Results 151 to 160 of about 51,657 (292)

Galectin-3 deficiency ameliorates fibrosis and remodeling in dilated cardiomyopathy mice with enhanced mst1 signaling

, 2019
Dilated cardiomyopathy (DCM) is a major cause of heart failure without effective therapy. Fibrogenesis plays a key role in the development of DCM, but little is known of the expression of the profibrotic factor galectin-3 (Gal-3) and its role in DCM ...
Y Su (9103940), WB Zhao (15790577), Mark Ziemann (13101363), DG Donner (10669518), Z Thomas (15790574), JR McMullen (14535023), XJ Du (11181900), A El-Osta (13358853), MN Nguyen (15790571), Q Lu (9040523), J Sadoshima (13427709), H Rafehi (13462170), H Kiriazis (10669515)   +12 more
core  

Eosinophilia Reflects Type 2 Immune Activation in Newly Diagnosed Bullous Pemphigoid, With No Evidence of Charcot‐Leyden Crystals

Allergy, EarlyView.
Janik Fleißner, Tassilo Dege, Sandrine Benoit, Matthias Goebeler, Andreas Kerstan   +4 more
wiley   +1 more source

Shared dysregulation of complement and phosphorylation pathways in the cerebrospinal fluid of encephalitis, Aicardi–Goutières syndrome, and autism

Developmental Medicine &Child Neurology, EarlyView.
Abstract Aim To identify shared and disorder‐specific molecular alterations across encephalitis, Aicardi–Goutières syndrome (AGS), and autism spectrum disorder (ASD) using cerebrospinal fluid (CSF) proteomics. Method In this cross‐sectional case–control study, mass‐spectrometry‐based proteomics was performed on archived CSF samples collected between ...
Omar H. Shadid, Peter G. Hains, Velda X. Han, Jingya Yan, Michael Griffiths, Ignatius Pang, Sushil Bandodkar, Phillip J. Robinson, Russell C. Dale   +8 more
wiley   +1 more source

Cutaneous lymphomas – an update

Histopathology, EarlyView.
Primary cutaneous lymphomas and lymphoproliferative disorders are defined by integrated clinical, histopathological, immunophenotypic and genetic features as diagnostic criteria also in the 5th edition of the WHO classification of haematolymphoid tumors.
Werner Kempf, Christina Mitteldorf
wiley   +1 more source

Male genital lichen sclerosus

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Male genital lichen sclerosus is driven by chronic, occluded exposure of susceptible genital epithelium to urine, rather than infection or autoimmunity. This review synthesizes clinical, anatomical and molecular evidence showing how microincontinence and occlusion initiate inflammation, fibrosis and carcinogenesis, and explains the curative effect of ...
Georgios Kravvas, Rory Barry, Richard E. Watchorn, Christopher B. Bunker   +3 more
wiley   +1 more source

The Oral‐Hepatic Axis: Epidemiological and Mechanistic Links Between Periodontal and Liver Diseases

Journal of Periodontal Research, EarlyView.
This review summarizes current epidemiological, clinical and mechanistic evidence linking periodontitis and chronic liver diseases, highlighting the oral‐gut‐liver axis, shared immunometabolic and nutritional pathways and opportunities for integrated preventive and therapeutic strategies.
Sinem Esra Sahingur, Kinga Grzech‐Leśniak, Samuel F. Suslavich, Janina Golob Deeb   +3 more
wiley   +1 more source

Extracellular Galectin-3/Carbohydrate Interactions Modulate Cancer Cellular Migration. [PDF]

Int J Mol Sci
Fricke MS, Tahir RS, Ural HK, Cloninger MJ.   +3 more
europepmc   +1 more source

Galectin-3 functions an opsonin for efferocytosis in COPD : a process mediated by phosphatidylinositol 3-kinase

, 2011
Galectin-3 functions an opsonin for efferocytosis in COPD : a process mediated by phosphatidylinositol 3 ...
M Holmes (7753346), J Bylund (13718059), S Hodge (13655791), V Mukaro (13605415), P Reynolds (9570635), G Hodge (13287702), H Jersmann (13718062)   +6 more
core  

Understanding exosomes in regenerative dentistry

Periodontology 2000, EarlyView.
Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad, Anton Sculean, Richard J. Miron   +2 more
wiley   +1 more source

Galectin-3 is elevated in Müller glia in human glaucomatous eyes and ocular hypertensive rat eyes and associated with phagocytosing states. [PDF]

Acta Neuropathol Commun
Rombaut A, Wang L, Lardner E, Wong RC, Taul C, Kolko M, Stålhammar G, Brautaset R, Locri F, Williams PA, Tribble JR.   +10 more
europepmc   +1 more source