Results 251 to 260 of about 113,439,941 (280)

Tissue fibronectin is an endogenous ligand for galectin-1

Glycobiology, 1995
A 14K beta-galactoside-binding lectin (galectin-1) is present in many animal tissues. In a search for endogenous ligands, we surveyed galectin-1-binding proteins in human placenta. Extract of human placenta with 2 M urea was applied to a Sepharose 4B column conjugated with galectin-1 purified from frog (Rana catesbeiana) eggs. Two major proteins eluted
Y, Ozeki, T, Matsui, Y, Yamamoto, M, Funahashi, J, Hamako, K, Titani   +5 more
openaire   +2 more sources

Expression and Functions of Galectin-1 in Sensory and Motoneurons

Current Drug Targets, 2005
Galectin-1 (Gal1) was the first identified member of the galectin family of beta-galactosidase-binding proteins. Gal1 has important roles in processes fundamental to growth and survival of an organism, including cell adhesion, cell proliferation and apoptosis, and is expressed in many tissues, including the nervous system.
A D, Gaudet, J D, Steeves, W, Tetzlaff, M S, Ramer   +3 more
openaire   +2 more sources

Galectin‐1 studies in proliferative diabetic retinopathy

Acta Ophthalmologica, 2019
AbstractPurposeGalectin‐1 regulates endothelial cell function and promotes angiogenesis. We investigated the hypothesis that galectin‐1 may be involved in the pathogenesis of proliferative diabetic retinopathy (PDR).MethodsVitreous samples from 36 PDR and 20 nondiabetic patients, epiretinal fibrovascular membranes from 13 patients with PDR, rat retinas
Ahmed M. Abu El‐Asrar, Ajmal Ahmad, Eef Allegaert, Mohammad Mairaj Siddiquei, Kaiser Alam, Priscilla W. Gikandi, Gert De Hertogh, Ghislain Opdenakker   +7 more
openaire   +2 more sources

Galectin-1: Forms and Functions

2012
Galectin-1 (Gal-1) is an animal lectin ranging from Caenorhabditis elegans to humans, which is defined by the affinity for β-galactosides and by significant sequence similarity in carbohydrate-binding site. Gal-1 is differentially expressed by various normal and pathological tissues and appears to be functionally polyvalent, with a wide range of ...
openaire   +1 more source

Galectin-1 in injury and regeneration

2009
In higher vertebrates, injury to both sensory and motor axons within the central nervous system (CNS) results in permanent loss of sensation and paralysis. In contrast, peripheral nervous system (PNS) injuries are often followed by functional recovery.
openaire   +1 more source

Galectin-1

1998
Tak W. Mak, Josef Penninger, John Roder, Janet Rossant, Mary Saunders   +4 more
openaire   +1 more source

Emerging Roles of Galectin-3 in Diabetes and Diabetes Complications: A Snapshot

Reviews in Endocrine and Metabolic Disorders, 2022
Chunlan Zhang, Tian Li, Yang Xiao
exaly  

Bend It Like Galectin 3

Nature Reviews Molecular Cell Biology, 2014
Andrea du Toit
exaly  

Galectin-1 (LGALS1)

Science-Business eXchange, 2014
openaire   +1 more source

Galectin-3 Is an Important Mediator of VEGF- and bFGF-Mediated Angiogenic Response

Journal of Experimental Medicine, 2010
Fu-Tong Liu
exaly