Results 131 to 140 of about 51,657 (292)
Reduced expression of galectin-1 and galectin-9 by leucocytes in asthma patients
, 2012 Supported in part by EU–Mexico FONCICYT-C002-2009-1 ALA/127249, SAF-2008–02635 and SAF-2011–25834 from the Spanish Ministry of Science and Innovation, INDISNET (Redes Moleculares y Celulares en Enfermedades Inflamatorias) S2011/BMD-2332, MEICA (Molecular
Fuente, Hortensia de la +8 more
core +1 more source
Phytotherapy Research, EarlyView.Overview of the antileukemic effects of Piper nigrum extract in AML. P. nigrum reduced leukemic cell proliferation and glycolytic metabolism through modulation of the PI3K/AKT/mTOR pathway. In vivo, treatment reduced leukemic burden, improved hematological parameters, prolonged survival, and modulated antitumor immune responses.
Natalia Murillo +3 more
wiley +1 more source
Galectin-3 and phagocyte function in asthma
Asthma is a chronic obstructive airway condition that is thought to affect 300 million people globally including around 2.5 million Australians. Asthma-related expenditure in Australia alone is estimated to be over $600 million dollars annually, half of ...
Melanie Erriah (6173654)
core
Galectin-3 protein as a potential therapeutic target in cancer
, 2023 This thesis talks about the role of Galectin-3 as a potential therapeutic target in cancer. Beginning with a detailed examination of its structural intricacies, the thesis provides a solid foundation for understanding the protein's interactions within ...
Obande, Alvin Ngbede
core
Integrative Zoology, EarlyView.High altitudes are challenging for the animals that inhabit these environments. The Xizang plateau frog (Nanorana parkeri) survives in high‐altitude environments through a synergistic strategy of metabolic remodeling and protein expression adjustment to optimize energy efficiency and enhance cellular protection.
Xuejing Zhang +6 more
wiley +1 more source
Gene and protein expression of galectin-3 and galectin-9 in experimental pneumococcal meningitis
, 2007 Inflammation of the subarachnoid and ventricular space contributes to the development of brain damage i.e. cortical necrosis and hippocampal apoptosis in pneumococcal meningitis (PM).
Bellac, Caroline L +9 more
core +1 more source
, 2019 Introduction: The discoveries that sugars are a highly versatile platform to generate biochemical messages and that glycan-specific receptors (lectins) are a link between these signals and their bioactivity explain the interest in endogenous lectins such
Antonio Romero (348813) +1 more
core +1 more source
Serum‐Proteomic Profiling Reveals Distinct Atopic Dermatitis Severity‐Linked Signatures
Allergy, EarlyView.This study aimed to identify a set of serum biomarkers that robustly distinguish prespecified severe from mild atopic dermatitis groups. Serum proteomic profiling distinguishes severe from mild atopic dermatitis, revealing an epithelial enriched severity footprint linked to LDH‐associated tissue injury and Th2/Th22 inflammation.
Jag S. Lally +6 more
wiley +1 more source
, 2011 Background: A growing body of evidence links macrophage activation and fibrosis to the pathogenesis of heart failure (HF). Galectin-3 is one of the most likely mediators between macrophage activation and myocardial fibrosis.
LIN, YEN-HUNG;LIN, LIAN-YU;WU, YEN-WEN;CHIEN, KUO-LIONG;LEE, CHII-MING;HSU, RON-BIN;CHAO, CHIA-LUN;WANG, SHOEI-SHEN;HSEIN, YENH-CHEN;LIAO, LIN-CHU;HO, YI-LWUN;CHEN, MING-FONG +1 more
core +1 more source
Mepolizumab Modifies Blood Eosinophil Proteome and Transcriptome in Severe Eosinophilic Asthma
Allergy, EarlyView.This study investigates the effect of mepolizumab on the proteomic and transcriptomic profile of blood eosinophils in SEA patients. Mepolizumab reduces the migratory capacity and effector‐related molecular signatures of circulating eosinophils in SEA patients.
Pablo Miguéns‐Suárez +14 more
wiley +1 more source