Results 151 to 160 of about 29,735,084 (200)

A proinflammatory stem cell niche drives myelofibrosis through a targetable galectin-1 axis. [PDF]

Sci Transl Med
Li R, Colombo M, Wang G, Rodriguez-Romera A, Benlabiod C, Jooss NJ, O'Sullivan J, Brierley CK, Clark SA, Pérez Sáez JM, Fernández PA, Schoof EM, Porse B, Meng Y, Khan AO, Wen S, Dong P, Zhou W, Sousos N, Murphy L, Clarke M, Olijnik AA, Wong ZC, Karali CS, Sirinukunwattana K, Ryou H, Norfo R, Cheng Q, Carrelha J, Ren Z, Thongjuea S, Rathinam VA, Krishnan A, Royston D, Rabinovich GA, Mead AJ, Psaila B.   +36 more
europepmc   +1 more source

Multi-omics analysis identified LGALS1 (Galectin-1) as a novel therapeutic target for clear cell renal cell carcinoma via targeting epithelial or endothelial cells. [PDF]

Discov Oncol
Tan X, Chen Y, Jiang C, Shao J, Wang X.
europepmc   +1 more source

Galectin-1 Induces the Production of Immune-Suppressive Cytokines in Human and Mouse T Cells. [PDF]

Int J Mol Sci
Herman KD, Holyer I, Humphries DC, Adamska A, Roper JA, Peterson K, Zetterberg FR, Pedersen A, MacKinnon AC, Slack RJ.   +9 more
europepmc   +1 more source

Galectin-1-Induced Tumor Associated Macrophages Repress Antitumor Immunity in Hepatocellular Carcinoma Through Recruitment of Tregs. [PDF]

Adv Sci (Weinh)
Yu X, Qian J, Ding L, Pan C, Liu X, Wu Q, Wang S, Liu J, Shang M, Su R, Guo D, Xie H, Yin S, Zhou L, Zheng S.   +14 more
europepmc   +1 more source

Inhibition of Galectin-1 and Androgen Receptor Axis Enhances Enzalutamide Treatment in Enzalutamide Resistant Prostate Cancer. [PDF]

Cancers (Basel)
Wang HC, Gao AC, Xia R, Wu CT, Hsu SW, Chen CH, Shih TC.   +6 more
europepmc   +1 more source

Mesenchymal stromal cells attenuate primary sjogren's syndrome by modulating PD-1⁺CXCR5^- T peripheral helper cells via galectin-1. [PDF]

Stem Cell Res Ther
Zhang S, Yin F, Chai R, Li T, Gao Y, Chen X, Yao G, Tang X, Han X, Tsao BP, Geng L, Sun L.   +11 more
europepmc   +1 more source

The expression profiles of the galectin gene family in primary and metastatic papillary thyroid carcinoma with particular emphasis on galectin-1 and galectin-3 expression [PDF]

Experimental and Molecular Pathology, 2014
Introduction Galectin family members have been demonstrated to be abnormally expressed in cancer at the protein and mRNA level. This study investigated the levels of galectin proteins and mRNA expression in a large cohort of patients with papillary ...
Vinod Gopalan, Alfred Lam, Armin Ariana   +2 more
exaly   +2 more sources

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Therapeutic Potential of Galectin-1 and Galectin-3 in Autoimmune Diseases

Current Pharmaceutical Design, 2022
:Galectins are a highly conserved protein family that binds to β-galactosides. Different members of this family play a variety of biological functions in physiological and pathological processes such as angiogenesis, regulation of immune cell activity, and cell adhesion.
Yi-Sheng, He, Yu-Qian, Hu, Kun, Xiang, Yue, Chen, Ya-Ting, Feng, Kang-Jia, Yin, Ji-Xiang, Huang, Jie, Wang, Zheng-Dong, Wu, Gui-Hong, Wang, Hai-Feng, Pan   +10 more
openaire   +2 more sources

Taloside Inhibitors of Galectin‐1 and Galectin‐3

Chemical Biology & Drug Design, 2012
Galectin‐1 and galectin‐3 have roles in cancer and inflammation. Galectin‐1 has recently emerged as a significant protein produced by tumour cells to promote tumour development, angiogenesis and metastasis and consequently represents an important target to inhibit.
Collins, Patrick M, Oberg, Christopher T, Leffler, Hakon, Nilsson, Ulf J, Blanchard, Helen   +4 more
openaire   +3 more sources