A proteomic investigation of forebrain regeneration in the leopard gecko (Eublepharis macularius)
Our investigation reveals ontogenetic, injury‐ and regeneration‐associated proteomic changes in the leopard gecko forebrain. Abstract Background The ability to replace lost or damaged neurons following an injury is termed reactive neurogenesis. Although reactive neurogenesis has been reported in several lizard species, the molecular mechanisms ...
Alexandra I. Noble +2 more
wiley +1 more source
Methodological considerations in interpreting serum galectin‐3 as a predictor of incident type 2 diabetes [PDF]
Journal of Diabetes Investigation, EarlyView.
Chen L, Weng D.
europepmc +2 more sources
Detection of inflammation- and neoplasia-associated alterations in human large intestine using plant/invertebrate lectins, galectin-1 and neoglycoproteins [PDF]
Commonly, plant and invertebrate lectins are accepted glycohistochemical tools for the analysis of normal and altered structures of glycans in histology and pathology.
Korabiowska, M. +3 more
core +1 more source
Galectin-3 recruitment to vacuoles containing translocon forming bacteria.
HeLa cells expressing myc-Rac1Q61L and GFP-galectin-3 were infected with WA-314 YopD-ALFA at an MOI of 20 and incubated with NbALFA-580 diluted in cell culture medium. Cells were imaged with a spinning disk microscope recording z-stacks every minute. The
Maren Rudolph (11726318) +4 more
core +1 more source
Biomarkers of lung congestion and injury in acute heart failure
Abstract Acute heart failure (AHF) classification and management are primarily based on lung congestion and/or hypoperfusion. The quantification of the vascular and tissue lung damage is not standard practice though biomarkers of lung injury may play a relevant role in this context.
Marco Guazzi +9 more
wiley +1 more source
How Signaling Molecules Regulate Tumor Microenvironment: Parallels to Wound Repair
It is now suggested that the inhibition of biological programs that are associated with the tumor microenvironment may be critical to the diagnostics, prevention and treatment of cancer.
Peter Gál +8 more
doaj +1 more source
The Role of Galectin-3 in Th17 Differentiation
第十七型輔助型T細胞 (T helper 17 cells, Th17 cells),一個最近被大量研究的輔助型T細胞分支,在病理上被認為是導致自體免疫疾病的主要原因之一。在Th17的細胞分化以及生理作用上,之前研究中已提供許多方面深入的探討。然而在Th17細胞之負向調控機制上,則相對的較缺乏清楚的了解並且仍需要更多的研究。 在此研究中我們發現,與野生控制組相比,Galectin-3基因剔除之輔助型T細胞於體外分化時較容易且大量的分化至Th17細胞,伴隨著主要分泌之細胞激素( IL-17, IL-21 )
朱安翔, Chu, An-Hsiang
core
Cardiac remodelling in the era of the recommended four pillars heart failure medical therapy
Abstract Cardiac remodelling is a key determinant of worse cardiovascular outcome in patients with heart failure (HF) and reduced ejection fraction (HFrEF). It affects both the left ventricle (LV) structure and function as well as the left atrium (LA) and the right ventricle (RV).
Giada Colombo +7 more
wiley +1 more source
Galectin-3 promotes EV71 infection.
(A) Using TALEN, ablation of the galectin-3 gene was performed in RD cells. Two clones of galectin-3 knock-out (G3KO) RD cells were selected. Protein expression of galectin-3 was examined in cell lysates from RD cells and two G3KO clones (G3KO-A1 and ...
Yungling Lee (3454598) +7 more
core +1 more source
Abstract Aims Inflammation plays a critical role in both the development and progression of heart failure (HF), which is a leading cause of morbidity and mortality worldwide. However, the causality between specific inflammation‐related proteins and HF risk remains unclear.
Xian‐Guan Zhu +9 more
wiley +1 more source

