Results 241 to 250 of about 29,735,201 (297)

Prognostic Influence of Galectin-1 in Gastric Adenocarcinoma. [PDF]

Biomedicines
Díaz Del Arco C, Estrada Muñoz L, Cerón Nieto MLÁ, Molina Roldán E, Fernández Aceñero MJ, García Gómez de Las Heras S.   +5 more
europepmc   +1 more source

Functional Specialization of Clathrin‐Independent Endocytic Routes: Mechanisms and Cellular Roles

Traffic, Volume 27, Issue 3, September 2026.
Distinct clathrin‐independent endocytic (CIE) routes support specialized cellular functions across different contexts. Created with Biorender.com. ABSTRACT Clathrin‐independent endocytosis (CIE) comprises a diverse repertoire of internalization mechanisms that operate in parallel with clathrin‐mediated endocytosis.
Andrea Francesco Benvenuto, Amir Fardin, Matteo Balestra, Pier Paolo Di Fiore, Chiara Tordonato, Sara Sigismund   +5 more
wiley   +1 more source

Nuclear Galectin-1 promotes <i>KRAS</i>-dependent activation of pancreatic cancer stellate cells. [PDF]

Proc Natl Acad Sci U S A
Vinaixa J, Martínez-Bosch N, Gibert J, Manero-Rupérez N, Santofimia-Castaño P, Baudou FG, Vera RE, Pease DR, Iglesias M, Sen S, Wang X, Almada LL, Marks DL, Moreno M, Iovanna JL, Rabinovich GA, Fernandez-Zapico ME, Navarro P.   +17 more
europepmc   +1 more source

Structural and Biophysical Characterization of C‐Glycosylic 1,2‐Thiodisaccharides Reveals Determinants of Selective Binding to Galectin‐7 and Galectin‐8N

ChemMedChem, Volume 21, Issue 16, 27 August 2026.
The molecular basis of galectin recognition by C‐glycosylic 1,2‐thiodisaccharides is revealed. While Gly‐1 provides a conserved affinity driving interaction, Gly‐2 governs isoform selectivity through contacts with variable CRD regions. Unique galectin‐8N residues are identified as attractive handles for the development of next‐generation selective ...
Anastasia S. Tsagkarakou, Anastassia L. Kantsadi, Vasiliki I. Theodoridou, Nikolaos Veliotis, László Lázár, János József, László Juhász, George Kontopidis, Hakon Leffler, Ulf J. Nilsson, László Somsák, Demetres D. Leonidas   +11 more
wiley   +1 more source

Stromal-Like Cells and Retinal Pigment Epithelium Modulate Choroidal Sprouting Through Galectin-1-Dependent and Independent Pathways. [PDF]

FASEB J
Ridano ME, Hanke-Gogokhia C, Lehmann GL, Caceres PS, Vaglienti MV, Ceschin D, Schreiner R, Croci DO, Torroja-Fungairiño C, Rodriguez-Boulan E, Benedicto I, Rabinovich GA, Sánchez MC.   +12 more
europepmc   +1 more source

A proinflammatory stem cell niche drives myelofibrosis through a targetable galectin-1 axis. [PDF]

Sci Transl Med
Li R, Colombo M, Wang G, Rodriguez-Romera A, Benlabiod C, Jooss NJ, O'Sullivan J, Brierley CK, Clark SA, Pérez Sáez JM, Fernández PA, Schoof EM, Porse B, Meng Y, Khan AO, Wen S, Dong P, Zhou W, Sousos N, Murphy L, Clarke M, Olijnik AA, Wong ZC, Karali CS, Sirinukunwattana K, Ryou H, Norfo R, Cheng Q, Carrelha J, Ren Z, Thongjuea S, Rathinam VA, Krishnan A, Royston D, Rabinovich GA, Mead AJ, Psaila B.   +36 more
europepmc   +1 more source

Multi-omics analysis identified LGALS1 (Galectin-1) as a novel therapeutic target for clear cell renal cell carcinoma via targeting epithelial or endothelial cells. [PDF]

Discov Oncol
Tan X, Chen Y, Jiang C, Shao J, Wang X.
europepmc   +1 more source

Galectin-1 Induces the Production of Immune-Suppressive Cytokines in Human and Mouse T Cells. [PDF]

Int J Mol Sci
Herman KD, Holyer I, Humphries DC, Adamska A, Roper JA, Peterson K, Zetterberg FR, Pedersen A, MacKinnon AC, Slack RJ.   +9 more
europepmc   +1 more source

Galectin-1-Induced Tumor Associated Macrophages Repress Antitumor Immunity in Hepatocellular Carcinoma Through Recruitment of Tregs. [PDF]

Adv Sci (Weinh)
Yu X, Qian J, Ding L, Pan C, Liu X, Wu Q, Wang S, Liu J, Shang M, Su R, Guo D, Xie H, Yin S, Zhou L, Zheng S.   +14 more
europepmc   +1 more source