Results 71 to 80 of about 29,735,084 (200)

Galectin-1 Pulls the Strings on VEGFR2 [PDF]

Cell, 2014
Anti-vascular endothelial growth factor (VEGF) cancer immunotherapy targets angiogenesis but development of resistance in patients is common. In this issue of Cell, Croci et al. identify a complex set of mechanisms by which galectin-1 prolongs cell-surface retention of VEGF receptor 2 (VEGFR2) and stimulates VEGF-independent tumor angiogenesis.
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Quantitative Expression of C-Type Lectin Receptors in Humans and Mice [PDF]

, 2012
C-type lectin receptors, their adaptor molecules and S-type lectins (galectins) are involved in the recognition of glycosylated self-antigens and pathogens.
Lech, Maciej, Günthner, Roman, Regina Gröbmayr, Römmele, Christoph, Heni Eka Susanti, Susanti, Heni Eka, Heni Susanti, Maciej Lech, Roman Günthner, Hans-Joachim Anders, Christoph Römmele, Gröbmayr, Regina, Anders, Hans-Joachim   +12 more
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Expressão dos genes que codificam as proteínas anexina-1 e galectina-1 nos pólipos rinossinusais e sua modulação pelo glicocorticoide Expression of genes that encode the annexin-1 and galectin-1 proteins in nasal polyposis and their modulation by glucocorticoid

Brazilian Journal of Otorhinolaryngology, 2010
A fisiopatologia da polipose rinossinusal não é totalmente compreendida, apesar de várias hipóteses em relação ao seu processo inflamatório. OBJETIVOS: Estudo prospectivo da expressão dos genes das proteínas, anexina-1 e a galectina-1, que têm ação anti ...
Atílio Maximino Fernandes, Erica Babeto, Paula Rahal, Paola Jocelan Scarin Provazzi, Claudia Augusta Hidalgo, Wilma T Anselmo-Lima   +5 more
doaj   +1 more source

Optimization of the inter-domain structure of galectin-9 for recombinant production [PDF]

, 2013
香川大学Kagawa University博士（医学）Abstract We previously developed a stable form of galectin-9, an immunomodulatory animal lectin with a truncated linker peptide (G9Null), to overcome the protease sensitivity of wild-type galectin-9.
Itoh, Aiko, イトウ, アイコ, 伊藤, 愛子   +2 more
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Galectin expression profiling identifies galectin-1 and Galectin-9Δ5 as prognostic factors in stage I/II non-small cell lung cancer.

PLoS ONE, 2014
Approximately 30-40% of the patients with early stage non-small cell lung cancer (NSCLC) will present with recurrent disease within two years of resection.
Iris A Schulkens, Roy Heusschen, Vivian van den Boogaart, Robert-Jan van Suylen, Anne-Marie C Dingemans, Arjan W Griffioen, Victor L Thijssen   +6 more
doaj   +1 more source

“Supra”molecular Recognition of Galectin 1

Chemistry & Biology, 2007
In this issue of Chemistry & Biology, Belitsky et al. [1] elegantly describe the use of supramolecular complexes of sugars to multivalently target Galectin-1 (Gal-1), a lectin involved in the organization of cell surface glycoproteins, signaling, cell death, and cancer metastasis.
Disney, Matthew D., Childs-Disney, Jessica L.   +1 more
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Galectin-1 as a potential cancer target [PDF]

British Journal of Cancer, 2005
Galectins are a family of structurally related carbohydrate-binding proteins, which are defined by their affinity for poly-N-acetyllactosamine-enriched glycoconjugates and sequence similarities in the carbohydrate recognition domain. Galectin-1, a member of this family, contributes to different events associated with cancer biology, including tumour ...
openaire   +3 more sources

Additional file 4: of Nuclear FAM289-Galectin-1 interaction controls FAM289-mediated tumor promotion in malignant glioma

, 2019
Figure S4. The effect of FAM289 and Galectin-1 on each other’s expression. A. Overexpression FAM289 or Galectin-1 did not affect each other’s expression. B. Knock down FAM289 or Galectin-1 did not affect each other’s expression.
Shi Ma (217876), Yan Ding (39795), Qiu Zhang (239441), Long Dai (7356110), Xing Guo (103312), Yu Huang (15093), Mu Wu (7356107), Hao Peng (231482), Dong Li (212687), Xu Ruan (7356116), Meng Shan (7356113), Jun Tang (32983), Jue Wang (58890)   +12 more
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Serum Galectin‐1, Galectin‐9, and YKL‐40 levels in bipolar disorder and their relationship with cognitive functions

Brain and Behavior
Purpose The number of studies conducted on the role of neuroinflammation in the etiopathogenesis of bipolar disorder has been increasing in recent years.
Elcicek Selahaddin, Demir Bahadir, Sahin Sengul, Taysi Seyithan, Ulusal Hasan, Elboga Gülcin, Altindag Abdurrahman   +6 more
doaj   +1 more source

Galectins: a potential pharmacological target

Бюллетень сибирской медицины
Aim. To consider the use of galectin-1 and galectin-3 inhibitors as potential pharmacological targets in antitumor and antifibrotic therapy.The lecture includes the analysis of experimental research and review articles presented in the PubMed database. A
V. A. Serebryakova, O. E. Vaizova, E. L. Golovina, V. V. Kochubey   +3 more
doaj   +1 more source