scRNA‐Seq in Gastric Cancer Reveals Macrophage‐Derived C1q as a Diagnostic Marker
Single‐cell sequencing of GC analyzed the tumor microenvironment and discovered the C1QA+ TAMs subpopulation with immunosuppressive function. The role of C1q in the prognosis and diagnosis of GC was demonstrated through plasma and tumor tissue from the GC cohort.
Saisai Gong +6 more
wiley +1 more source
Galectin-1, Adiponectin, Leptin, and the Adiponectin to Leptin Ratio as Predictors of Metabolic Syndrome: Influence of Age and Body Mass Index. [PDF]
Abdulateef DS, Mahmood TA, Arkawazi LI.
europepmc +1 more source
Interleukin‐12: Central Roles in Immune Regulation and Disease Therapy
IL‐12 levels are tightly regulated to balance effective protective immunity against infections and cancer with the risk of excessive inflammation and autoimmune disease. Both insufficient and excessive IL‐12 activity can therefore be detrimental, highlighting the importance of precisely controlling its production and signaling. ABSTRACT Interleukin‐12 (
Anthi Psoma, Geert van den Bogaart
wiley +1 more source
miR-22-Galectin-1 as an integral signaling axis in regulating metabolism and immunity in HCC. [PDF]
Hu Y +10 more
europepmc +1 more source
Encoding Cell‐Surface Receptor Function Through Glycosylation: Lessons From CD44
CD44 function is not solely determined by its protein sequence, it is dynamically encoded by its glycosylation state. Glycan remodeling generates distinct functional receptor states that regulate ligand recognition, receptor organization, lectin interactions, and signaling.
María Payá‐García +7 more
wiley +1 more source
Selective Nanobody-Derived Minibodies Targeting Galectin-1 and -7 Reveal Non-Redundant Glyco-Immune Functions and Therapeutic Potential in Triple-Negative Breast Cancer. [PDF]
Nehmé R +13 more
europepmc +1 more source
Disorder of the immune and inflammatory response involving galectin-1, -3 and -7 in women with invasive breast cancer - potential importance in diagnosis and monitoring the course of the disease. [PDF]
Królewska-Daszczyńska P +5 more
europepmc +1 more source
Differential Expression of Galectin-1 and Galectin-9 in Immune-Mediated Inflammatory Diseases. [PDF]
Valero-Martínez C +14 more
europepmc +1 more source

