Results 11 to 20 of about 29,735,084 (200)

Galectin-1 and Galectin-3 in Chronic Pancreatitis [PDF]

Laboratory Investigation, 2000
Galectin-1 and galectin-3 have important functions in cell-cell interactions, cell adhesion to extracellular matrix, the organization of extracellular matrix, and tissue remodeling. To assess their potential role in chronic pancreatitis (CP), we examined their expression by Northern blot analysis, in situ hybridization, immunohistochemistry, and ...
Wang L, Friess H, Zhu Z, Frigeri L, Zimmermann A, Korc M, Berberat PO, Büchler MW   +7 more
openaire   +4 more sources

Reduced expression of galectin-1 and galectin-9 by leucocytes in asthma patients

Clinical and Experimental Immunology, 2012
Summary Accumulating evidence shows that galectins play roles in the initiation and resolution phases of inflammatory responses by promoting anti- or proinflammatory effects. This study investigated the presence of three members of the galectin family (galectin-1, -3 and -9) in induced sputum samples of asthma patients, as well as their ...
S, Sanchez-Cuellar, H, de la Fuente, A, Cruz-Adalia, A, Lamana, D, Cibrian, R M, Giron, A, Vara, F, Sanchez-Madrid, J, Ancochea   +8 more
openaire   +4 more sources

Galectin-1 and galectin-3 in male reproduction - impact in health and disease. [PDF]

Semin Immunopathol
Abstract The formation and differentiation of mature, motile male germ cells, which can fertilize the egg and ensure successful implantation and development of a healthy embryo, are essential functions of the testis and epididymis. Spermatogenesis is a complex, multistep process that results in the formation of motile haploid gametes,
Fijak M, Hasan H, Meinhardt A.
europepmc   +3 more sources

From adipokine to integrator: longitudinal galectin-1 changes mirror glycemic, hepatic, renal, and lipid remodeling after bariatric surgery [PDF]

Nutrition & Diabetes
Background Circulating galectin-1 levels increase with adiposity, and experimental data implicate this adipokine in the development of metabolic dysfunction.
Te-Hung Chen, Young-Jen Lin, Wei-Shiung Yang, Po-Chu Lee, Chiung-Nien Chen, Ming-Tsan Lin, Po-Jen Yang   +6 more
doaj   +2 more sources

Oxidized galectin-1 reduces lipopolysaccharide-induced increase of proinflammatory cytokine mRNA in cultured macrophages

Clinical, Cosmetic and Investigational Dentistry, 2011
Yukie Kogawa1, Kou Nakajima1, Kenichi Sasaguri1, Nobushiro Hamada2, Haruhisa Kawasaki3, Sadao Sato1, Toshihiko Kadoya4, Hidenori Horie51Department of Orthodontics, 2Department of Oral Microbiology, Kanagawa Dental College, Yokosuka; 3Keio University ...
Yukie Kogawa, Kou Nakajima, Kenichi Sasaguri, et al   +3 more
doaj   +1 more source

The relationship between galectin-1 expression and the efficacy of anti-PD-1 therapy for non-small cell lung cancer patients [PDF]

Scientific Reports
We herein examined the potential of galectin-1 expression to predict the efficacy of anti-PD-1 therapy for patients with non-small cell lung cancer (NSCLC).
Mari Tone, Yukihiro Yano, Junji Uchida, Masahide Mori, Hisashi Wada, Yoshito Takeda, Atsushi Kumanogoh, Kota Iwahori   +7 more
doaj   +2 more sources

The role of galectin-3 and galectin-9 in the chronic inflammation of rheumatoid arthritis [PDF]

, 2009
Fibroblasts are important regulators of inflammatory processes. The phenotype of fibroblasts differ according to anatomical site which may dtermine immune functions such as leukocyte accumulation and predilection for inflammatory disease in certain ...
Bik, Magadelena Anna
core   +7 more sources

Galectin-1 for Neuroprotection? [PDF]

Immunity, 2012
Classically activated microglia (M1) are believed to play a key role in neuronal degeneration in multiple sclerosis (MS). In this issue of Immunity, Starossom et al. (2012) show that Galectin-1 exerts a neuroprotective function through glycosylation-dependent inactivation with M1 cells.
Nonaka, Motohiro, Fukuda, Minoru
openaire   +2 more sources

Galectins in the Tumor Microenvironment: Focus on Galectin-1 [PDF]

, 2020
In the last decades, the focus of cancer research has moved from epithelial cells to the tumor milieu, in an effort to better understand tumor development and progression, and with the important end goal of translating this knowledge into effective therapies.
Neus, Martínez-Bosch, Pilar, Navarro
openaire   +2 more sources

Overexpression of Galectin-1 and Galectin-3 in hepatocellular carcinoma

Liver Research, 2020
Galectins (Gals) are evolutionarily conserved proteins that bind to β-galactoside containing glycans. Abnormal expression of Gals is associated with the development, progression, and metastasis of different types of cancer. Among the 11 Gals identified in humans, the roles of Gal-1 and Gal-3 have been extensively investigated in various tumors.
Setayesh, Tahereh, Colquhoun, Steven D, Wan, Yu-Jui Yvonne   +2 more
openaire   +5 more sources