Results 201 to 210 of about 21,276,578 (296)

A Dynamic Change of Microglial States Occurs During the Transition From Photoreceptor Degeneration to Regeneration in Zebrafish pde6c Mutants

Glia, Volume 74, Issue 6, June 2026.
Zebrafish pde6c mutants undergo photoreceptor degeneration from 5 dpf, but rods regenerate from 4 wpf. scRNA‐seq of retinal microglia reveals dynamic change of states between 5 dpf and 4 wpf. Two states emerge specifically during regeneration. ABSTRACT Microglia, brain‐resident immune cells, maintain brain homeostasis.
Darshini Ravishankar, Yuki Takeuchi, Ichiro Masai   +2 more
wiley   +1 more source

Serum Galectin-1 as a Diagnostic Biomarker in Endometriosis: A Prospective Longitudinal Study. [PDF]

Int J Mol Sci
Brubel R, Balogh DB, Polgar B, Szereday L, Hudelist G, Acs N, Bokor A.   +6 more
europepmc   +1 more source

Galectin-1 levels do not predict outcomes in undifferentiated arthritis: a two-year prospective observational study. [PDF]

Front Immunol
Valero-Martínez C, Pardines-Ortiz M, Montes N, Ortiz AM, García-Vicuña R, González-Alvaro I, Triguero-Martínez A.   +6 more
europepmc   +1 more source

Mapping the Global Clinical Landscape of Pharmacological Therapies for Heart Failure With Preserved Ejection Fraction: An Analysis Based on ClinicalTrials.gov (2003–2025)

iMetaMed, Volume 2, Issue 2, June 2026.
This study analyzed 236 heart failure with preserved ejection fraction (HFpEF) pharmacological trials registered on ClinicalTrials.gov from 2003 to 2025, revealing a post‐2016 surge (76.3%), U.S. dominance (58.5%), and prominence of SGLT2 inhibitors/novel therapies (each 13.1%).
Yucheng Hou, Jingwei Zhao, Yuqian Tang, Tan Liu, Zhiao Zhang, Ziheng Wang, Han Shen   +6 more
wiley   +1 more source

Tumor-Intrinsic PD-L1 Promotes Breast Cancer Proliferation Through Livin and Galectin-1-Mediated Regulation of SKP2 Expression. [PDF]

Int J Mol Sci
Elfoly M, Alaiya A, Al-Hazzani AA, Al-Alwan M, Ghebeh H.   +4 more
europepmc   +1 more source

Impact of Isolation Techniques on the Content of Small Extracellular Vesicles

Journal of Extracellular Vesicles, Volume 15, Issue 6, June 2026.
ABSTRACT An important topic of discussion amongst the extracellular vesicle (EV) research field is which genetic materials are considered true constituents of EV cargo. What were once regarded as non‐EV components have now evolved to be potentially essential to EV composition, serving as key mediators in communication.
Yue Su, Kekoolani S. Visan, Sarah Voss, Marta Prieto‐Vila, Juntaro Matsuzaki, Jason Ying Kuen Chan, Judy Wai Ping Yam, Andreas Möller   +7 more
wiley   +1 more source

Galectin-1, Adiponectin, Leptin, and the Adiponectin to Leptin Ratio as Predictors of Metabolic Syndrome: Influence of Age and Body Mass Index. [PDF]

Biomed Res Int
Abdulateef DS, Mahmood TA, Arkawazi LI.
europepmc   +1 more source

miR-22-Galectin-1 as an integral signaling axis in regulating metabolism and immunity in HCC. [PDF]

Biomark Res
Hu Y, Setayesh T, Jena PK, Ji Y, Testerman T, Liu R, Shih TC, Wang XJ, Liu FT, Lam KS, Wan YY.   +10 more
europepmc   +1 more source

Inhibition of PLA2G15 Alleviates Palmitic Acid‐Induced Lysosomal Membrane Permeabilization in Human Nucleus Pulposus Cells During Intervertebral Disc Degeneration

JOR SPINE, Volume 9, Issue 2, June 2026.
LMP is responsible for lysosomal dysfunction in IDD. The lipid composition changes in the lysosomal membrane, mediated by PLA2G15, are the cause of LMP. The C/EBPα significantly promotes PLA2G15 expression under PA overload stress. Inhibition of PLA2G15 alleviates PA‐induced LMP by inhibiting the hydrolysis of lysosomal membrane phospholipids. ABSTRACT
Liqun Duan, Jiang Jiang, Shuangshuang Tu, Chuanfu Li, Yijun Dong, Yongjin Li, Wenzhi Zhang, Xi Chen   +7 more
wiley   +1 more source

Selective Nanobody-Derived Minibodies Targeting Galectin-1 and -7 Reveal Non-Redundant Glyco-Immune Functions and Therapeutic Potential in Triple-Negative Breast Cancer. [PDF]

J Med Chem
Nehmé R, Fortier M, Granger Joly de Boissel P, Caza F, Fronton F, Bourguignon L, Charpentier T, Fuselier C, Ferchiou S, D'Auteuil N, Gaboury L, Lamarre A, Chatenet D, St-Pierre Y.   +13 more
europepmc   +1 more source