MedComm, Volume 7, Issue 9, September 2026.The clinical manifestations of PFO. Although the majority of PFOs are benign and asymptomatic, they can present with a variety of clinical manifestations, or coexisting with other diseases and aggravating their symptoms, including cerebral diseases (such as CS, epilepsy, TIA, or migraine), systemic embolism (such as embolism in renal artery, coronary ...
Linlin Meng +6 more
wiley +1 more source
Galectin-3 in the Lateral Ventricle Regulates Immune Functions. [PDF]
ASN NeuroSoares LC, Bernhardova H, Szele FG.
europepmc +1 more source
High‐Content CRISPR Screening: Methods and Applications
MedComm, Volume 7, Issue 9, September 2026.High‐content CRISPR screening represents a paradigm shift in functional genomics, moving beyond traditional survival‐based readouts to enable multidimensional mapping of genotype–phenotype relationships. This review systematically outlines the methodological evolution of this approach, detailing advances in perturbation modalities, delivery systems ...
Yike Zhang +6 more
wiley +1 more source
Galectin 3 expression in gastrointestinal tumors identified through comprehensive bioinformatic mapping. [PDF]
Discov OncolChiriva-Internati M +4 more
europepmc +1 more source
Tissue‐Resident Macrophage in Inflammation and Cancer
MedComm, Volume 7, Issue 9, September 2026.Opposing macrophage functions in inflammation and cancer converge on shared mechanistic nodes, informing cross‐disease therapeutic strategies. ABSTRACT Tissue‐resident macrophages (TRMs) are long‐lived immune cells strategically distributed across organs, where their functional plasticity enables both homeostatic maintenance and pathological ...
Siyuan Huang +13 more
wiley +1 more source
Predictive Value of Serum Pentraxin 3 and Galectin-3 in Early Pregnancy for Gestational Diabetes Mellitus in Chinese Women. [PDF]
Int J Womens HealthSu Q, Yang J, Yang J, Zhang H, Fan Y.
europepmc +1 more source
Cancer Neuroscience: From Local Neuro–Immune Microenvironments to Systemic Brain–Body Circuitry
MedComm, Volume 7, Issue 9, September 2026.This review outlines the cancer neuroscience paradigm, spanning systemic brain–body circuitry and local neuro–immune–tumor microenvironments. We discuss how tumors promote axonogenesis and pseudo‐synapse formation, and how sensory neuropeptides, such as CGRP, contribute to CD8+ T‐cell exhaustion.
Mingxuan Xie +7 more
wiley +1 more source
Proteomic Remodeling in the Failing Left Ventricle Adapting to Dyssynchrony
PROTEOMICS – Clinical Applications, Volume 20, Issue 5, September 2026.ABSTRACT Purpose In heart failure, dyssynchrony is associated with accelerated cardiac remodeling and a worse prognosis. Both restored with resynchronization. We have previously developed a mouse model of dyssynchrony and resynchronization and here assess changes in protein expression within that model.
Karin Ljung +4 more
wiley +1 more source
Serum Galectin-3 Levels Correlate with Reduced Vascular Reactivity in Patients with Coronary Artery Disease. [PDF]
Medicina (Kaunas)Huang PY +4 more
europepmc +1 more source
Molecular Mechanisms of Age‐Related Taste Dysfunction Deciphered by Spatiotemporal Transcriptomics
Aging Cell, Volume 25, Issue 9, September 2026.Multi‐omics profiling reveals that aging impairs stem/progenitor cell differentiation and taste bud regeneration in the posterior tongue. Age‐related macrophage polarization remodeling, marked by the accumulation of pro‐inflammatory M1 macrophages, contributes to a Thbs1‐enriched inhibitory niche that limits taste cell growth and differentiation ...
Wandong Zhao +15 more
wiley +1 more source