Results 61 to 70 of about 29,735,084 (200)

Galectin-1 reduces the severity of dextran sulfate sodium (DSS)-induced ulcerative colitis by suppressing inflammatory and oxidative stress response

open access: yesBiomolecules & Biomedicine, 2020
Ulcerative colitis is an inflammatory bowel disease that affects a large number of people around the world. Galectin-1 is a β-galactoside-binding lectin with a broad range of biological activities.
Pelin Arda-Pirincci, Guliz Aykol-Celik
doaj   +1 more source

Galectin-1 and galectin-3 expression in equine mesenchymal stromal cells (MSCs), synovial fibroblasts and chondrocytes, and the effect of inflammation on MSC motility

open access: yesStem Cell Research & Therapy, 2017
Background Mesenchymal stromal cells (MSCs) can be used intra-articularly to quell inflammation and promote cartilage healing; however, mechanisms by which MSCs mitigate joint disease remain poorly understood. Galectins, a family of β-galactoside binding
Heidi L. Reesink   +7 more
doaj   +1 more source

Placental Expression Patterns of Galectin-1, Galectin-2, Galectin-3 and Galectin-13 in Cases of Intrauterine Growth Restriction (IUGR) [PDF]

open access: yesInternational Journal of Molecular Sciences, 2016
Galectins (gal) are members of the mammalian β-galactoside-binding proteins and recognize Galβ1-4GlcNAc and Galβ1-4GalNac (Thomsen-Friedenreich antigen (TF)) sequences of several cell surface oligosaccharides. In this study, gal-1, -2, -3 and -13 were investigated systematically in the trophoblast and decidua compartment of intrauterine growth ...
Stefan Hutter   +7 more
openaire   +3 more sources

Galectin-1 and galectin-3 expression in human bladder transitional-cell carcinomas [PDF]

open access: yesInternational Journal of Cancer, 1999
Galectin-1 and galectin-3 are galactoside-binding proteins involved in different steps of tumor progression and potential targets for therapy. We have investigated the expression of these galectins in 38 human bladder transitional-cell carcinomas of different histological grade and clinical stage and in 5 normal urothelium samples.
CINDOLO, LUCA   +9 more
openaire   +5 more sources

Serum levels of galectin-1, galectin-3, and galectin-9 are associated with large artery atherosclerotic stroke [PDF]

open access: yesScientific Reports, 2017
AbstractThe aim of this study was to assess the expression patterns of serum galectin-1 (Gal-1), galectin-3 (Gal-3), galectin-9 (Gal-9), and galectin-3 binding protein (Gal-3BP) and their associations with stroke outcome in large artery atherosclerotic (LAA) stroke.
Xin-Wei He   +6 more
openaire   +2 more sources

Galectin-1-Induced Autophagy Facilitates Cisplatin Resistance of Hepatocellular Carcinoma. [PDF]

open access: yesPLoS ONE, 2016
Hepatocellular carcinoma (HCC) is one of the most common cancers in Taiwan. Although chemotherapy is the primary treatment for HCC patients, drug resistance often leads to clinical failure.
Yu-Chi Su   +7 more
doaj   +1 more source

Production and characterization of a monoclonal antibody able to discriminate galectin-1 from galectin-2 and galectin-3 [PDF]

open access: yesGlycobiology, 1998
Antisera raised against galectin-1 exhibit crossreactivities with other galectins or related molecules. In order to overcome this problem, a monoclonal antibody to human brain galectin-1 was obtained by selecting clones without reactivity toward galectin-3.
J D, Cornillot   +7 more
openaire   +2 more sources

Increased Adiposity, Dysregulated Glucose Metabolism and Systemic Inflammation in Galectin-3 KO Mice [PDF]

open access: yes, 2013
PMCID: PMC3579848This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
Karla J. Castellanos (7918193)   +35 more
core   +1 more source

Galectins 1, 3 and 9 in patients with systemic lupus erythematosus: is there an association with disease activity or clinical manifestations?

open access: yesСовременная ревматология
Objective. To compare serum concentrations of galectins 1, 3 and 9 in women with systemic lupus erythematosus (SLE) and healthy donors; to assess the relationship of these biomarkers with disease activity and specific clinical manifestations.Material and
L. V. Kondrateva   +5 more
doaj   +1 more source

Additional file 2: of Nuclear FAM289-Galectin-1 interaction controls FAM289-mediated tumor promotion in malignant glioma

open access: yes, 2019
Figure S2. Knockdown or overexpression of Galectin-1 in U251 or U87-MG cells. A. Galectin-1 was knocked down in U251 cell lines by SiRNA1–3. Galectin-1 siRNA2 and siRNA3 significantly reduced Galectin-1expression. B.
Shi Ma (217876)   +12 more
core   +1 more source

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