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A pivotal role for galectin-1 in fetomaternal tolerance

Nature Medicine, 2007
A successful pregnancy requires synchronized adaptation of maternal immune-endocrine mechanisms to the fetus. Here we show that galectin-1 (Gal-1), an immunoregulatory glycan-binding protein, has a pivotal role in conferring fetomaternal tolerance.
Blois, Sandra M   +16 more
openaire   +2 more sources

Galectin-1 in injury and regeneration

2009
In higher vertebrates, injury to both sensory and motor axons within the central nervous system (CNS) results in permanent loss of sensation and paralysis. In contrast, peripheral nervous system (PNS) injuries are often followed by functional recovery.
openaire   +1 more source

Galectin-1: Forms and Functions

2012
Galectin-1 (Gal-1) is an animal lectin ranging from Caenorhabditis elegans to humans, which is defined by the affinity for β-galactosides and by significant sequence similarity in carbohydrate-binding site. Gal-1 is differentially expressed by various normal and pathological tissues and appears to be functionally polyvalent, with a wide range of ...
openaire   +1 more source

An updated patent review of galectin-1 and galectin-3 inhibitors and their potential therapeutic applications (2016–present)

Expert Opinion on Therapeutic Patents, 2021
Swetha Sanam   +2 more
exaly  

Galectin-1

1998
Tak W. Mak   +4 more
openaire   +1 more source

Emerging roles of Galectin-3 in diabetes and diabetes complications: A snapshot

Reviews in Endocrine and Metabolic Disorders, 2022
Chunlan Zhang, Tian Li, Yang Xiao
exaly  

Galectin-1 (LGALS1)

Science-Business eXchange, 2014
openaire   +1 more source

Galectin-3: One Molecule for an Alphabet of Diseases, from A to Z

International Journal of Molecular Sciences, 2018
Alberto Ricci   +2 more
exaly  

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