Results 1 to 10 of about 29,735,084 (200)

Galectin Family Members: Emerging Novel Targets for Lymphoma Therapy?

Frontiers in Oncology, 2022
The galectin family of proteins has high affinity with β-galactoside-containing glycans. These proteins participate in cell growth and differentiation, cell adhesion, cell signal transduction, cell apoptosis, and other cellular activities.
Yuanwei Shi, Yuanwei Shi, Danting Tang, Danting Tang, Xiaoqi Li, Xiaoqi Li, Xiaoli Xie, Yufu Ye, Yufu Ye, Lijuan Wang, Lijuan Wang   +10 more
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Prognostic Significance of Galectin-1 but Not Galectin-3 in Patients With Lung Adenocarcinoma After Radiation Therapy

Frontiers in Oncology, 2022
IntroductionTo investigate the role of tumor galectin-1 and galectin-3 in patients with lung adenocarcinoma after definitive radiation therapy.MethodsA total of 41 patients with localized lung adenocarcinoma undergoing thoracic radiation therapy without ...
Chun-Chieh Huang, Chun-Chieh Huang, I-Chieh Chuang, Yu-Li Su, Hao-Lun Luo, Ya-Chun Chang, Ya-Chun Chang, Jo-Ying Chen, Chang-Chun Hsiao, Chang-Chun Hsiao, Eng-Yen Huang, Eng-Yen Huang   +11 more
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Evaluation of galectins 1 and 3 expression in canine melanoma [PDF]

Pesquisa Veterinária Brasileira, 2021
: Canine melanoma is a frequently-occuring neoplasm in dogs and presents as malignant and highly metastatic in this context, studies that contribute to the understanding of the tumor microenvironment in melanoma include the role of galectins.
Jéssica S. Garcia, Nicolle G.T.Q. Hazarbassanov, Júlia C. Nakamura, Victor Nowosh, Bruno Cogliati, Lilian Rose Marques de Sá, Cristina O. Massoco   +6 more
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Galectin-1 induces a tumor-associated macrophage phenotype and upregulates indoleamine 2,3-dioxygenase-1

iScience, 2023
Summary: Galectins are a group of carbohydrate-binding proteins with a presumed immunomodulatory role and an elusive function on antigen-presenting cells.
Asha M. Rudjord-Levann, Zilu Ye, Lise Hafkenscheid, Sabrina Horn, Renske Wiegertjes, Mathias A.I. Nielsen, Ming Song, Caroline B.K. Mathiesen, Jesse Stoop, Sean Stowell, Per Thor Straten, Hakon Leffler, Sergey Y. Vakhrushev, Sally Dabelsteen, Jesper V. Olsen, Hans H. Wandall   +15 more
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Galectin-1 in Obesity and Type 2 Diabetes

Metabolites, 2022
Galectin-1 is a carbohydrate-binding protein expressed in many tissues. In recent years, increasing evidence has emerged for the role of galectin-1 in obesity, insulin resistance and type 2 diabetes. Galectin-1 has been highly conserved through evolution
Emanuel Fryk, Vagner R. R. Silva, Per-Anders Jansson   +2 more
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Galectin-1 accelerates high-fat diet-induced obesity by activation of peroxisome proliferator-activated receptor gamma (PPARγ) in mice

Cell Death and Disease, 2021
Galectin-1 contains a carbohydrate-recognition domain (CRD) as a member of the lectin family. Here, we investigated whether galectin-1 regulates adipogenesis and lipid accumulation.
Jung-Hwan Baek, Da-Hyun Kim, Jaegyeong Lee, Seok-Jun Kim, Kyung-Hee Chun   +4 more
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Galectin-1, -3 and -9 Expression and Clinical Significance in Squamous Cervical Cancer. [PDF]

PLoS ONE, 2015
Galectins are proteins that bind β-galactoside sugars and provide a new type of potential biomarkers and therapeutic targets in cancer. Galectin-1, -3 and -9 have become the focus of different research groups, but their expression and function in ...
Simone Punt, Victor L Thijssen, Johannes Vrolijk, Cornelis D de Kroon, Arko Gorter, Ekaterina S Jordanova   +5 more
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Differential Cellular Expression of Galectin-1 and Galectin-3 After Intracerebral Hemorrhage

Frontiers in Cellular Neuroscience, 2019
Intracerebral hemorrhage (ICH) is a devastating sub-type of stroke with no proven treatment. Given the emerging role of Galectin-1 and Galectin-3 in neuroimmune responses, the objective of the current manuscript is to elucidate hemorrhagic-injury induced
Frederick Bonsack, Sangeetha Sukumari-Ramesh   +1 more
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Galectin 1 and Superoxide Dismutase are Involved in Wound Healing by Larval Therapy [PDF]

Journal of Genetic Resources, 2019
Galectin-1 and superoxide dismutase are two known molecules in the wound healing process that induce such healing by different mechanisms in the wound site. Larval therapy is one of the methods use by Lucilia sericata fly larvae, nowadays returned to the
Shadi Riki, Mohammad Ali Sabokkhiz, Toktam Hajar, Madjid Momeni-Moghaddam   +3 more
doaj   +1 more source

Maternal Galectins and Glucose Regulation in Pregnancy: Chronic vs. Acute Metabolic Adaptations [PDF]

Diabetes & Metabolism Journal
Background Galectins (gal) are glycan-binding proteins that regulate maternal adaptations during pregnancy, but their role in pregnancy-associated metabolic homeostasis is unclear.
Mariana G. Garcia, Ebba Hamann, Evelyn A. Huhn, Karen Forbes, Pia Roser, Marie-Therese Weiser-Fuchs, Anna M. Dieberger, Bence Csapo, Barbara Obermayer-Pietsch, Mireille N.M. van Poppel, Herbert Fluhr, Evelyn Jantscher-Krenn, Sandra M. Blois   +12 more
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