Results 41 to 50 of about 29,735,084 (200)

Survival mechanisms in B lymphoid malignancies and associated therapies [PDF]

, 2011
PhDThe apoptotic pathway plays critical roles in regulating lymphocyte survival throughout B cell development, maturation and differentiation. The whole process involves clonal expansion. In the normal B lymphocyte population the majority of cells and
Su, Bo
core   +4 more sources

Galectin-1 in myelin repair

Oncotarget, 2016
Fil: Pasquini, Laura Andrea. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Físico-Química Biológicas "Prof. Alejandro C. Paladini". Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica.
Rinaldi, Mariana, Thomas, Laura, Pasquini, Laura Andrea   +2 more
openaire   +3 more sources

Galectin-1 Restores Immune Tolerance to Liver Transplantation Through Activation of Hepatic Stellate Cells

Cellular Physiology and Biochemistry, 2018
Background/Aims: Immune tolerance is considered the only way to manage liver transplantation (LT). The current study hypothesized that galectin-1 via the activation of hepatic stellate cells (HSCs) is capable of inducing immune tolerance in LT.
Zhi-Jun Jiang, Qing-Hua Shen, Hai-Yong Chen, Zhe Yang, Ming-Qi Shuai, Shusen Zheng   +5 more
doaj   +1 more source

Galectin-1 and galectin-3 as modulators of systemic CD4+ T-lymphocyte balance in colorectal cancer

Бюллетень сибирской медицины
Aim. To evaluate the relationships between plasma levels of galectin-1 and galectin-3 and the composition of CD4+ T-lymphocyte subpopulations (Th1, Th17, and Treg) in patients with colorectal cancer (CRC) and to determine a direct in vitro modulatory ...
V. S. Poletika, G. V. Reingardt, A. V. Kurnosenko, Yu. V. Kolobovnikova, O. I. Urazova   +4 more
doaj   +1 more source

Expression of Galectin-1 and Galectin-3 in Human Fetal Thyroid Gland [PDF]

Journal of Histochemistry & Cytochemistry, 2003
High levels of expression of galectin-1 and galectin-3, the β-galactoside-binding proteins, have been recently described in malignant thyroid tumors but not in adenomas nor in normal thyroid tissue. However, there are no data about the expression of these galectins during fetal thyroid development.
Svetlana B, Savin, Dubravka S, Cvejić, Miroslava M, Janković   +2 more
openaire   +2 more sources

New Treatment Strategy Targeting Galectin-1 against Thyroid Cancer

Cells, 2021
Although the overall survival rate of papillary or follicular thyroid cancers is good, anaplastic carcinomas and radio iodine refractory cancers remain a significant therapeutic challenge.
Laetitia Gheysen, Laura Soumoy, Anne Trelcat, Laurine Verset, Fabrice Journe, Sven Saussez   +5 more
doaj   +1 more source

Galectin-1 promotes gastric cancer peritoneal metastasis through peritoneal fibrosis

BMC Cancer, 2023
Background Peritoneal metastasis is one of the main causes of death in patients with gastric cancer (GC). Galectin-1 regulates various undesirable biological behaviors in GC and may be key in GC peritoneal metastasis. Methods In this study, we elucidated
Xianhe Shen, Huilan Liu, Haihua Zhou, Zhiyi Cheng, Guiyuan Liu, Chuanjiang Huang, Rongrong Dou, Fuxing Liu, Xiaolan You   +8 more
doaj   +1 more source

The role of galectin-1 and galectin-3 in the mechanisms of T-cell immune response dysregulation in colon cancer

Бюллетень сибирской медицины, 2020
The aim of the study was to characterize the features of the subpopulation composition and cytokine-secretory activity of T lymphocytes (Th1, Th17 and Treg) in relation to the concentration of galectin-1 and galectin-3 in the blood of patients with colon
V. S. Poletika, Yu. V. Kolobovnikova, O. I. Urazova, O. A. Vasileva, A. I. Dmitrieva, K. I. Yankovich, V. V. Novitsky, L. M. Ryabova, M. Yu. Grishchenko   +8 more
doaj   +1 more source

Galectin-1 and Galectin-3 mRNA expression in renal cell carcinoma [PDF]

BMC Clinical Pathology, 2014
AbstractBackgroundGalectins are known to regulate cell differentiation and growth as well as cell adhesion and apoptosis. Galectins have been discussed as possible prognosticators for survival in renal cell cancer (RCC) and other urological tumors. They might also play an emerging role as possible new marker-proteins for RCC. In this study, we analyzed
von Klot, Christoph-A, Kramer, Mario W, Peters, Inga, Hennenlotter, Joerg, Abbas, Mahmoud, Scherer, Ralph, Herrmann, Thomas RW, Stenzl, Arnulf, Kuczyk, Markus A, Serth, Juergen, Merseburger, Axel S   +10 more
openaire   +2 more sources

Galectin-1 as a predictive biomarker in ovarian cancer

Journal of Ovarian Research, 2021
Aim There is an urgent need to set up a useful biomarker for ovarian cancer. Galectin-1 is a promising carbohydrate-binding protein which plays a remarkable role in various malignancies yet its clinical significance is questionable.
Mahak Masoodi, Zafar A. Shah, Afaq H. Beigh, Sheikh Zahoor Ahmad, Abdul Wahid Mir, Besina Yasin, Roohi Rasool, Khalid Z. Masoodi, Gull Mohammad Bhat   +8 more
doaj   +1 more source