Results 181 to 190 of about 29,735,201 (297)

Gastric cancer-secreted galectin-1 promotes peritoneal mesothelial-mesenchymal transition to prime peritoneal metastasis soil. [PDF]

iScience
Huang C, Jiang Z, Shen X, Ding Q, Wang H, Cheng Z, Liu G, Zhao X, You X.   +8 more
europepmc   +1 more source

Single‐Cell Reveal GALNT7‐Dependent Ferroptosis Suppression as a Mechanism of Immunotherapy Resistance in Non‐Small Cell Lung Cancer

Advanced Science, Volume 13, Issue 50, 7 September 2026.
Integrated clinical and mechanistic analyses identify GALNT7 as a ferroptosis‐suppressive regulator associated with immunotherapy resistance in non‐small cell lung cancer. GALNT7 depletion promotes lipid peroxidation, mitochondrial dysfunction, and ferroptosis, enhances CD8+ T‐cell activation and IFN‐γ production, and sensitizes tumors to PD‐1 blockade,
Jiadi Gan, Qian Zheng, Deng Liu, Ruichao Nie, Menglin Yao, Xiaolong Tang, Renjie Xu, Jinghong Xian, Wenjun Meng, Wenxin Luo, Dan Liu, Guiyi Ji   +11 more
wiley   +1 more source

Human multi-tissue transcriptomics identifies galectin-1 and follistatin-like 1 as exerkines with distinct transcript-to-serum coupling after exercise. [PDF]

J Physiol
Song J, Cho ES, Kwon YR, Park JS, Nam JS, Kim Y.   +5 more
europepmc   +1 more source

Galectin-1 Inhibitor OTX008 [PDF]

, 2020
openaire   +1 more source

Targeting the HSPA8‐CMA‐ATP6V1A Axis Triggers Lysosomal Hyperacidification and Catastrophic Vacuolation in Prostate Cancer

Advanced Science, Volume 13, Issue 51, 14 September 2026.
Our experimental evidence supports a model in which ALO targets the HSPA8‐CMA‐ATP6V1A axis to induce lysosomal hyperacidification and initiate osmotic and lipidomic stress. These changes are associated with LMP and loss of lysosomal integrity in prostate cancer cells.
Bingzheng An, Ze Gao, Shuo Chen, Liwei Meng, Chen Zhang, Kefan Song, Haochen Cui, Lei Yan, Zhiqing Fang   +8 more
wiley   +1 more source

Expression and significance of PIBF combined with Galectin-1 in cervical precancerous lesions. [PDF]

Front Med (Lausanne)
Wang H.
europepmc   +1 more source

Engineering Antibodies into Targeted Chimeras: From Recognition Modules to Programmable Degraders

Advanced Science, Volume 13, Issue 50, 7 September 2026.
Antibody can be engineered into diverse lysosome‐targeting chimeras that convert target recognition into active degradation. By coupling antibody binding with recruited receptors, encoded domains, conjugated ligands, or nanoparticle scaffolds, these antibody‐associated targeted chimeras (AbTACs) platforms direct extracellular and membrane proteins ...
Kaige Chen, Quanyin Hu
wiley   +1 more source

A Zebrafish Galectin-1 Isoform Is Expressed in Skin and Gills and Binds to Bacteria, Bacterial Adhesin Receptors, and Epidermal Mucus Glycans. [PDF]

Int J Mol Sci
Feng C, Abernathy K, Wang S, Zong G, Zmora N, Shupp A, Iqbal M, Wang LX, Vasta GR.   +8 more
europepmc   +1 more source

Moringa oleifera Lam. Seed Lectin (WSMoL) Attenuates Parkinsonian Symptoms in Mice via Anti‐Inflammatory, Antioxidant, and Neurotransmitter‐Modulating Effects

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
WSMoL attenuates motor impairment, neuroinflammation, oxidative stress, and monoamine depletion in a rotenone‐induced model of Parkinson's disease. The involvement of D1 receptor‐mediated signaling is demonstrated, providing new insights into the mechanisms underlying its neuroprotective effects and supporting WSMoL as a promising candidate for further
Leydianne Leite de Siqueira Patriota, Emanuel Davi Lima de Matos Leão, Maria Nívea Bezerra da Silva, Amanda de Oliveira Marinho, Bárbara Raíssa Ferreira de Lima, Jainaldo Alves da Costa, Luciclaudio Cassimiro de Amorim, Valéria Bianca de Souza Santos, Patrícia Maria Guedes Paiva, Michelly Cristiny Pereira, Daniella Carla Napoleão, Jorge Vinícius Fernandes Lima Cavalcanti, Leucio Duarte Vieira, Michelle Melgarejo da Rosa, Thiago Henrique Napoleão   +14 more
wiley   +1 more source

Design of galectin-1-conjugated nanoparticles as potential immunomodulatory agents. [PDF]

RSC Med Chem
Ghosh C, Yao L, Sigler M, Di Lella S, Cagnoni AJ, Rabinovich GA, Seeberger PH.   +6 more
europepmc   +1 more source