapidly advanced as powerful strategies for spatiotemporal control in complex biological environments. This review integrates recent developments across single‐electron transfer and energy transfer‐based mechanisms and highlights how catalyst design, reactive intermediates, and diffusion ...
Shinichi Sato   +3 more
wiley   +1 more source

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