Results 171 to 180 of about 18,892,704 (362)

Association between sleep patterns and galectin-3 in a Chinese community population

BMC Public Health
Background Irregular sleep patterns have been associated with inflammation. Galectin-3, a novel biomarker, plays an important role in inflammation. We investigated the relationship between sleep patterns and galectin-3 in a Chinese population.
Lin Liu, Juanying Zhen, Shuyun Liu, Lijie Ren, Guoru Zhao, Jianguo Liang, Aimin Xu, Chao Li, Jun Wu, Bernard Man Yung Cheung   +9 more
doaj   +1 more source

Tingkat Ekspresi Galectin-3 sebagai Penanda Lesi Jinak dan Lesi Ganas pada Tiroid [PDF]

, 2015
Karsinoma tiroid merupakan keganasan tersering organ endokrin sebagian besar berasal dari sel folikular. Kasus terbanyak adalah karsinoma tiroid papiler dan terbanyak kedua adalah karsinoma tiroid folikular.
Aspitriani, A. (Aspitriani), Ellys, E. (Ellys), Kartika, I. (Ika), Yuwono, Y. (Yuwono)   +3 more
core  

Spatial multi‐omics identifies a NOTCH3‐mediated capillary–mCAF crosstalk driving immune exclusion in hepatocellular carcinoma

iMeta, EarlyView.
Spatial multi‐omics defines a DLL4–NOTCH3–driven capillary–mCAF axis orchestrating fibrotic remodeling and immune exclusion in hepatocellular carcinoma tumor cores, conferring immune checkpoint blockade resistance. Targeting stromal NOTCH3 disrupts this pro‐fibrotic niche, enhances T cell infiltration, and synergizes with anti‐PD‐1 therapy ...
Fansen Ji, Haochen Li, Qi Wang, Xiaojuan Wang, Jiawei Zhang, Ying Xiao, Huan Li, Hao Liu, Tanqing Long, Boyang Wu, Hao Chen, Haoming Xia, Xinquan Liu, Chuanrui Xu, Yibo Gao, Bingjun Tang, Juan Liu, Shizhong Yang, Jiahong Dong   +18 more
wiley   +1 more source

Activated Tim-3/Galectin-9 participated in the development of multiple myeloma by negatively regulating CD4 T cells

Hematology
The interaction between Tim-3 on T cells and its ligand Galectin-9 negatively regulates the cellular immune response. However, the regulation of Tim-3/Galectin-9 on CD4 T cell subsets in multiple myeloma (MM) remains unclear. The aim of this study was to
Rui Zhang, Shuang Chen, Tingting Luo, Sha Guo, Jianhua Qu   +4 more
doaj   +1 more source

Sensing ligand binding to a clinically relevant lectin by tryptophan fluorescence anisotropy [PDF]

, 2011
Increasing insights into the involvement of endogenous lectins in disease processes fuel the interest to develop potent inhibitors. As a consequence, robust assay procedures are required. Due to their activity as adhesion/growth-regulatory effectors this
André, Sabine, Büchner, Claudia, Doose, Sören, Gabius, Hans-Joachim, Göhler, Antonia, Kaltner, Herbert   +5 more
core   +1 more source

Exploring the role of galectin 3 in kidney function: a genetic approach [PDF]

, 2005
Maurice Bichara, Amel Attmane-Elakeb, Dennis Brown, Marie Essig, Zoubida Karim, Martine Muffat‐Joly, Laetitia Micheli, Isabelle Eude-Le Parco, Françoise Cluzeaud, Michel Peuchmaur, J. P. Bonvalet, Françoise Poirier, Nicolette Farman   +12 more
openalex   +1 more source

Galectin-3 Activation and Inhibition in Heart Failure and Cardiovascular Disease: An Update

Theranostics, 2018
Galectin-3 is a versatile protein orchestrating several physiological and pathophysiological processes in the human body. In the last decade, considerable interest in galectin-3 has emerged because of its potential role as a biotarget.
N. Suthahar, W. Meijers, Herman H. W. Silljé, J. Ho, Fu-Tong Liu, R. de Boer   +5 more
semanticscholar   +1 more source

Beyond Traditional Screening: The Future of Heart Failure Detection With Biomarkers and AI

iNew Medicine, EarlyView.
Advancing HF Screening: Integrating Technology and Risk Factors Across Eras. This diagram provides a comprehensive review of the historical developments and projected trends of heart failure (HF) screening methodologies, with the prevalent risk factors for HF depicted at the base.
Xiaofeng Fang, Yinbo Xu, Yiting Zhao, Liuyi Li, Zhengyi Cheng, Zhongqi Zhang, Yuhang Luo, Qiaoling Liu, Chen Gong, Shichun Shen   +9 more
wiley   +1 more source

Response to Letter to the Editor Entitled “Short and Long-Term Prognostic Significance of Galectin-3 in Patients with ST-Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention” [PDF]

, 2023
Uğur Köktürk, Hamdi Püşüroğlu, Mustafa Umut Somuncu, Begüm Uygur, Nilgün Işıksaçan, Aydın Yildirim   +5 more
openalex   +1 more source

Quantifying Protein–Glycan Interactions Using Native Mass Spectrometry

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Interactions between glycan‐binding proteins (GBPs) and carbohydrates (glycans) are essential to many biological processes relevant to human health and disease. For most GBPs, however, their glycan interactome—the repertoire of glycans recognized and their specificities—is poorly defined.
Duong T. Bui, Elena N. Kitova, Ling Han, Lara K. Mahal, John S. Klassen   +4 more
wiley   +1 more source